Receptors, Thyroid Hormone
"Receptors, Thyroid Hormone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specific high affinity binding proteins for THYROID HORMONES in target cells. They are usually found in the nucleus and regulate DNA transcription. These receptors are activated by hormones that leads to transcription, cell differentiation, and growth suppression. Thyroid hormone receptors are encoded by two genes (GENES, ERBA): erbA-alpha and erbA-beta for alpha and beta thyroid hormone receptors, respectively.
| Descriptor ID |
D011988
|
| MeSH Number(s) |
D12.776.624.664.700.830 D12.776.826.850
|
| Concept/Terms |
Receptors, Thyroxine- Receptors, Thyroxine
- T4 Receptors
- Receptors, T4
- T4 Receptor
- Thyroxine Receptor
- Thyroxine Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Thyroid Hormone".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Thyroid Hormone".
This graph shows the total number of publications written about "Receptors, Thyroid Hormone" by people in this website by year, and whether "Receptors, Thyroid Hormone" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 3 | 0 | 3 |
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 1 | 4 |
| 1999 | 0 | 3 | 3 |
| 2000 | 1 | 1 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 4 | 1 | 5 |
| 2004 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 3 | 1 | 4 |
| 2008 | 1 | 3 | 4 |
| 2009 | 2 | 1 | 3 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 3 | 5 |
| 2018 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Thyroid Hormone" by people in Profiles.
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No Dataset Left Behind: Mechanistic Insights into Thyroid Receptor Signaling Through Transcriptomic Consensome Meta-Analysis. Thyroid. 2020 04; 30(4):621-639.
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NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPa and inflammatory signaling. Blood. 2018 03 08; 131(10):1081-1093.
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A plurality of molecular targets: The receptor ecosystem for bisphenol-A (BPA). Horm Behav. 2018 05; 101:59-67.
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Role of Thyroxine in the Development of Keratoconus. Cornea. 2016 Oct; 35(10):1338-46.
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Role of co-regulators in metabolic and transcriptional actions of thyroid hormone. J Mol Endocrinol. 2016 04; 56(3):73-97.
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Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat. Cell Rep. 2015 Nov 24; 13(8):1528-37.
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Hepatic FOXO1 Target Genes Are Co-regulated by Thyroid Hormone via RICTOR Protein Deacetylation and MTORC2-AKT Protein Inhibition. J Biol Chem. 2016 Jan 01; 291(1):198-214.
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Structural mechanism for signal transduction in RXR nuclear receptor heterodimers. Nat Commun. 2015 Aug 20; 6:8013.
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Nuclear receptor 4A (NR4A) family - orphans no more. J Steroid Biochem Mol Biol. 2016 Mar; 157:48-60.
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NCoR1 and SMRT play unique roles in thyroid hormone action in vivo. Mol Cell Biol. 2015 Feb; 35(3):555-65.