| Item Type | Name |
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Academic Article
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Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells.
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Academic Article
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Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
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Academic Article
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SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization.
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Concept
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Hepatocyte Growth Factor
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Concept
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Vascular Endothelial Growth Factor C
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Concept
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Eukaryotic Initiation Factor-2
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Concept
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Vascular Endothelial Growth Factor A
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Concept
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TNF Receptor-Associated Factor 6
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Concept
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Transforming Growth Factor beta
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Concept
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Leukemia Inhibitory Factor Receptor alpha Subunit
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Concept
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Insulin-Like Growth Factor I
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Concept
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Vascular Endothelial Growth Factor Receptor-3
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Concept
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Transcription Factor AP-1
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Concept
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Positive Transcriptional Elongation Factor B
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Concept
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Stem Cell Factor
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Concept
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Receptors, Tumor Necrosis Factor, Type I
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Concept
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TNF Receptor-Associated Factor 4
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Concept
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STAT3 Transcription Factor
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Concept
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Receptor, Fibroblast Growth Factor, Type 2
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Concept
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GATA3 Transcription Factor
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Concept
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Epidermal Growth Factor
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Concept
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Sp1 Transcription Factor
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Concept
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Macrophage Colony-Stimulating Factor
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Concept
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Receptors, Fibroblast Growth Factor
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Concept
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Vascular Endothelial Growth Factor Receptor-2
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Concept
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Activating Transcription Factor 3
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Concept
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E2F3 Transcription Factor
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Concept
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Hypoxia-Inducible Factor 1
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Concept
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E2F1 Transcription Factor
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Receptors, Tumor Necrosis Factor
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Concept
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Receptors, Vascular Endothelial Growth Factor
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Concept
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Octamer Transcription Factor-2
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Concept
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Hepatocyte Nuclear Factor 3-beta
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Concept
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SOX9 Transcription Factor
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Concept
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Transcription Factor RelA
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Concept
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Hypoxia-Inducible Factor 1, alpha Subunit
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Concept
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Octamer Transcription Factor-3
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Concept
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Transcription Factor AP-2
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Concept
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Transforming Growth Factor beta1
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Concept
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Insulin-Like Growth Factor Binding Protein 3
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Academic Article
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IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway.
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Academic Article
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Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells.
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Academic Article
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EGFR-SGLT1 interaction does not respond to EGFR modulators, but inhibition of SGLT1 sensitizes prostate cancer cells to EGFR tyrosine kinase inhibitors.
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Academic Article
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A tumorigenic factor interactome connected through tumor suppressor microRNA-198 in human pancreatic cancer.
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Academic Article
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Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis.
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Academic Article
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Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-?-dependent cancer metastasis.
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Academic Article
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Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties.
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Academic Article
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14-3-3? turns TGF-?'s function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2.
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Academic Article
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Length of the linking domain of human pro-tumor necrosis factor determines the cleavage processing.
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Academic Article
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EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization.
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Academic Article
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The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells.
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Academic Article
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Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-kappaB expression.
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Academic Article
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Kr?ppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion.
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Academic Article
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Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression.
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Academic Article
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IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.
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Academic Article
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Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice.
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Academic Article
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Oxygen sensor boosts growth factor signaling.
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Academic Article
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COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport.
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Academic Article
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Rapid detection of two-protein interaction with a single fluorophore by using a microfluidic device.
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Academic Article
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Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells.
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Academic Article
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Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.
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Academic Article
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mMAPS: a flow-proteometric technique to analyze protein-protein interactions in individual signaling complexes.
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Academic Article
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miR326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression.
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Academic Article
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Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis.
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Academic Article
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A new role of protein phosphatase 2a in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells.
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Academic Article
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E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation.
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Academic Article
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Co-regulation of B-Myb expression by E2F1 and EGF receptor.
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Academic Article
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Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death.
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Academic Article
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Further evidence for expression and function of the VEGF-C/VEGFR-3 axis in cancer cells.
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Academic Article
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KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.
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Academic Article
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Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer.
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Academic Article
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Myocyte enhancer factor-2 interacting transcriptional repressor (MITR) is a switch that promotes osteogenesis and inhibits adipogenesis of mesenchymal stem cells by inactivating peroxisome proliferator-activated receptor gamma-2.
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Academic Article
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Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin.
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Academic Article
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Mesenchymal stem cells promote formation of colorectal tumors in mice.
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Academic Article
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Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family.
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Academic Article
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Targeting the IKK?/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer.
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Academic Article
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Lapatinib-mediated cyclooxygenase-2 expression via epidermal growth factor receptor/HuR interaction enhances the aggressiveness of triple-negative breast cancer cells.
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Academic Article
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Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.
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Academic Article
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MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis.
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Academic Article
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Human pro-tumor necrosis factor is a homotrimer.
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Academic Article
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The adenoviral E1A induces p21WAF1/CIP1 expression in cancer cells.
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Academic Article
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Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.
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Academic Article
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Inefficient proteasomal-degradation pathway stabilizes AP-2alpha and activates HER-2/neu gene in breast cancer.
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Academic Article
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Advances in targeting human epidermal growth factor receptor-2 signaling for cancer therapy.
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Academic Article
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Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.
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Academic Article
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Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer.
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Academic Article
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14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition.
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Academic Article
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CARMA3 is crucial for EGFR-Induced activation of NF-?B and tumor progression.
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Academic Article
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IKKa activation of NOTCH links tumorigenesis via FOXA2 suppression.
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Academic Article
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Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway.
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Academic Article
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ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells.
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Academic Article
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Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors.
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Academic Article
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Epithelial-mesenchymal transition induced by TNF-a requires NF-?B-mediated transcriptional upregulation of Twist1.
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Academic Article
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KrasG12D-induced IKK2/?/NF-?B activation by IL-1a and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.
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Academic Article
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Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.
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Academic Article
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LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker.
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Academic Article
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A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells.
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Academic Article
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TNFalpha induces HIF-1alpha expression through activation of IKKbeta.
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Academic Article
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Nuclear trafficking of the epidermal growth factor receptor family membrane proteins.
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Academic Article
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Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells.
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Academic Article
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Novel therapeutic strategy targeting the Hedgehog signalling and mTOR pathways in biliary tract cancer.
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Academic Article
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Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases.
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Academic Article
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Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.
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Academic Article
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Erythropoietin Stimulates Tumor Growth via EphB4.
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Academic Article
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Non-canonical signaling mode of the epidermal growth factor receptor family.
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Academic Article
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Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.
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Academic Article
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Activation of keap1/nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells
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Academic Article
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Non-canonical signaling mode of the epidermal growth factor receptor family
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Academic Article
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A novel alteration in the epidermal growth factor receptor gene is frequently detected in human non-small cell lung cancer
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Academic Article
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Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer.
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Academic Article
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The LINK-A lncRNA activates normoxic HIF1a signalling in triple-negative breast cancer.
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Academic Article
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Severe Hepatitis Promotes Hepatocellular Carcinoma Recurrence via NF-?B Pathway-Mediated Epithelial-Mesenchymal Transition after Resection.
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Academic Article
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Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells.
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Academic Article
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A Positive TGF-?/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer.
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Academic Article
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Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis.
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Academic Article
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Deubiquitination and Stabilization of PD-L1 by CSN5.
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Academic Article
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A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1a activation, tumorigenesis and?metastasis.
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Academic Article
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A UBE2O-AMPKa2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy.
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Academic Article
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HIF-1a promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
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Academic Article
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CDK4/6 inhibitors in hormone receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer: Are we at the finish line?
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Academic Article
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Expression and Clinical Significance of Protein Kinase RNA-Like Endoplasmic Reticulum Kinase and Phosphorylated Eukaryotic Initiation Factor 2a in Pancreatic Ductal Adenocarcinoma.
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Academic Article
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MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.
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Academic Article
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Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFa-induced apoptosis.
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Academic Article
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Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade.
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Concept
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Transcription Factor HES-1
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Concept
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Pre-B-Cell Leukemia Transcription Factor 1
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Concept
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Heparin-binding EGF-like Growth Factor
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Academic Article
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ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis.
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Academic Article
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Hepatoma cell-intrinsic TLR9 activation induces immune escape through PD-L1 upregulation in hepatocellular carcinoma.
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Academic Article
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TRPS1: a highly sensitive and specific marker for breast carcinoma, especially for triple-negative breast cancer.
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Academic Article
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AMBRA1 Promotes TGF? Signaling via Nonproteolytic Polyubiquitylation of Smad4.
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Academic Article
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Endothelial p130cas confers resistance to anti-angiogenesis therapy.
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Academic Article
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Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies.
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Academic Article
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Targeting the ALK-CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex.
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Academic Article
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Nuclear export signal mutation of epidermal growth factor receptor enhances malignant phenotypes of cancer cells.
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Academic Article
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Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer.
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