"Drug Resistance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Diminished or failed response of an organism, disease or tissue to the intended effectiveness of a chemical or drug. It should be differentiated from DRUG TOLERANCE which is the progressive diminution of the susceptibility of a human or animal to the effects of a drug, as a result of continued administration.
| Descriptor ID |
D004351
|
| MeSH Number(s) |
G07.690.773.984
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Drug Resistance".
Below are MeSH descriptors whose meaning is more specific than "Drug Resistance".
This graph shows the total number of publications written about "Drug Resistance" by people in this website by year, and whether "Drug Resistance" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 5 | 5 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 5 | 5 |
| 1999 | 1 | 4 | 5 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 7 | 7 |
| 2002 | 1 | 6 | 7 |
| 2003 | 0 | 6 | 6 |
| 2004 | 1 | 4 | 5 |
| 2005 | 3 | 4 | 7 |
| 2006 | 2 | 3 | 5 |
| 2007 | 0 | 4 | 4 |
| 2008 | 3 | 4 | 7 |
| 2009 | 5 | 8 | 13 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 4 | 4 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 7 | 9 |
| 2014 | 2 | 4 | 6 |
| 2015 | 0 | 3 | 3 |
| 2016 | 0 | 4 | 4 |
| 2017 | 3 | 3 | 6 |
| 2018 | 3 | 3 | 6 |
| 2019 | 2 | 7 | 9 |
| 2020 | 4 | 5 | 9 |
| 2021 | 1 | 3 | 4 |
| 2023 | 1 | 1 | 2 |
| 2024 | 1 | 3 | 4 |
| 2025 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Drug Resistance" by people in Profiles.
-
Differential ex vivo susceptibility of Plasmodium malariae and Plasmodium falciparum clinical isolates from Ghana and Mali to current and lead discovery candidate antimalarial drugs. Microbiol Spectr. 2025 Apr; 13(4):e0217624.
-
A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria. Science. 2024 09 27; 385(6716):eadm7966.
-
A Multicenter Evaluation of Clopidogrel Resistance and Its Role in Predicting Stent Thrombosis in Transcarotid Artery Revascularization. Ann Vasc Surg. 2025 Jan; 110(Pt A):226-232.
-
Medication refractory restless legs syndrome: Real-world experience. J Neurol Sci. 2024 Aug 15; 463:123121.
-
Leishmania donovani mitogen-activated protein kinases as a host-parasite interaction interface. Cytokine. 2024 07; 179:156627.
-
A novel mutation in mitochondrial cytochrome b conferring resistance to bifenazate in two-spotted spider mite Tetranychus urticae Koch (Acarina: Tetranychidae). Pest Manag Sci. 2024 Jul; 80(7):3612-3619.
-
Review article: new treatments for advanced differentiated thyroid cancers and potential mechanisms of drug resistance. Front Endocrinol (Lausanne). 2023; 14:1176731.
-
Novel Agents in Waldenstr?m Macroglobulinemia. Hematol Oncol Clin North Am. 2023 08; 37(4):751-760.
-
Mutagenesis and structural analysis reveal the CTX-M ?-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J Biol Chem. 2023 05; 299(5):104630.
-
PMCA inhibition reverses drug resistance in clinically refractory cancer patient-derived models. BMC Med. 2023 02 01; 21(1):38.