Macrophage Colony-Stimulating Factor
"Macrophage Colony-Stimulating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mononuclear phagocyte colony-stimulating factor (M-CSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF is a disulfide-bonded glycoprotein dimer with a MW of 70 kDa. It binds to a specific high affinity receptor (RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR).
| Descriptor ID |
D016173
|
| MeSH Number(s) |
D12.644.276.374.410.240.500 D12.776.395.240.500 D12.776.467.374.410.240.500 D23.529.374.410.240.500
|
| Concept/Terms |
Macrophage Colony-Stimulating Factor- Macrophage Colony-Stimulating Factor
- M-CSF
- CSF-1
- CSF-M
- Colony-Stimulating Factor 1
- Colony Stimulating Factor 1
- Colony-Stimulating Factor, Macrophage
- Colony Stimulating Factor, Macrophage
|
Below are MeSH descriptors whose meaning is more general than "Macrophage Colony-Stimulating Factor".
Below are MeSH descriptors whose meaning is more specific than "Macrophage Colony-Stimulating Factor".
This graph shows the total number of publications written about "Macrophage Colony-Stimulating Factor" by people in this website by year, and whether "Macrophage Colony-Stimulating Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Macrophage Colony-Stimulating Factor" by people in Profiles.
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MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma. JCI Insight. 2023 07 10; 8(13).
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Elevated expression of the colony-stimulating factor 1 (CSF1) induces prostatic intraepithelial neoplasia dependent of epithelial-Gp130. Oncogene. 2022 Feb; 41(9):1309-1323.
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The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice. Nat Commun. 2020 06 03; 11(1):2782.
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NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis. Cancer Res. 2014 Jul 01; 74(13):3477-88.
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Treatment of tenosynovial giant cell tumor and pigmented villonodular synovitis. Curr Opin Oncol. 2011 Jul; 23(4):361-6.
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Resumption of HIV replication is associated with monocyte/macrophage derived cytokine and chemokine changes: results from a large international clinical trial. AIDS. 2011 Jun 01; 25(9):1207-17.
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Combined use of biomarkers for detection of ovarian cancer in high-risk women. Tumour Biol. 2010 Jun; 31(3):209-15.
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Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):151-6.
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C-reactive protein induces M-CSF release and macrophage proliferation. J Leukoc Biol. 2009 Feb; 85(2):262-7.
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Role of microRNAs in drug-resistant ovarian cancer cells. Gynecol Oncol. 2008 Dec; 111(3):478-86.