GATA4 Transcription Factor
"GATA4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is expressed in the MYOCARDIUM of developing heart and has been implicated in the differentiation of CARDIAC MYOCYTES. GATA4 is activated by PHOSPHORYLATION and regulates transcription of cardiac-specific genes.
Descriptor ID |
D050991
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MeSH Number(s) |
D12.776.260.257.400 D12.776.930.314.400
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Concept/Terms |
GATA4 Transcription Factor- GATA4 Transcription Factor
- Transcription Factor, GATA4
- Transcription Factor GATA-4
- Factor GATA-4, Transcription
- GATA-4, Transcription Factor
- Transcription Factor GATA 4
- Transcription Factor GATA4
- Factor GATA4, Transcription
- GATA4, Transcription Factor
- GATA-4 Transcription Factor
- GATA 4 Transcription Factor
- Transcription Factor, GATA-4
|
Below are MeSH descriptors whose meaning is more general than "GATA4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA4 Transcription Factor".
This graph shows the total number of publications written about "GATA4 Transcription Factor" by people in this website by year, and whether "GATA4 Transcription Factor" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 2 | 2 |
2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 3 | 0 | 3 |
2012 | 0 | 2 | 2 |
2013 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 4 | 5 |
2016 | 1 | 1 | 2 |
2017 | 1 | 0 | 1 |
2018 | 2 | 0 | 2 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "GATA4 Transcription Factor" by people in Profiles.
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A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network. Circulation. 2024 Apr 09; 149(15):1205-1230.
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Gata4-Dependent Differentiation of c-Kit+-Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart. Circulation. 2018 09 04; 138(10):1012-1024.
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RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects. Dis Model Mech. 2018 08 28; 11(9).
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Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program. Genes Dev. 2017 10 01; 31(19):1933-1938.
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Cardiac reprogramming factor Gata4 reduces postinfarct cardiac fibrosis through direct repression of the profibrotic mediator snail. J Thorac Cardiovasc Surg. 2017 11; 154(5):1601-1610.e3.
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MiR-590 Promotes Transdifferentiation of Porcine and Human Fibroblasts Toward a Cardiomyocyte-Like Fate by Directly Repressing Specificity Protein 1. J Am Heart Assoc. 2016 11 10; 5(11).
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How autophagy both activates and inhibits cellular senescence. Autophagy. 2016 05 03; 12(5):898-9.
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Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis. Cell. 2016 Feb 25; 164(5):999-1014.
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GATA4 and GATA6 Knockdown During Luteinization Inhibits Progesterone Production and Gonadotropin Responsiveness in the Corpus Luteum of Female Mice. Biol Reprod. 2015 Dec; 93(6):133.
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Low-dose radiation affects cardiac physiology: gene networks and molecular signaling in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2015 Dec 01; 309(11):H1947-63.