"Histones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small chromosomal proteins (approx 12-20 kD) possessing an open, unfolded structure and attached to the DNA in cell nuclei by ionic linkages. Classification into the various types (designated histone I, histone II, etc.) is based on the relative amounts of arginine and lysine in each.
| Descriptor ID |
D006657
|
| MeSH Number(s) |
D12.776.157.687.485 D12.776.660.720.485 D12.776.664.469
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histones".
Below are MeSH descriptors whose meaning is more specific than "Histones".
This graph shows the total number of publications written about "Histones" by people in this website by year, and whether "Histones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 3 | 4 |
| 2003 | 4 | 4 | 8 |
| 2004 | 2 | 1 | 3 |
| 2005 | 2 | 3 | 5 |
| 2006 | 4 | 5 | 9 |
| 2007 | 1 | 2 | 3 |
| 2008 | 4 | 4 | 8 |
| 2009 | 6 | 10 | 16 |
| 2010 | 4 | 9 | 13 |
| 2011 | 7 | 8 | 15 |
| 2012 | 7 | 10 | 17 |
| 2013 | 7 | 14 | 21 |
| 2014 | 7 | 16 | 23 |
| 2015 | 8 | 19 | 27 |
| 2016 | 9 | 15 | 24 |
| 2017 | 5 | 16 | 21 |
| 2018 | 10 | 6 | 16 |
| 2019 | 8 | 15 | 23 |
| 2020 | 6 | 14 | 20 |
| 2021 | 7 | 13 | 20 |
| 2022 | 7 | 4 | 11 |
| 2023 | 8 | 6 | 14 |
| 2024 | 11 | 3 | 14 |
| 2025 | 8 | 9 | 17 |
| 2026 | 1 | 4 | 5 |
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click here.
Below are the most recent publications written about "Histones" by people in Profiles.
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Hp1bp3 loss links chromatin reorganization to metabolic vulnerability in glioma. Proc Natl Acad Sci U S A. 2026 Jun 16; 123(24):e2601061123.
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H3K27me3 spreading organizes canonical PRC1 chromatin architecture to regulate developmental programs. Nat Genet. 2026 Jun; 58(6):1368-1382.
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Cigarette smoke induces FASN-dependent fatty acid metabolic rewiring to drive bladder cancer progression. Cancer Lett. 2026 Aug 10; 653:218562.
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CHK1 is an integral regulator of DNA replication in human cells. Cell Death Dis. 2026 Mar 26; 17(1).
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A side-by-side comparison of commercial CUT&RUN kits. J Biomol Tech. 2026; 37(1):4-17.
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Rare epigenetic alterations are conserved across hematopoietic differentiation stages after mycobacterial infection. JCI Insight. 2026 Jan 23; 11(2).
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Bromodomain-Driven Regulation of Stem Cells: A Potential Target for Cancer Therapeutic Intervention. Stem Cell Rev Rep. 2026 02; 22(2):767-802.
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EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism. Acta Neuropathol Commun. 2025 11 07; 13(1):227.
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ADNP Exhibits Methyltransferase Activity in Overexpression Systems and Modulates DNA and Histone Methylation. Autism Res. 2025 Nov; 18(11):2174-2191.
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A needed nomenclature for nucleosomes. Mol Cell. 2025 Oct 02; 85(19):3554-3561.