Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
|
| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
|
| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
|
Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 3 | 5 |
| 1996 | 6 | 4 | 10 |
| 1997 | 5 | 2 | 7 |
| 1998 | 3 | 1 | 4 |
| 1999 | 4 | 4 | 8 |
| 2000 | 4 | 7 | 11 |
| 2001 | 7 | 0 | 7 |
| 2002 | 6 | 5 | 11 |
| 2003 | 9 | 3 | 12 |
| 2004 | 5 | 5 | 10 |
| 2005 | 6 | 5 | 11 |
| 2006 | 3 | 7 | 10 |
| 2007 | 5 | 3 | 8 |
| 2008 | 6 | 5 | 11 |
| 2009 | 1 | 4 | 5 |
| 2010 | 4 | 6 | 10 |
| 2011 | 3 | 6 | 9 |
| 2012 | 0 | 3 | 3 |
| 2013 | 2 | 4 | 6 |
| 2014 | 4 | 4 | 8 |
| 2015 | 3 | 2 | 5 |
| 2016 | 2 | 1 | 3 |
| 2017 | 2 | 2 | 4 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 3 | 0 | 3 |
| 2021 | 2 | 0 | 2 |
| 2022 | 0 | 2 | 2 |
| 2023 | 3 | 2 | 5 |
| 2024 | 3 | 2 | 5 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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IGF-1 impacts neocortical interneuron connectivity in epileptic spasm generation and resolution. Neurotherapeutics. 2025 Jan; 22(1):e00477.
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Fluoxetine and Sertraline Inhibit Height Growth and Growth Hormone Signaling During Puberty. J Clin Psychopharmacol. 2024 Nov-Dec; 44(6):538-544.
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Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intake. Geroscience. 2024 Oct; 46(5):4809-4826.
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Evolving growth hormone deficiency: proof of concept. Front Endocrinol (Lausanne). 2024; 15:1398171.
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Challenges of insulin-like growth factor-1 testing. Crit Rev Clin Lab Sci. 2024 Aug; 61(5):388-403.
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Gut development following insulin-like growth factor-1 supplementation to preterm pigs. Pediatr Res. 2024 May; 95(6):1528-1535.
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Delayed skeletal development and IGF-1 deficiency in a mouse model of lysinuric protein intolerance. Dis Model Mech. 2023 08 01; 16(8).
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Hormonal changes in veterans with Gulf War Illness. Life Sci. 2023 Sep 01; 328:121908.
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Insulin-Like Growth Factor-1 Supplementation Promotes Brain Maturation in Preterm Pigs. eNeuro. 2023 04; 10(4).
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Pilot clinical trial of macimorelin to assess safety and efficacy in patients with cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 04; 14(2):835-846.