Inefficient proteasomal-degradation pathway stabilizes AP-2alpha and activates HER-2/neu gene in breast cancer.

Inefficient proteasomal-degradation pathway stabilizes AP-2alpha and activates HER-2/neu gene in breast cancer. Int J Cancer. 2006 Feb 15; 118(4):802-11.

View in: PubMed

subject areas

Animals
Breast Neoplasms
Cell Transformation, Neoplastic
Cysteine Proteinase Inhibitors
Female
Gene Amplification
Gene Expression Regulation
Gene Expression Regulation, Neoplastic
Humans
Leupeptins
Mammary Neoplasms, Animal
Mice
Promoter Regions, Genetic
Proteasome Endopeptidase Complex
Receptor, ErbB-2
Transcription Factor AP-2
Tumor Cells, Cultured
Ubiquitin
Up-Regulation

authors with profiles

MIEN-CHIE HUNG