"NF-kappa B p50 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses.
| Descriptor ID |
D052002
|
| MeSH Number(s) |
D12.776.260.600.124 D12.776.660.600.124 D12.776.930.600.124
|
| Concept/Terms |
NF-kappa B p50 Subunit- NF-kappa B p50 Subunit
- NF kappa B p50 Subunit
- NFKB1 Transcription Factor
- Transcription Factor, NFKB1
- NF-kappa B p50
- NF kappa B p50
- p50, NF-kappa B
- NF-kappaB 50-kDa
- NF kappaB 50 kDa
|
Below are MeSH descriptors whose meaning is more general than "NF-kappa B p50 Subunit".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B p50 Subunit".
This graph shows the total number of publications written about "NF-kappa B p50 Subunit" by people in this website by year, and whether "NF-kappa B p50 Subunit" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "NF-kappa B p50 Subunit" by people in Profiles.
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a-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014 Mar; 16(3):245-54.
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Prognostic value of single nucleotide polymorphisms of candidate genes associated with inflammation in early stage breast cancer. Breast Cancer Res Treat. 2013 Apr; 138(3):917-24.
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FOXM1 mediates Dox resistance in breast cancer by enhancing DNA repair. Carcinogenesis. 2012 Oct; 33(10):1843-53.
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The specificity of innate immune responses is enforced by repression of interferon response elements by NF-?B p50. Sci Signal. 2011 Feb 22; 4(161):ra11.
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Pomegranate fruit extract impairs invasion and motility in human breast cancer. Integr Cancer Ther. 2009 Sep; 8(3):242-53.
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Deregulation of Tpl2 and NF-kappaB signaling and induction of macrophage apoptosis by the anti-depressant drug lithium. Cell Signal. 2009 Apr; 21(4):559-66.
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Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid. Arch Biochem Biophys. 2009 Jan 01; 481(1):123-30.
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Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell. 2007 Aug; 12(2):115-30.
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Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells. J Biol Chem. 2006 May 19; 281(20):14041-7.
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Phosphorylation of NF-kappaB1/p105 by oncoprotein kinase Tpl2: implications for a novel mechanism of Tpl2 regulation. Biochim Biophys Acta. 2006 Feb; 1763(2):174-81.