"Stem Cell Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hematopoietic growth factor and the ligand of the cell surface c-kit protein (PROTO-ONCOGENE PROTEINS C-KIT). It is expressed during embryogenesis and is a growth factor for a number of cell types including the MAST CELLS and the MELANOCYTES in addition to the HEMATOPOIETIC STEM CELLS.
| Descriptor ID |
D019089
|
| MeSH Number(s) |
D12.644.276.374.410.800 D12.776.467.374.410.800 D23.529.374.410.800
|
| Concept/Terms |
Stem Cell Factor- Stem Cell Factor
- Steel Factor
- Mast Cell Growth Factor
- c-kit Ligand
- c kit Ligand
- kit Ligand
|
Below are MeSH descriptors whose meaning is more general than "Stem Cell Factor".
Below are MeSH descriptors whose meaning is more specific than "Stem Cell Factor".
This graph shows the total number of publications written about "Stem Cell Factor" by people in this website by year, and whether "Stem Cell Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
To return to the timeline,
click here.
Below are the most recent publications written about "Stem Cell Factor" by people in Profiles.
-
Inhibition of Mast Cell-Derived Histamine Decreases Human Cholangiocarcinoma Growth and Differentiation via c-Kit/Stem Cell Factor-Dependent Signaling. Am J Pathol. 2016 Jan; 186(1):123-33.
-
Allelic Mutations of KITLG, Encoding KIT Ligand, Cause Asymmetric and Unilateral Hearing Loss and Waardenburg Syndrome Type 2. Am J Hum Genet. 2015 Nov 05; 97(5):647-60.
-
Regulation of FOXO3 subcellular localization by Kit ligand in the neonatal mouse ovary. J Assist Reprod Genet. 2015 Dec; 32(12):1741-7.
-
Circulating levels of endothelial progenitor cell mobilizing factors in the metabolic syndrome. Am J Cardiol. 2010 Dec 01; 106(11):1606-8.
-
Activin bioactivity affects germ cell differentiation in the postnatal mouse testis in vivo. Biol Reprod. 2010 May; 82(5):980-90.
-
Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases. Future Oncol. 2008 Oct; 4(5):611-21.
-
Utility of the World Heath Organization classification criteria for the diagnosis of systemic mastocytosis in bone marrow. Mod Pathol. 2009 Jan; 22(1):50-7.
-
Loss of the transmembrane but not the soluble kit ligand isoform increases testicular germ cell tumor susceptibility in mice. Cancer Res. 2008 Jul 01; 68(13):5193-7.
-
Increased expression of stem cell factor and its receptor after left ventricular assist device support: a potential novel target for therapeutic interventions in heart failure. J Heart Lung Transplant. 2008 Jul; 27(7):701-9.
-
Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib. Cancer. 2007 Mar 01; 109(5):907-14.