"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.
| Descriptor ID |
D016207
|
| MeSH Number(s) |
D12.644.276.374 D12.776.467.374 D23.529.374
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cytokines".
Below are MeSH descriptors whose meaning is more specific than "Cytokines".
This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 3 | 8 |
| 1996 | 6 | 1 | 7 |
| 1997 | 3 | 0 | 3 |
| 1998 | 9 | 5 | 14 |
| 1999 | 11 | 8 | 19 |
| 2000 | 5 | 6 | 11 |
| 2001 | 8 | 11 | 19 |
| 2002 | 6 | 13 | 19 |
| 2003 | 7 | 11 | 18 |
| 2004 | 7 | 25 | 32 |
| 2005 | 11 | 16 | 27 |
| 2006 | 11 | 20 | 31 |
| 2007 | 12 | 22 | 34 |
| 2008 | 14 | 18 | 32 |
| 2009 | 15 | 26 | 41 |
| 2010 | 6 | 19 | 25 |
| 2011 | 15 | 31 | 46 |
| 2012 | 8 | 19 | 27 |
| 2013 | 13 | 26 | 39 |
| 2014 | 11 | 29 | 40 |
| 2015 | 11 | 24 | 35 |
| 2016 | 6 | 42 | 48 |
| 2017 | 7 | 36 | 43 |
| 2018 | 11 | 21 | 32 |
| 2019 | 7 | 26 | 33 |
| 2020 | 11 | 25 | 36 |
| 2021 | 7 | 30 | 37 |
| 2022 | 3 | 40 | 43 |
| 2023 | 3 | 34 | 37 |
| 2024 | 1 | 13 | 14 |
| 2025 | 6 | 4 | 10 |
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Below are the most recent publications written about "Cytokines" by people in Profiles.
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Exogenous arginine differentially regulates inflammatory cytokine and inducible nitric oxide synthase expression in macrophages. Immunohorizons. 2025 Jul 14; 9(8).
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Temporal Regulation of Early-Stage Cytokine Expression in Diabetic Wound Healing Under Negative Pressure Wound Therapy. Int J Mol Sci. 2025 May 13; 26(10).
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Identification of Distinct Biological Groups of Patients With Cryptogenic NORSE via Inflammatory Profiling. Neurol Neuroimmunol Neuroinflamm. 2025 Jul; 12(4):e200403.
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Impact of High-Titer Convalescent Plasma on Clinical and Virologic Outcomes Among Veterans Hospitalized With SARS-CoV-2 Infection: VA CoronavirUs Research and Efficacy Studies-1 (VA CURES-1). J Med Virol. 2025 May; 97(5):e70349.
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Dessicating stress triggers and exacerbates experimental ocular Graft-versus-host-disease. Ocul Surf. 2025 Jul; 37:236-246.
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Amniotic fluid-derived mesenchymal stem cells as a therapeutic tool against cytokine storm: a comparison with umbilical cord counterparts. Stem Cell Res Ther. 2025 Mar 28; 16(1):151.
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Early cytokine signatures and clinical phenotypes discriminate persistent from resolving MRSA bacteremia. BMC Infect Dis. 2025 Feb 18; 25(1):231.
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Comprehensive normalization and binary classification methods for enhanced sensitivity and reproducibility in Luminex assay quantitation. J Immunol Methods. 2025 Mar; 538:113826.
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Immune profiling of human vestibular schwannoma secretions identifies TNF-a and TWEAK as cytokines with synergistic potential to impair hearing. J Neuroinflammation. 2025 Feb 08; 22(1):35.
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens. mBio. 2025 Feb 05; 16(2):e0341224.