Receptors, Cytoplasmic and Nuclear

"Receptors, Cytoplasmic and Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

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Intracellular receptors that can be found in the cytoplasm or in the nucleus. They bind to extracellular signaling molecules that migrate through or are transported across the CELL MEMBRANE. Many members of this class of receptors occur in the cytoplasm and are transported to the CELL NUCLEUS upon ligand-binding where they signal via DNA-binding and transcription regulation. Also included in this category are receptors found on INTRACELLULAR MEMBRANES that act via mechanisms similar to CELL SURFACE RECEPTORS.

Descriptor ID	D018160
MeSH Number(s)	D12.776.826
Concept/Terms	Receptors, Cytoplasmic and Nuclear Receptors, Cytoplasmic and Nuclear Receptors, Cytosol and Nuclear Cytosolic and Nuclear Receptors Receptors, Nuclear and Cytoplasmic Cytoplasmic and Nuclear Receptors Cytosol and Nuclear Receptors Nuclear and Cytoplasmic Receptors Receptors, Cytosolic and Nuclear Receptors, Nuclear Receptors, Nuclear Nuclear Receptors Receptors, Cytoplasmic Receptors, Cytoplasmic Cytoplasmic Receptors Receptors, Intracellular Membrane Receptors, Intracellular Membrane Membrane Receptors, Intracellular Intracellular Membrane Receptors Hormone Receptors, Cytoplasmic Hormone Receptors, Cytoplasmic Receptors, Cytoplasmic Hormone Cytoplasmic Hormone Receptors Hormone Receptors, Nuclear Hormone Receptors, Nuclear Receptors, Nuclear Hormone Nuclear Hormone Receptors

Below are MeSH descriptors whose meaning is more general than "Receptors, Cytoplasmic and Nuclear".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Receptors, Cytoplasmic and Nuclear [D12.776.826]

Below are MeSH descriptors whose meaning is related to "Receptors, Cytoplasmic and Nuclear".

Below are MeSH descriptors whose meaning is more specific than "Receptors, Cytoplasmic and Nuclear".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Receptors, Cytoplasmic and Nuclear" by people in this website by year, and whether "Receptors, Cytoplasmic and Nuclear" was a major or minor topic of these publications.

Bar chart showing 391 publications over 31 distinct years, with a maximum of 39 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	1	1
1993	2	0	2
1994	3	0	3
1995	1	0	1
1996	1	2	3
1997	8	2	10
1998	4	2	6
1999	7	7	14
2000	7	7	14
2001	15	6	21
2002	13	6	19
2003	22	9	31
2004	14	16	30
2005	27	12	39
2006	14	7	21
2007	15	2	17
2008	7	2	9
2009	10	4	14
2010	10	7	17
2011	10	5	15
2012	11	1	12
2013	10	4	14
2014	9	5	14
2015	11	2	13
2016	8	3	11
2017	9	2	11
2018	5	3	8
2019	5	2	7
2020	5	2	7
2021	4	1	5
2022	1	1	2

Below are the most recent publications written about "Receptors, Cytoplasmic and Nuclear" by people in Profiles.

Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, Fuentes-Prior P, MacKenzie KR, Benn CL, Estébanez-Perpiñá E, Venken K, Moore DD, Young DW, Maletic-Savatic M. Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022 03 29; 119(13):e2023784119.

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Krivdova G, Voisin V, Schoof EM, Marhon SA, Murison A, McLeod JL, Gabra MM, Zeng AGX, Aigner S, Yee BA, Shishkin AA, Van Nostrand EL, Hermans KG, Trotman-Grant AC, Mbong N, Kennedy JA, Gan OI, Wagenblast E, De Carvalho DD, Salmena L, Minden MD, Bader GD, Yeo GW, Dick JE, Lechman ER. Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML. Cell Rep. 2022 03 08; 38(10):110481.

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Vonderohe C, Guthrie G, Stoll B, Chacko S, Dawson H, Burrin DG. Tissue-specific mechanisms of bile acid homeostasis and activation of FXR-FGF19 signaling in preterm and term neonatal pigs. Am J Physiol Gastrointest Liver Physiol. 2022 01 01; 322(1):G117-G133.

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So SY, Wu Q, Leung KS, Kundi ZM, Savidge TC, El-Nezami H. Yeast ß-glucan reduces obesity-associated Bilophila abundance and modulates bile acid metabolism in healthy and high-fat diet mouse models. Am J Physiol Gastrointest Liver Physiol. 2021 12 01; 321(6):G639-G655.

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Thein KZ, Piha-Paul SA, Tsimberidou A, Karp DD, Janku F, Zarifa A, Shah J, Milton DR, Bean S, McQuinn L, Gong J, Colen R, Carter BW, Subbiah V, Ogbonna DC, Pant S, Meric-Bernstam F, Naing A. Selinexor in combination with topotecan in patients with advanced or metastatic solid tumors: Results of an open-label, single-center, multi-arm phase Ib study. Invest New Drugs. 2021 10; 39(5):1357-1365.

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Chen ML, Huang X, Wang H, Hegner C, Liu Y, Shang J, Eliason A, Diao H, Park H, Frey B, Wang G, Mosure SA, Solt LA, Kojetin DJ, Rodriguez-Palacios A, Schady DA, Weaver CT, Pipkin ME, Moore DD, Sundrud MS. CAR directs T cell adaptation to bile acids in the small intestine. Nature. 2021 05; 593(7857):147-151.

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Inoue A, Robinson FS, Minelli R, Tomihara H, Rizi BS, Rose JL, Kodama T, Srinivasan S, Harris AL, Zuniga AM, Mullinax RA, Ma X, Seth S, Daniele JR, Peoples MD, Loponte S, Akdemir KC, Khor TO, Feng N, Roszik J, Sobieski MM, Brunell D, Stephan C, Giuliani V, Deem AK, Shingu T, Deribe YL, Menter DG, Heffernan TP, Viale A, Bristow CA, Kopetz S, Draetta GF, Genovese G, Carugo A. Sequential Administration of XPO1 and ATR Inhibitors Enhances Therapeutic Response in TP53-mutated Colorectal Cancer. Gastroenterology. 2021 07; 161(1):196-210.

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Deng M, Zhang M, Xu-Monette ZY, Pham LV, Tzankov A, Visco C, Fang X, Bhagat G, Zhu F, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Choi WWL, Huh J, Ponzoni M, Ferreri AJM, Møller MB, Parsons BM, van Krieken JH, Piris MA, Winter JN, Hagemeister F, Alinari L, Li Y, Andreeff M, Xu B, Young KH. XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53. J Hematol Oncol. 2020 11 04; 13(1):148.

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Guan D, Xiong Y, Trinh TM, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz JD, Lazar MA. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020 09 11; 369(6509):1388-1394.

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Marques-Piubelli ML, Tetzlaff MT, Nagarajan P, Duke TC, Glitza Oliva IC, Ledesma DA, Aung PP, Torres-Cabala CA, Wistuba II, Prieto VG, Nelson KC, Curry JL. Hypertrophic lichenoid dermatitis immune-related adverse event during combined immune checkpoint and exportin inhibitor therapy: A diagnostic pitfall for superficially invasive squamous cell carcinoma. J Cutan Pathol. 2020 Oct; 47(10):954-959.

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