GATA3 Transcription Factor
"GATA3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is found predominately in LYMPHOID CELL precursors and has been implicated in the CELL DIFFERENTIATION of HELPER T-CELLS. Haploinsufficiency of GATA3 is associated with HYPOPARATHYROIDISM; SENSORINEURAL HEARING LOSS; and renal anomalies syndrome.
| Descriptor ID |
D050990
|
| MeSH Number(s) |
D12.776.260.235.687 D12.776.260.257.300 D12.776.930.216.687 D12.776.930.314.300
|
| Concept/Terms |
GATA3 Transcription Factor- GATA3 Transcription Factor
- Transcription Factor, GATA3
- Transcription Factor GATA3
- GATA3, Transcription Factor
- Nuclear Factor-Erythroid 1C
- Nuclear Factor Erythroid 1C
- GATA-3 Factors
- GATA 3 Factors
- NF-E1C Protein
- NF E1C Protein
|
Below are MeSH descriptors whose meaning is more general than "GATA3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA3 Transcription Factor".
This graph shows the total number of publications written about "GATA3 Transcription Factor" by people in this website by year, and whether "GATA3 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 3 | 4 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 2 | 4 |
| 2022 | 3 | 0 | 3 |
| 2025 | 0 | 1 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "GATA3 Transcription Factor" by people in Profiles.
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GATA3 Is Underexpressed in Penile Neoplasia: Potential Implications in Diagnosis and Pathogenesis. Am J Surg Pathol. 2026 Apr 01; 50(4):416-426.
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N-acetyl-L-alanine ameliorates atopic dermatitis-like symptoms by suppressing Th2 differentiation in DNFB-induced NC/Nga mice. BMB Rep. 2025 Oct; 58(10):437-443.
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14-3-3t drives estrogen receptor loss via ERa36 induction and GATA3 inhibition in breast cancer. Proc Natl Acad Sci U S A. 2022 10 25; 119(43):e2209211119.
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TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma. Hum Pathol. 2022 07; 125:97-107.
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Noncoding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation. Nat Genet. 2022 02; 54(2):170-179.
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The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway. Mol Cell Biol. 2021 08 24; 41(9):e0008521.
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Cell lineage tracing links ERa loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype. Proc Natl Acad Sci U S A. 2021 05 25; 118(21).
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Acinic Cell Carcinoma of the Breast: Report of a Case With Immunohistochemical and Next-Generation Sequencing Studies. Int J Surg Pathol. 2021 Dec; 29(8):882-886.
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Association of GATA3 Polymorphisms With Minimal Residual Disease and Relapse Risk in Childhood Acute Lymphoblastic Leukemia. J Natl Cancer Inst. 2021 04 06; 113(4):408-417.
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Extramammary Paget Disease of the Scrotum: A Contemporary Clinicopathologic Analysis of 20 Cases in the United States. Appl Immunohistochem Mol Morphol. 2020 08; 28(7):524-531.