E2F3 Transcription Factor
"E2F3 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F3 regulates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.
| Descriptor ID |
D050699
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| MeSH Number(s) |
D12.776.930.211.750
|
| Concept/Terms |
E2F3 Transcription Factor- E2F3 Transcription Factor
- Transcription Factor, E2F3
- Transcription Factor E2F-3
- E2F-3, Transcription Factor
- Transcription Factor E2F 3
- E2F Transcription Factor 3 Protein
|
Below are MeSH descriptors whose meaning is more general than "E2F3 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F3 Transcription Factor".
This graph shows the total number of publications written about "E2F3 Transcription Factor" by people in this website by year, and whether "E2F3 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 4 | 4 |
| 2006 | 1 | 0 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "E2F3 Transcription Factor" by people in Profiles.
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Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies. Proc Natl Acad Sci U S A. 2022 04 19; 119(16):e2117857119.
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p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation. Cell Cycle. 2012 Sep 15; 11(18):3433-42.
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E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol. 2010 Jan; 30(2):524-36.
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Transgenic expression of E2F3a causes DNA damage leading to ATM-dependent apoptosis. Oncogene. 2008 Aug 21; 27(36):4954-61.
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Evaluation of biological pathways involved in chemotherapy response in breast cancer. Breast Cancer Res. 2008; 10(2):R37.
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Overexpression of E2F5/p130, but not E2F5 alone, can inhibit E2F-induced cell cycle entry in transgenic mice. Mol Vis. 2008 Mar 25; 14:602-14.
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E2F3a stimulates proliferation, p53-independent apoptosis and carcinogenesis in a transgenic mouse model. Cell Cycle. 2006 Jan; 5(2):184-90.
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A role for 14-3-3 tau in E2F1 stabilization and DNA damage-induced apoptosis. J Biol Chem. 2004 Dec 24; 279(52):54140-52.
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Transcription factor E2F3 overexpressed in prostate cancer independently predicts clinical outcome. Oncogene. 2004 Aug 05; 23(35):5871-9.
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TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival. Genes Dev. 2004 Mar 15; 18(6):673-86.