Transcription Factor RelB
"Transcription Factor RelB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that takes part in the NF-kappa-B complex by interacting with NF-KAPPA B P50 SUBUNIT or NF-KAPPA B P52 SUBUNIT. It regulates GENETIC TRANSCRIPTION that is involved in immune and inflammatory responses.
Descriptor ID |
D051841
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MeSH Number(s) |
D12.776.260.600.500 D12.776.660.600.500 D12.776.930.600.500
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Concept/Terms |
Transcription Factor RelB- Transcription Factor RelB
- RelB, Transcription Factor
- Rel-Related Protein
- Rel Related Protein
- v-Rel Reticuloendotheliosis Viral Oncogene Homolog B
- v Rel Reticuloendotheliosis Viral Oncogene Homolog B
- Inhibitory Rel Protein
- Rel Protein, Inhibitory
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor RelB".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor RelB".
This graph shows the total number of publications written about "Transcription Factor RelB" by people in this website by year, and whether "Transcription Factor RelB" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
1996 | 0 | 3 | 3 |
1997 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2009 | 1 | 1 | 2 |
2014 | 1 | 0 | 1 |
2015 | 2 | 0 | 2 |
2022 | 1 | 0 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor RelB" by people in Profiles.
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RelB-deficient autoinflammatory pathology presents as interferonopathy, but in mice is interferon-independent. J Allergy Clin Immunol. 2023 11; 152(5):1261-1272.
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NF?B pathway dysregulation due to reduced RelB expression leads to severe autoimmune disorders and declining immunity. J Autoimmun. 2023 May; 137:102946.
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Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth. Nat Commun. 2015 Oct 12; 6:8428.
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Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB. Toxicol Appl Pharmacol. 2015 Jul 15; 286(2):92-101.
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a-catenin acts as a tumour suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-?B signalling. Nat Cell Biol. 2014 Mar; 16(3):245-54.
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Inhibition of RelB by 1,25-dihydroxyvitamin D3 promotes sensitivity of breast cancer cells to radiation. J Cell Physiol. 2009 Sep; 220(3):593-9.
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Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. Mol Cell Biol. 2009 Apr; 29(7):1959-71.
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Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cells. Cancer. 2002 Oct 15; 95(8):1696-705.
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Calcium signaling inhibits interleukin-12 production and activates CD83(+) dendritic cells that induce Th2 cell development. Blood. 2001 Oct 15; 98(8):2489-97.
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The 18-wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense. EMBO J. 1997 Oct 15; 16(20):6120-30.