"Lactoferrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.
Descriptor ID |
D007781
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MeSH Number(s) |
D08.811.277.656.300.760.471 D08.811.277.656.959.350.471 D12.776.157.427.750.249 D12.776.256.626.816.500.507 D12.776.377.457.507 D12.776.395.507 D12.776.556.579.750.249
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lactoferrin".
Below are MeSH descriptors whose meaning is more specific than "Lactoferrin".
This graph shows the total number of publications written about "Lactoferrin" by people in this website by year, and whether "Lactoferrin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 1 | 2 |
1996 | 4 | 1 | 5 |
1997 | 2 | 2 | 4 |
1998 | 2 | 1 | 3 |
1999 | 3 | 0 | 3 |
2000 | 2 | 1 | 3 |
2001 | 1 | 1 | 2 |
2002 | 1 | 0 | 1 |
2003 | 2 | 0 | 2 |
2004 | 1 | 0 | 1 |
2005 | 1 | 1 | 2 |
2006 | 3 | 0 | 3 |
2007 | 4 | 1 | 5 |
2008 | 2 | 0 | 2 |
2009 | 1 | 0 | 1 |
2011 | 3 | 0 | 3 |
2013 | 2 | 0 | 2 |
2015 | 2 | 1 | 3 |
2017 | 2 | 0 | 2 |
2018 | 1 | 0 | 1 |
2019 | 2 | 0 | 2 |
2020 | 3 | 1 | 4 |
2021 | 0 | 1 | 1 |
2022 | 1 | 0 | 1 |
2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lactoferrin" by people in Profiles.
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Probiotics, Prebiotics, and Lactoferrin-Implications for Preterm Mortality and Morbidity. JAMA Pediatr. 2023 11 01; 177(11):1129-1131.
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Resistin, Elastase, and Lactoferrin as Potential Plasma Biomarkers of Pediatric Inflammatory Bowel Disease Based on Comprehensive Proteomic Screens. Mol Cell Proteomics. 2023 02; 22(2):100487.
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BMP/SMAD1/5 Signaling in the Endometrial Epithelium Is Essential for Receptivity and Early Pregnancy. Endocrinology. 2022 05 01; 163(5).
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Lactoferrin amyloid presenting as a mural nodule in a pancreatic cystic lesion prompting pancreatoduodenectomy: a case report. BMC Gastroenterol. 2021 Feb 12; 21(1):66.
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Evidence from systematic reviews of randomized trials on enteral lactoferrin supplementation in preterm neonates. Biochem Cell Biol. 2021 02; 99(1):20-24.
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ITLN1 modulates invasive potential and metabolic reprogramming of ovarian cancer cells in omental microenvironment. Nat Commun. 2020 07 15; 11(1):3546.
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The effect of lactoferrin supplementation on death or major morbidity in very low birthweight infants (LIFT): a multicentre, double-blind, randomised controlled trial. Lancet Child Adolesc Health. 2020 06; 4(6):444-454.
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Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants. Cochrane Database Syst Rev. 2020 03 31; 3:CD007137.
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Enteral lactoferrin for the treatment of sepsis and necrotizing enterocolitis in neonates. Cochrane Database Syst Rev. 2019 05 11; 5:CD007138.
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Supplementation With Lactoferrin and Lysozyme Ameliorates Environmental Enteric Dysfunction: A Double-Blind, Randomized, Placebo-Controlled Trial. Am J Gastroenterol. 2019 04; 114(4):671-678.