"Wnt1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A proto-oncogene protein and member of the Wnt family of proteins. It is expressed in the caudal MIDBRAIN and is essential for proper development of the entire mid-/hindbrain region.
| Descriptor ID |
D051155
|
| MeSH Number(s) |
D12.776.467.984.100 D12.776.624.664.700.967 D23.529.984.100
|
| Concept/Terms |
Wnt1 Protein- Wnt1 Protein
- Wnt1 Proto-Oncogene Protein
- Proto-Oncogene Protein, Wnt1
- Wnt1 Proto Oncogene Protein
- Proto-Oncogene Protein Wnt-1
- Proto Oncogene Protein Wnt 1
- Wnt-1, Proto-Oncogene Protein
- Wnt-1 Protein
- Wnt 1 Protein
- c-int Protein
- Proto-Oncogene Protein Int-1
- Int-1, Proto-Oncogene Protein
- Proto Oncogene Protein Int 1
|
Below are MeSH descriptors whose meaning is more general than "Wnt1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Wnt1 Protein".
This graph shows the total number of publications written about "Wnt1 Protein" by people in this website by year, and whether "Wnt1 Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 5 | 5 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 5 | 5 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 1 | 1 | 2 |
| 2006 | 3 | 1 | 4 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 3 | 0 | 3 |
| 2010 | 3 | 3 | 6 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2019 | 3 | 0 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Wnt1 Protein" by people in Profiles.
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Loss of IRF2BPL impairs neuronal maintenance through excess Wnt signaling. Sci Adv. 2022 01 21; 8(3):eabl5613.
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RERE deficiency contributes to the development of orofacial clefts in humans and mice. Hum Mol Genet. 2021 05 12; 30(7):595-602.
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The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor. Dis Model Mech. 2019 07 05; 12(7).
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GPNMB augments Wnt-1 mediated breast tumor initiation and growth by enhancing PI3K/AKT/mTOR pathway signaling and ?-catenin activity. Oncogene. 2019 06; 38(26):5294-5307.
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Analysis of the wnt1 regulatory chromosomal landscape. Dev Genes Evol. 2019 05; 229(2-3):43-52.
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Mammary Precancerous Stem and Non-Stem Cells Evolve into Cancers of Distinct Subtypes. Cancer Res. 2019 01 01; 79(1):61-71.
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Heterozygous WNT1 variant causing a variable bone phenotype. Am J Med Genet A. 2018 11; 176(11):2419-2424.
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c-Cbl Expression Correlates with Human Colorectal Cancer Survival and Its Wnt/?-Catenin Suppressor Function Is Regulated by Tyr371 Phosphorylation. Am J Pathol. 2018 08; 188(8):1921-1933.
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Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta-Brief Report. Arterioscler Thromb Vasc Biol. 2017 09; 37(9):1722-1726.
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Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis. J Clin Invest. 2017 Jun 30; 127(7):2678-2688.