GATA4 Transcription Factor
"GATA4 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GATA transcription factor that is expressed in the MYOCARDIUM of developing heart and has been implicated in the differentiation of CARDIAC MYOCYTES. GATA4 is activated by PHOSPHORYLATION and regulates transcription of cardiac-specific genes.
| Descriptor ID |
D050991
|
| MeSH Number(s) |
D12.776.260.257.400 D12.776.930.314.400
|
| Concept/Terms |
GATA4 Transcription Factor- GATA4 Transcription Factor
- Transcription Factor, GATA4
- Transcription Factor GATA-4
- Factor GATA-4, Transcription
- GATA-4, Transcription Factor
- Transcription Factor GATA 4
- Transcription Factor GATA4
- Factor GATA4, Transcription
- GATA4, Transcription Factor
- GATA-4 Transcription Factor
- GATA 4 Transcription Factor
- Transcription Factor, GATA-4
|
Below are MeSH descriptors whose meaning is more general than "GATA4 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "GATA4 Transcription Factor".
This graph shows the total number of publications written about "GATA4 Transcription Factor" by people in this website by year, and whether "GATA4 Transcription Factor" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 3 | 4 |
| 2016 | 2 | 2 | 4 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "GATA4 Transcription Factor" by people in Profiles.
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Sall4 and Gata4 induce cardiac fibroblast transition towards a partially multipotent state with cardiogenic potential. Sci Rep. 2024 10 15; 14(1):24182.
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A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network. Circulation. 2024 Apr 09; 149(15):1205-1230.
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Intrinsic activation of cardiosphere-derived cells enhances myocardial repair. J Thorac Cardiovasc Surg. 2022 Apr; 163(4):1479-1490.e5.
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Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming. Cell Stem Cell. 2019 07 03; 25(1):87-102.e9.
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Gata4-Dependent Differentiation of c-Kit+-Derived Endothelial Cells Underlies Artefactual Cardiomyocyte Regeneration in the Heart. Circulation. 2018 09 04; 138(10):1012-1024.
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RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects. Dis Model Mech. 2018 08 28; 11(9).
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Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program. Genes Dev. 2017 10 01; 31(19):1933-1938.
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Cardiac reprogramming factor Gata4 reduces postinfarct cardiac fibrosis through direct repression of the profibrotic mediator snail. J Thorac Cardiovasc Surg. 2017 11; 154(5):1601-1610.e3.
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Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis. Cell. 2016 Dec 15; 167(7):1734-1749.e22.
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Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming. Circulation. 2017 Mar 07; 135(10):978-995.