"Complement Factor B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycine-rich, heat-labile serum glycoprotein that contains a component of the C3 CONVERTASE ALTERNATE PATHWAY (C3bBb). Bb, a serine protease, is generated when factor B is cleaved by COMPLEMENT FACTOR D into Ba and Bb.
Descriptor ID |
D011415
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MeSH Number(s) |
D08.622.200 D08.811.277.656.300.760.198 D08.811.277.656.959.350.198 D12.776.124.486.274.900
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Concept/Terms |
Complement Factor B- Complement Factor B
- Factor B, Complement
- C3 Proactivator
- Proactivator, C3
- C3PA
- Complement 3 Proactivator
- Proactivator, Complement 3
- Factor B
- Complement Protein B
- Protein B, Complement
- Complement Protein Factor B
- Properdin Factor B
- Factor B, Properdin
- Complement Factor B, Alternative Pathway
Complement Factor Bb- Complement Factor Bb
- Bb, Complement Factor
- Factor Bb, Complement
- Properdin Factor Bb
- Factor Bb, Properdin
- Complement Factor B-Derived Fragment Bb
- Complement Factor B Derived Fragment Bb
- Bb Fragment of Factor B
- Complement Factor B Fragment, Bb
Complement Factor Ba- Complement Factor Ba
- Factor Ba, Complement
- Properdin Factor Ba
- Factor Ba, Properdin
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Below are MeSH descriptors whose meaning is more general than "Complement Factor B".
Below are MeSH descriptors whose meaning is more specific than "Complement Factor B".
This graph shows the total number of publications written about "Complement Factor B" by people in this website by year, and whether "Complement Factor B" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Complement Factor B" by people in Profiles.
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Heat-inactivated Factor B inhibits alternative pathway fluid-phase activation and convertase formation on endothelial cell-secreted ultra-large von Willebrand factor strings. Sci Rep. 2023 04 08; 13(1):5764.
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Urine Complement Factor Ba Is Associated with AKI in Critically Ill Children. Kidney360. 2023 03 01; 4(3):326-332.
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The alternative complement pathway activation product Ba as a marker for transplant-associated thrombotic microangiopathy. Pediatr Blood Cancer. 2020 03; 67(3):e28070.
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Complement Split Products in Amniotic Fluid in Pregnancies Subsequently Developing Early-Onset Preeclampsia. Dis Markers. 2015; 2015:263109.
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Mammalian DNA is an endogenous danger signal that stimulates local synthesis and release of complement factor B. Mol Med. 2012 Jul 18; 18:851-60.
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Surviving mousepox infection requires the complement system. PLoS Pathog. 2008 Dec; 4(12):e1000249.
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Sepsis score and acute-phase protein response as predictors of outcome in septic surgical patients. Arch Surg. 1987 Feb; 122(2):141-6.
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Sepsis score and complement factor B for monitoring severely septic surgical patients and for predicting their survival. Eur Surg Res. 1985; 17(5):269-80.
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Genetic marker for insulin-dependent diabetes mellitus. Lancet. 1979 Jun 09; 1(8128):1208-10.