"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
|
| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 1 | 3 |
| 1996 | 7 | 2 | 9 |
| 1997 | 4 | 3 | 7 |
| 1998 | 4 | 1 | 5 |
| 1999 | 1 | 3 | 4 |
| 2000 | 3 | 3 | 6 |
| 2001 | 4 | 9 | 13 |
| 2002 | 8 | 6 | 14 |
| 2003 | 14 | 12 | 26 |
| 2004 | 8 | 7 | 15 |
| 2005 | 11 | 14 | 25 |
| 2006 | 22 | 24 | 46 |
| 2007 | 13 | 31 | 44 |
| 2008 | 13 | 21 | 34 |
| 2009 | 16 | 33 | 49 |
| 2010 | 19 | 28 | 47 |
| 2011 | 23 | 26 | 49 |
| 2012 | 22 | 30 | 52 |
| 2013 | 27 | 37 | 64 |
| 2014 | 14 | 34 | 48 |
| 2015 | 13 | 21 | 34 |
| 2016 | 25 | 29 | 54 |
| 2017 | 18 | 25 | 43 |
| 2018 | 18 | 18 | 36 |
| 2019 | 17 | 22 | 39 |
| 2020 | 12 | 29 | 41 |
| 2021 | 13 | 19 | 32 |
| 2022 | 11 | 8 | 19 |
| 2023 | 8 | 6 | 14 |
| 2024 | 15 | 9 | 24 |
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Below are the most recent publications written about "Histones" by people in Profiles.
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Interplay of Reactive Oxygen Species (ROS) and Epigenetic Remodelling in Cardiovascular Diseases Pathogenesis: A Contemporary Perspective. Front Biosci (Landmark Ed). 2024 Nov 21; 29(11):398.
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Nuclear PD-L1 compartmentalization suppresses tumorigenesis and overcomes immunocheckpoint therapy resistance in mice via histone macroH2A1. J Clin Invest. 2024 Nov 15; 134(22).
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Epigenome Reprogramming Through H3K27 and H3K4 Trimethylation as a Resistance Mechanism to DNA Methylation Inhibition in BRAFV600E-Mutated Colorectal Cancer. Clin Cancer Res. 2024 Nov 15; 30(22):5166-5179.
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Histone lactylation drives CD8+ T cell metabolism and function. Nat Immunol. 2024 Nov; 25(11):2140-2151.
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USF2 and TFEB compete in regulating lysosomal and autophagy genes. Nat Commun. 2024 Sep 27; 15(1):8334.
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Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification. Elife. 2024 Aug 19; 13.
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Histone serotonylation regulates ependymoma tumorigenesis. Nature. 2024 Aug; 632(8026):903-910.
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SMYD5 is a regulator of the mild hypothermia response. Cell Rep. 2024 Aug 27; 43(8):114554.
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TRPS1 expression in MPNST is correlated with PRC2 inactivation and loss of H3K27me3. Hum Pathol. 2024 09; 151:105632.
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Ubiquitin-induced RNF168 condensation promotes DNA double-strand break repair. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2322972121.