"Serum Response Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MADS domain-containing transcription factor that binds to the SERUM RESPONSE ELEMENT in the promoter-enhancer region of many genes. It is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.
| Descriptor ID |
D026362
|
| MeSH Number(s) |
D12.776.260.400.249.875 D12.776.930.397.875
|
| Concept/Terms |
Serum Response Factor- Serum Response Factor
- Response Factor, Serum
- Transcription Factor SRF
- c-fos Serum Response Factor
- c fos Serum Response Factor
|
Below are MeSH descriptors whose meaning is more general than "Serum Response Factor".
Below are MeSH descriptors whose meaning is more specific than "Serum Response Factor".
This graph shows the total number of publications written about "Serum Response Factor" by people in this website by year, and whether "Serum Response Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Serum Response Factor" by people in Profiles.
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Serum response factor is essential for endometrial function and prevention of inflammatory fibrosis. Proc Natl Acad Sci U S A. 2025 Nov 04; 122(44):e2510060122.
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Altered extracellular matrix-related pathways accelerate the transition from normal to prefibroid myometrium in Black women. Am J Obstet Gynecol. 2024 Sep; 231(3):324.e1-324.e12.
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Tbx18 regulates development of the epicardium and coronary vessels. Dev Biol. 2013 Nov 15; 383(2):307-20.
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Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation. 2012 Jun 05; 125(22):2751-61.
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Protein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathway. Mol Cell Biol. 2012 Jan; 32(2):297-308.
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FGFR-4 Arg?88 enhances prostate cancer progression via extracellular signal-related kinase and serum response factor signaling. Clin Cancer Res. 2011 Jul 01; 17(13):4355-66.
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Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17824-9.
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MLK3 limits activated Galphaq signaling to Rho by binding to p63RhoGEF. Mol Cell. 2008 Oct 10; 32(1):43-56.
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Serum response factor micromanaging cardiogenesis. Curr Opin Cell Biol. 2007 Dec; 19(6):618-27.
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Human T-cell leukemia virus type 1 Tax enhances serum response factor DNA binding and alters site selection. J Virol. 2007 Jun; 81(11):6089-98.