E2F2 Transcription Factor
"E2F2 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A. E2F2 activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis.
| Descriptor ID |
D050703
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| MeSH Number(s) |
D12.776.930.211.625
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| Concept/Terms |
E2F2 Transcription Factor- E2F2 Transcription Factor
- Transcription Factor, E2F2
- Transcription Factor E2F-2
- E2F-2, Transcription Factor
- Transcription Factor E2F 2
- E2F Transcription Factor 2 Protein
- E2F2 Protein
- E2F-2 Protein
|
Below are MeSH descriptors whose meaning is more general than "E2F2 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "E2F2 Transcription Factor".
This graph shows the total number of publications written about "E2F2 Transcription Factor" by people in this website by year, and whether "E2F2 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
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Below are the most recent publications written about "E2F2 Transcription Factor" by people in Profiles.
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E2F transcription factor 2 variants as predictive biomarkers for recurrence risk in patients with squamous cell carcinoma of the oropharynx. Mol Carcinog. 2017 04; 56(4):1335-1343.
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A gene expression signature of retinoblastoma loss-of-function is a predictive biomarker of resistance to palbociclib in breast cancer cell lines and is prognostic in patients with ER positive early breast cancer. Oncotarget. 2016 09 13; 7(42):68012-68022.
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Liver ? receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism. Breast Cancer Res. 2013 Jun 20; 15(3):R51.
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The complex containing Drosophila Myb and RB/E2F2 regulates cytokinesis in a histone H2Av-dependent manner. Mol Cell Biol. 2013 May; 33(9):1809-18.
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Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck. Mol Carcinog. 2012 Oct; 51 Suppl 1:E132-41.
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Expression signature of E2F1 and its associated genes predict superficial to invasive progression of bladder tumors. J Clin Oncol. 2010 Jun 01; 28(16):2660-7.
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E2F2 suppresses Myc-induced proliferation and tumorigenesis. Mol Carcinog. 2010 Feb; 49(2):152-6.
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E2F3 is a mediator of DNA damage-induced apoptosis. Mol Cell Biol. 2010 Jan; 30(2):524-36.
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E2F1 in gliomas: a paradigm of oncogene addiction. Cancer Lett. 2008 May 18; 263(2):157-63.
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Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex. Genes Dev. 2008 Mar 01; 22(5):601-14.