 Up-Regulation
"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
| Descriptor ID |
D015854
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| MeSH Number(s) |
G02.111.905 G05.308.850 G07.690.773.998
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| Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
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Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1992 | 0 | 5 | 5 | | 1993 | 0 | 10 | 10 | | 1994 | 0 | 5 | 5 | | 1995 | 1 | 6 | 7 | | 1996 | 1 | 11 | 12 | | 1997 | 0 | 10 | 10 | | 1998 | 2 | 10 | 12 | | 1999 | 2 | 15 | 17 | | 2000 | 2 | 14 | 16 | | 2001 | 1 | 38 | 39 | | 2002 | 5 | 44 | 49 | | 2003 | 4 | 71 | 75 | | 2004 | 6 | 80 | 86 | | 2005 | 8 | 78 | 86 | | 2006 | 8 | 67 | 75 | | 2007 | 7 | 51 | 58 | | 2008 | 5 | 68 | 73 | | 2009 | 5 | 76 | 81 | | 2010 | 7 | 57 | 64 | | 2011 | 13 | 81 | 94 | | 2012 | 14 | 71 | 85 | | 2013 | 10 | 69 | 79 | | 2014 | 8 | 66 | 74 | | 2015 | 6 | 45 | 51 | | 2016 | 3 | 46 | 49 | | 2017 | 8 | 48 | 56 | | 2018 | 4 | 33 | 37 | | 2019 | 1 | 3 | 4 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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Fu C, Xu X, Lu W, Nie L, Yin T, Wu D. Increased expression of long non-coding RNA CCAT2 predicts poorer prognosis in patients with hepatocellular carcinoma. Medicine (Baltimore). 2019 Oct; 98(42):e17412.
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Luo J, Wang K, Yeh S, Sun Y, Liang L, Xiao Y, Xu W, Niu Y, Cheng L, Maity SN, Jiang R, Chang C. LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling. Nat Commun. 2019 06 12; 10(1):2571.
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Moreno-Villanueva M, Zhang Y, Feiveson A, Mistretta B, Pan Y, Chatterjee S, Wu W, Clanton R, Nelman-Gonzalez M, Krieger S, Gunaratne P, Crucian B, Wu H. Single-Cell RNA-Sequencing Identifies Activation of TP53 and STAT1 Pathways in Human T Lymphocyte Subpopulations in Response to Ex Vivo Radiation Exposure. Int J Mol Sci. 2019 May 10; 20(9).
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Turato C, Scarpa M, Kotsafti A, Cappon A, Quarta S, Biasiolo A, Cavallin F, Trevellin E, Guzzardo V, Fassan M, Chiarion-Sileni V, Castoro C, Rugge M, Vettor R, Scarpa M, Pontisso P. Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity. Cancer Sci. 2019 May; 110(5):1552-1563.
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Bedolla RG, Shah DP, Huang SB, Reddick RL, Ghosh R, Kumar AP. Receptor tyrosine kinase recepteur d'origine nantais as predictive marker for aggressive prostate cancer in African Americans. Mol Carcinog. 2019 06; 58(6):854-861.
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Lü JM, Jiang J, Jamaluddin MS, Liang Z, Yao Q, Chen C. Ginsenoside Rb1 Blocks Ritonavir-Induced Oxidative Stress and eNOS Downregulation through Activation of Estrogen Receptor-Beta and Upregulation of SOD in Human Endothelial Cells. Int J Mol Sci. 2019 Jan 12; 20(2).
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Diniz MG, França JA, Vilas-Boas FAS, de Souza FTA, Calin GA, Gomez RS, de Sousa SF, Gomes CC. The long noncoding RNA KIAA0125 is upregulated in ameloblastomas. Pathol Res Pract. 2019 Mar; 215(3):466-469.
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Bhardwaj A, Singh H, Trinidad CM, Albarracin CT, Hunt KK, Bedrosian I. The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer. Breast Cancer Res. 2018 12 11; 20(1):150.
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Mohanty A, Sandoval N, Phan A, Nguyen TV, Chen RW, Budde E, Mei M, Popplewell L, Pham LV, Kwak LW, Weisenburger DD, Rosen ST, Chan WC, Müschen M, Ngo VN. Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma. Blood. 2019 01 24; 133(4):306-318.
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Litvinchuk A, Wan YW, Swartzlander DB, Chen F, Cole A, Propson NE, Wang Q, Zhang B, Liu Z, Zheng H. Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease. Neuron. 2018 12 19; 100(6):1337-1353.e5.
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