"Complement C4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein that is important in the activation of CLASSICAL COMPLEMENT PATHWAY. C4 is cleaved by the activated COMPLEMENT C1S into COMPLEMENT C4A and COMPLEMENT C4B.
| Descriptor ID |
D003181
|
| MeSH Number(s) |
D12.776.124.486.274.350
|
| Concept/Terms |
Complement C4- Complement C4
- C4, Complement
- Complement Component 4
- Component 4, Complement
- Complement 4
- C4 Complement
- Complement, C4
- C4 Complement Component
- Complement Component, C4
- Component, C4 Complement
|
Below are MeSH descriptors whose meaning is more general than "Complement C4".
Below are MeSH descriptors whose meaning is more specific than "Complement C4".
This graph shows the total number of publications written about "Complement C4" by people in this website by year, and whether "Complement C4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement C4" by people in Profiles.
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Development of clinical and laboratory biomarkers in an international cohort of 428 children with lupus nephritis. Pediatr Nephrol. 2024 Oct; 39(10):2959-2968.
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Elevated oxidized lipids, anti-lipid autoantibodies and oxidized lipid immune complexes in active SLE. Clin Immunol. 2019 08; 205:43-48.
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Schizophrenia: From genetics to physiology at last. Nature. 2016 Feb 11; 530(7589):162-3.
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Surviving mousepox infection requires the complement system. PLoS Pathog. 2008 Dec; 4(12):e1000249.
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Analysis of C4 and the C4 binding protein in the MRL/lpr mouse. Arthritis Res Ther. 2007; 9(5):R114.
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Regulation of the B cell response to T-dependent antigens by classical pathway complement. J Immunol. 1996 Jul 15; 157(2):549-56.
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Phase I clinical and pharmacological study of suppression of human antimouse antibody response to monoclonal antibody L6 by deoxyspergualin. Cancer Res. 1995 Jul 15; 55(14):3060-7.
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Connective tissue disease in southeast Georgia. A community based study of immunogenetic markers and autoantibodies. J Rheumatol. 1990 Aug; 17(8):1029-35.
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C4A gene deletion and HLA associations in black Americans with systemic lupus erythematosus. Immunogenetics. 1989; 30(1):27-33.
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Molecular heterogeneity of complement component C4-null and 21-hydroxylase genes in systemic lupus erythematosus. Arthritis Rheum. 1988 Jun; 31(6):736-44.