Vascular Endothelial Growth Factor Receptor-3
"Vascular Endothelial Growth Factor Receptor-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vascular endothelial cell growth factor receptor whose expression is restricted primarily to adult lymphatic endothelium. VEGFR-3 preferentially binds the vascular endothelial growth factor C and vascular endothelial growth factor D and may be involved in the control of lymphangiogenesis.
| Descriptor ID |
D040321
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.950.300 D12.776.543.750.630.750.300 D12.776.543.750.750.400.910.300
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor Receptor-3".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor Receptor-3".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor Receptor-3" by people in this website by year, and whether "Vascular Endothelial Growth Factor Receptor-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 2 | 1 | 3 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor Receptor-3" by people in Profiles.
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S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020 07 23; 5(14).
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Circulating Biomarkers From the Phase 1 Trial of Sirolimus and Autophagy Inhibition for Patients With Lymphangioleiomyomatosis. Chest. 2018 11; 154(5):1070-1082.
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Serum vascular endothelial growth factor receptor 3 as a potential biomarker in psoriasis. Exp Dermatol. 2018 09; 27(9):1053-1057.
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Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 09 18; 8(1):578.
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Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection. J Clin Invest. 2015 Nov 02; 125(11):4255-68.
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Expression of angiopoietin-2 and vascular endothelial growth factor receptor-3 correlates with lymphangiogenesis and angiogenesis and affects survival of oral squamous cell carcinoma. PLoS One. 2013; 8(9):e75388.
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Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity. Blood. 2013 May 16; 121(20):4242-9.
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Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression. Neoplasia. 2012 Mar; 14(3):228-37.
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Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors. Oncogene. 2010 May 20; 29(20):2938-49.
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Vascular endothelial growth factors C and D induces proliferation of lymphangioleiomyomatosis cells through autocrine crosstalk with endothelium. Am J Pathol. 2009 Oct; 175(4):1410-20.