Cysteine Proteinase Inhibitors
"Cysteine Proteinase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Exogenous and endogenous compounds which inhibit CYSTEINE ENDOPEPTIDASES.
| Descriptor ID |
D015853
|
| MeSH Number(s) |
D27.505.519.389.745.325
|
| Concept/Terms |
Cysteine Proteinase Inhibitors- Cysteine Proteinase Inhibitors
- Inhibitors, Cysteine Proteinase
- Proteinase Inhibitors, Cysteine
- Cysteine Protease Inhibitors
- Inhibitors, Cysteine Protease
- Protease Inhibitors, Cysteine
- Cysteine Proteinase Antagonists
- Antagonists, Cysteine Proteinase
- Proteinase Antagonists, Cysteine
alpha-Cysteine Protease Inhibitors- alpha-Cysteine Protease Inhibitors
- Inhibitors, alpha-Cysteine Protease
- Protease Inhibitors, alpha-Cysteine
- alpha Cysteine Protease Inhibitors
|
Below are MeSH descriptors whose meaning is more general than "Cysteine Proteinase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cysteine Proteinase Inhibitors".
This graph shows the total number of publications written about "Cysteine Proteinase Inhibitors" by people in this website by year, and whether "Cysteine Proteinase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 2 | 4 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 3 | 3 |
| 2012 | 0 | 2 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cysteine Proteinase Inhibitors" by people in Profiles.
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Inhibitors of Coronavirus 3CL Proteases Protect Cells from Protease-Mediated Cytotoxicity. J Virol. 2021 06 24; 95(14):e0237420.
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Stability and pharmacokinetics of separase inhibitor-Sepin-1 in Sprague-Dawley rats. Biochem Pharmacol. 2020 04; 174:113808.
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Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments. Bioorg Med Chem Lett. 2019 01 01; 29(1):36-39.
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TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins. Nat Commun. 2018 07 16; 9(1):2731.
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Therapeutic effect of Schistosoma japonicum cystatin on bacterial sepsis in mice. Parasit Vectors. 2017 May 08; 10(1):222.
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Identification of non-peptidic cysteine reactive fragments as inhibitors of cysteine protease rhodesain. Bioorg Med Chem Lett. 2015 Oct 15; 25(20):4509-12.
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Antithrombin nanoparticles improve kidney reperfusion and protect kidney function after ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2015 Apr 01; 308(7):F765-73.
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Critical roles of Clostridium difficile toxin B enzymatic activities in pathogenesis. Infect Immun. 2015 Feb; 83(2):502-13.
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Vaccination with a genetically modified Brugia malayi cysteine protease inhibitor-2 reduces adult parasite numbers and affects the fertility of female worms following a subcutaneous challenge of Mongolian gerbils (Meriones unguiculatus) with B. malayi infective larvae. Int J Parasitol. 2014 Sep; 44(10):675-9.
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A fragment-based method to discover irreversible covalent inhibitors of cysteine proteases. J Med Chem. 2014 Jun 12; 57(11):4969-74.