Mitogen-Activated Protein Kinase Phosphatases
                             
                            
                            
                                
                                    
                                            
	"Mitogen-Activated Protein Kinase Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				A subcategory of phosphohydrolases that are specific for MITOGEN-ACTIVATED PROTEIN KINASES. They play a role in the inactivation of the MAP KINASE SIGNALING SYSTEM.
    
			
			
				
				
					
						| Descriptor ID | D054639 | 
					
						| MeSH Number(s) | D08.811.277.352.650.587 D12.644.360.445 D12.776.476.445 | 
					
						| Concept/Terms |  | 
					
				
			 
			
				Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinase Phosphatases".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinase Phosphatases".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Mitogen-Activated Protein Kinase Phosphatases" by people in this website by year, and whether "Mitogen-Activated Protein Kinase Phosphatases" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2005 | 0 | 1 | 1 | 
| 2009 | 1 | 0 | 1 | 
| 2010 | 1 | 1 | 2 | 
| 2013 | 0 | 1 | 1 | 
| 2014 | 0 | 1 | 1 | 
| 2015 | 1 | 0 | 1 | 
| 2016 | 1 | 0 | 1 | 
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				Below are the most recent publications written about "Mitogen-Activated Protein Kinase Phosphatases" by people in Profiles.
						
					
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								DUSP22 rearrangement is associated with a distinctive immunophenotype but not outcome in patients with systemic ALK-negative anaplastic large cell lymphoma. Haematologica. 2023 06 01; 108(6):1604-1615. 
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								Lymphomatoid papulosis with DUSP22-IRF4 rearrangement: A case report and literature review. J Cutan Pathol. 2023 Aug; 50(8):711-716. 
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								Fragment-based design, synthesis, biological evaluation, and SAR of 1H-benzo[d]imidazol-2-yl)-1H-indazol derivatives as potent PDK1 inhibitors. Bioorg Med Chem Lett. 2017 12 15; 27(24):5473-5480. 
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								Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis. Oncotarget. 2016 Sep 06; 7(36):57593-57605. 
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								Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion. Breast Cancer Res Treat. 2016 08; 158(3):441-54. 
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								TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity. Cell Signal. 2016 Jan; 28(1):145-51. 
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								NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis. Cell Death Dis. 2015 Aug 06; 6:e1841. 
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								NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1a-stimulated angiogenesis. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2023-32. 
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								Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. Carcinogenesis. 2013 Apr; 34(4):885-92. 
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								Profiling of residual breast cancers after neoadjuvant chemotherapy  identifies DUSP4 deficiency as a mechanism of drug resistance. Nat Med. 2012 Jul; 18(7):1052-9.