Retinoblastoma-Like Protein p130
"Retinoblastoma-Like Protein p130" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
| Descriptor ID |
D050717
|
| MeSH Number(s) |
D12.776.624.776.735 D12.776.660.794 D12.776.744.755
|
| Concept/Terms |
Retinoblastoma-Like Protein p130- Retinoblastoma-Like Protein p130
- p130, Retinoblastoma-Like Protein
- Retinoblastoma Like Protein p130
- Retinoblastoma-Like Protein 2
- Retinoblastoma Like Protein 2
- RBL2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Retinoblastoma-Like Protein p130".
Below are MeSH descriptors whose meaning is more specific than "Retinoblastoma-Like Protein p130".
This graph shows the total number of publications written about "Retinoblastoma-Like Protein p130" by people in this website by year, and whether "Retinoblastoma-Like Protein p130" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
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Below are the most recent publications written about "Retinoblastoma-Like Protein p130" by people in Profiles.
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Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR. Nat Genet. 2014 Jan; 46(1):39-44.
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miR-106a represses the Rb tumor suppressor p130 to regulate cellular proliferation and differentiation in high-grade serous ovarian carcinoma. Mol Cancer Res. 2013 Nov; 11(11):1314-25.
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Expression of the retinoblastoma-related gene Rb2/p130 in the pathogenesis of serous carcinoma of the ovary. Appl Immunohistochem Mol Morphol. 2010 Dec; 18(6):509-11.
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Overexpression of E2F5/p130, but not E2F5 alone, can inhibit E2F-induced cell cycle entry in transgenic mice. Mol Vis. 2008 Mar 25; 14:602-14.
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A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol. 2008 Mar; 15(3):268-79.
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Effects of granulosa cell-specific deletion of Rb in Inha-alpha null female mice. Endocrinology. 2007 Aug; 148(8):3837-49.
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p130Rb2 and p27kip1 cooperate to control mobilization of angiogenic progenitors from the bone marrow. Proc Natl Acad Sci U S A. 2005 May 10; 102(19):6890-5.
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Growth factors and receptors in juvenile nasopharyngeal angiofibroma and nasal polyps: an immunohistochemical study. Arch Pathol Lab Med. 2003 Nov; 127(11):1480-4.
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Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle. 2003 Jul-Aug; 2(4):339-45.
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Focal adhesions and associated proteins in medullary thyroid carcinoma cells. J Surg Res. 2003 May 15; 111(2):177-84.