Nucleic Acid Hybridization
"Nucleic Acid Hybridization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Widely used technique which exploits the ability of complementary sequences in single-stranded DNAs or RNAs to pair with each other to form a double helix. Hybridization can take place between two complimentary DNA sequences, between a single-stranded DNA and a complementary RNA, or between two RNA sequences. The technique is used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands. (Kendrew, Encyclopedia of Molecular Biology, 1994, p503)
| Descriptor ID |
D009693
|
| MeSH Number(s) |
E05.393.661 G02.111.611
|
| Concept/Terms |
Nucleic Acid Hybridization- Nucleic Acid Hybridization
- Acid Hybridization, Nucleic
- Acid Hybridizations, Nucleic
- Hybridization, Nucleic Acid
- Hybridizations, Nucleic Acid
- Nucleic Acid Hybridizations
Genomic Hybridization- Genomic Hybridization
- Genomic Hybridizations
- Hybridization, Genomic
- Hybridizations, Genomic
|
Below are MeSH descriptors whose meaning is more general than "Nucleic Acid Hybridization".
Below are MeSH descriptors whose meaning is more specific than "Nucleic Acid Hybridization".
This graph shows the total number of publications written about "Nucleic Acid Hybridization" by people in this website by year, and whether "Nucleic Acid Hybridization" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 3 | 4 |
| 1997 | 0 | 3 | 3 |
| 1998 | 1 | 3 | 4 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 3 | 4 |
| 2001 | 1 | 5 | 6 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 7 | 7 |
| 2004 | 1 | 11 | 12 |
| 2005 | 4 | 4 | 8 |
| 2006 | 3 | 3 | 6 |
| 2007 | 8 | 9 | 17 |
| 2008 | 4 | 5 | 9 |
| 2009 | 0 | 4 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Nucleic Acid Hybridization" by people in Profiles.
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Mechanism, prevalence, and more severe neuropathy phenotype of the Charcot-Marie-Tooth type 1A triplication. Am J Hum Genet. 2014 Mar 06; 94(3):462-9.
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Real-time monitoring of DNA hybridization and melting processes using a fiber optic sensor. Nanotechnology. 2012 Feb 17; 23(6):065503.
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Rare target enrichment for ultrasensitive PCR detection using cot-rehybridization and duplex-specific nuclease. Anal Biochem. 2012 Feb 01; 421(1):81-5.
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Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis. Proc Natl Acad Sci U S A. 2011 Oct 18; 108(42):17456-61.
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Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to Mexico. Clin Infect Dis. 2011 Jun; 52(11):1332-41.
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R loops stimulate genetic instability of CTG.CAG repeats. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):692-7.
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Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J Biol Chem. 2009 Oct 02; 284(40):27487-99.
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Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):13033-8.
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Clinical utility of array comparative genomic hybridization for detection of chromosomal abnormalities in pediatric acute lymphoblastic leukemia. Pediatr Blood Cancer. 2008 Aug; 51(2):171-7.
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Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes. Br J Haematol. 2008 Jun; 142(2):216-26.