Transcription Factor RelA
"Transcription Factor RelA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subunit of NF-kappa B that is primarily responsible for its transactivation function. It contains a C-terminal transactivation domain and an N-terminal domain with homology to PROTO-ONCOGENE PROTEINS C-REL.
| Descriptor ID |
D051996
|
| MeSH Number(s) |
D12.776.260.600.249 D12.776.660.600.249 D12.776.930.600.249
|
| Concept/Terms |
Transcription Factor RelA- Transcription Factor RelA
- RelA, Transcription Factor
- NF-kappa B p65
- NF kappa B p65
- p65, NF-kappa B
- NF-kappa B p65 Subunit
- NF kappa B p65 Subunit
- Transcription Factor p65
- p65, Transcription Factor
- p65 Transcription Factor
- Transcription Factor, p65
- v-Rel Reticuloendotheliosis Viral Oncogene Homolog A
- v Rel Reticuloendotheliosis Viral Oncogene Homolog A
- NF-kappaB 65-kDa
- NF kappaB 65 kDa
|
Below are MeSH descriptors whose meaning is more general than "Transcription Factor RelA".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor RelA".
This graph shows the total number of publications written about "Transcription Factor RelA" by people in this website by year, and whether "Transcription Factor RelA" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 4 | 4 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 5 | 5 |
| 2005 | 2 | 3 | 5 |
| 2006 | 2 | 4 | 6 |
| 2007 | 0 | 3 | 3 |
| 2008 | 1 | 8 | 9 |
| 2009 | 1 | 6 | 7 |
| 2010 | 2 | 5 | 7 |
| 2011 | 3 | 1 | 4 |
| 2012 | 4 | 3 | 7 |
| 2013 | 3 | 3 | 6 |
| 2014 | 2 | 5 | 7 |
| 2015 | 2 | 5 | 7 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 2 | 2 | 4 |
| 2019 | 1 | 2 | 3 |
| 2020 | 2 | 3 | 5 |
| 2021 | 2 | 2 | 4 |
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Below are the most recent publications written about "Transcription Factor RelA" by people in Profiles.
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Bortezomib is significantly beneficial for de novo pediatric AML patients with low phosphorylation of the NF-?B subunit RelA. Proteomics Clin Appl. 2022 03; 16(2):e2100072.
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A novel missense mutation in TNFAIP3 causes haploinsufficiency of A20. Cell Immunol. 2022 01; 371:104453.
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NF-?B p65 regulates hepatic lipogenesis by promoting nuclear entry of ChREBP in response to a high carbohydrate diet. J Biol Chem. 2021 Jan-Jun; 296:100714.
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ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma. Cancer Discov. 2021 09; 11(9):2200-2215.
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NF-?B Blockade by NEMO Binding Domain Peptide Ameliorates Inflammation and Neurobehavioral Sequelae After Cranial Radiation Therapy in Juvenile Mice. Int J Radiat Oncol Biol Phys. 2021 04 01; 109(5):1508-1520.
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Morusin induces apoptosis and autophagy via JNK, ERK and PI3K/Akt signaling in human lung carcinoma cells. Chem Biol Interact. 2020 Nov 01; 331:109279.
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Low-dose naltrexone rescues inflammation and insulin resistance associated with hyperinsulinemia. J Biol Chem. 2020 11 27; 295(48):16359-16369.
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Role of SIRT1 in HIV-associated kidney disease. Am J Physiol Renal Physiol. 2020 08 01; 319(2):F335-F344.
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The overexpression of long intergenic ncRNA00162 induced by RelA/p65 promotes growth of pancreatic ductal adenocarcinoma. Cell Prolif. 2020 May; 53(5):e12805.
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RELA is sufficient to mediate interleukin-1 repression of androgen receptor expression and activity in an LNCaP disease progression model. Prostate. 2020 02; 80(2):133-145.