Thyroid Hormone Receptors beta
"Thyroid Hormone Receptors beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
| Descriptor ID |
D037042
|
| MeSH Number(s) |
D12.776.624.664.700.830.750 D12.776.826.850.750
|
| Concept/Terms |
Thyroid Hormone Receptors beta- Thyroid Hormone Receptors beta
- TR beta
- Thyroid Hormone Receptor beta
- ERBA2 Gene Products
- Gene Products, ERBA2
- NR1A2 Gene Products
- Gene Products, NR1A2
- Receptors beta, Thyroid Hormone
- c-erbA beta
- c erbA beta
- THRB Gene Products
- Gene Products, THRB
|
Below are MeSH descriptors whose meaning is more general than "Thyroid Hormone Receptors beta".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Hormone Receptors beta".
This graph shows the total number of publications written about "Thyroid Hormone Receptors beta" by people in this website by year, and whether "Thyroid Hormone Receptors beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thyroid Hormone Receptors beta" by people in Profiles.
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NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):E8458-E8467.
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Ligand Independent and Subtype-Selective Actions of Thyroid Hormone Receptors in Human Adipose Derived Stem Cells. PLoS One. 2016; 11(10):e0164407.
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Targeting thyroid hormone receptor beta in triple-negative breast cancer. Breast Cancer Res Treat. 2015 Apr; 150(3):535-45.
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Aberrant Monoaminergic System in Thyroid Hormone Receptor-? Deficient Mice as a Model of Attention-Deficit/Hyperactivity Disorder. Int J Neuropsychopharmacol. 2015 Jan 22; 18(7):pyv004.
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Thyroid hormone receptor regulates most genes independently of fibroblast growth factor 21 in liver. J Endocrinol. 2015 Mar; 224(3):289-301.
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Hepatic nuclear corepressor 1 regulates cholesterol absorption through a TR?1-governed pathway. J Clin Invest. 2014 May; 124(5):1976-86.
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Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors. Mol Cell Biol. 2014 May; 34(9):1564-75.
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Thyroid hormone receptor agonists reduce serum cholesterol independent of the LDL receptor. Endocrinology. 2012 Dec; 153(12):6136-44.
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Maternal high-fat diet modulates the fetal thyroid axis and thyroid gene expression in a nonhuman primate model. Mol Endocrinol. 2012 Dec; 26(12):2071-80.
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Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1). Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17462-7.