"Complement C9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
| Descriptor ID |
D003186
|
| MeSH Number(s) |
D12.776.124.486.274.850
|
| Concept/Terms |
Complement C9- Complement C9
- C9, Complement
- Complement 9
- Complement Component 9
- Component 9, Complement
- C9 Complement
- Complement, C9
|
Below are MeSH descriptors whose meaning is more general than "Complement C9".
Below are MeSH descriptors whose meaning is more specific than "Complement C9".
This graph shows the total number of publications written about "Complement C9" by people in this website by year, and whether "Complement C9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement C9" by people in Profiles.
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Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement Activation. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004310.
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Expression of complement components coincides with early patterning and organogenesis in Xenopus laevis. Int J Dev Biol. 2008; 52(8):1123-33.
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Supplemental complement component C9 enhances the capacity of neonatal serum to kill multiple isolates of pathogenic Escherichia coli. Pediatr Res. 1994 Apr; 35(4 Pt 1):389-96.
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Differences in cell-bound C8 sites on chicken erythrocytes measured by their reactivity with guinea pig and human C9. J Immunol. 1980 Dec; 125(6):2818-22.
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Distinction between C8-mediated and C8/C9-mediated hemolysis on the basis of independent 86Rb and hemoglobin release. J Immunol. 1980 Apr; 124(4):1905-10.