Item Type | Name |
Academic Article
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Experience with heat shock protein-peptide complex 96 vaccine therapy in patients with indolent non-Hodgkin lymphoma.
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Academic Article
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Plasmablastic lymphomas and plasmablastic plasma cell myelomas have nearly identical immunophenotypic profiles.
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Academic Article
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High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei.
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Academic Article
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The histone deacetylase inhibitor entinostat (SNDX-275) induces apoptosis in?Hodgkin lymphoma cells and synergizes with Bcl-2 family inhibitors.
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Concept
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Homeodomain Proteins
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Concept
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Multidrug Resistance-Associated Proteins
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Concept
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Suppressor of Cytokine Signaling Proteins
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Concept
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Ribosomal Proteins
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Concept
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Oncogene Proteins, Viral
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Concept
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Adaptor Proteins, Signal Transducing
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Concept
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Proto-Oncogene Proteins c-myc
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Concept
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Membrane Proteins
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Concept
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DNA-Binding Proteins
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Concept
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Oncogene Proteins, Fusion
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Concept
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Heat-Shock Proteins
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Concept
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Proto-Oncogene Proteins c-pim-1
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Concept
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Nuclear Pore Complex Proteins
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Concept
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Proto-Oncogene Proteins B-raf
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Concept
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Luminescent Proteins
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Concept
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Chromosomal Proteins, Non-Histone
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Concept
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Carrier Proteins
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Concept
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Proto-Oncogene Proteins c-bcl-2
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Concept
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Oncogene Proteins
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Concept
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Cell Cycle Proteins
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Concept
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Mitochondrial Proteins
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Concept
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Retinoblastoma Binding Proteins
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Concept
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Green Fluorescent Proteins
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Concept
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ras Proteins
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Concept
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Recombinant Fusion Proteins
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Concept
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Inhibitor of Apoptosis Proteins
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Concept
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Proto-Oncogene Proteins c-bcr
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Concept
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Intermediate Filament Proteins
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Concept
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Hedgehog Proteins
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Concept
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Nuclear Proteins
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Concept
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Proto-Oncogene Proteins c-jun
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Concept
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Neoplasm Proteins
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Concept
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Proto-Oncogene Proteins p21(ras)
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Concept
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Pore Forming Cytotoxic Proteins
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Concept
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I-kappa B Proteins
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Concept
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Proto-Oncogene Proteins c-ret
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Concept
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Viral Matrix Proteins
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Concept
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Proto-Oncogene Proteins c-fos
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Concept
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Fusion Proteins, bcr-abl
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Concept
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Acute-Phase Proteins
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Concept
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S100 Proteins
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Concept
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Intracellular Signaling Peptides and Proteins
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Concept
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WT1 Proteins
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Concept
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Proto-Oncogene Proteins c-mdm2
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Concept
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Proto-Oncogene Proteins c-met
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Concept
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Apoptosis Regulatory Proteins
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Concept
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Telomere-Binding Proteins
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Concept
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Proto-Oncogene Proteins
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Concept
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Proto-Oncogene Proteins c-abl
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Concept
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Proto-Oncogene Proteins c-ets
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Concept
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Nerve Tissue Proteins
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Concept
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Tumor Suppressor Proteins
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Concept
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RNA-Binding Proteins
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Concept
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Viral Proteins
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Concept
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Intercellular Signaling Peptides and Proteins
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Concept
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Repressor Proteins
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Concept
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HSP90 Heat-Shock Proteins
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Concept
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Proto-Oncogene Proteins c-kit
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Concept
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Proto-Oncogene Proteins c-akt
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Concept
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Poly(A)-Binding Proteins
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Concept
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Proteins
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Concept
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Proto-Oncogene Proteins c-bcl-6
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Concept
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Microtubule-Associated Proteins
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Academic Article
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TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow.
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Academic Article
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Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease: clinical significance and comparison of chomosomal abnormalities in SM and AHNMD components.
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Academic Article
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Immunophenotypic heterogeneity of normal plasma cells: comparison with minimal residual plasma cell myeloma.
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Academic Article
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BRAF kinase domain mutations are present in a subset of chronic myelomonocytic leukemia with wild-type RAS.
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Academic Article
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Differential expression and clinical significance of tyrosine-phosphorylated STAT3 in ALK+ and ALK- anaplastic large cell lymphoma.
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Academic Article
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Activation status of the JAK/STAT3 pathway in mantle cell lymphoma.
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Academic Article
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Association of bcl-1 rearrangements with lymphocytic lymphoma of intermediate differentiation.
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Academic Article
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Appraisal of intratumoral microvessel density, MIB-1 score, DNA content, and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma.
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Academic Article
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Pagetoid bowen disease: a report of 2 cases that express cytokeratin 7.
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Academic Article
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Sinus histiocytosis with massive lymphadenopathy and malignant lymphoma involving the same lymph node: a report of four cases and review of the literature.
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Academic Article
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Prognostic implications of calbindin-D28k expression in lung cancer: analysis of 452 cases.
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Academic Article
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Cyclin D1 and E2F-1 immunoreactivity in bone marrow biopsy specimens of multiple myeloma: relationship to proliferative activity, cytogenetic abnormalities and DNA ploidy.
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Academic Article
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Differential expression of BCL-2 family proteins in ALK-positive and ALK-negative anaplastic large cell lymphoma of T/null-cell lineage.
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Academic Article
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Clusterin expression in malignant lymphomas: a survey of 266 cases.
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Academic Article
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TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin.
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Academic Article
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BCL-2 family proteins in peripheral T-cell lymphomas: correlation with tumour apoptosis and proliferation.
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Academic Article
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Expression of Epstein-Barr virus latent membrane protein-1 in Hodgkin and Reed-Sternberg cells of classical Hodgkin's lymphoma: associations with presenting features, serum interleukin 10 levels, and clinical outcome.
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Academic Article
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Signal transducer and activator of transcription-3 activation contributes to high tissue inhibitor of metalloproteinase-1 expression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
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Academic Article
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Differential expression of WT1 gene product in non-Hodgkin lymphomas.
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Academic Article
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JunB expression is a common feature of CD30+ lymphomas and lymphomatoid papulosis.
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Academic Article
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Hodgkin lymphoma involving Waldeyer ring: a clinicopathologic study of 22 cases.
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Academic Article
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Expression of heat-shock protein-90 in non-Hodgkin's lymphomas.
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Academic Article
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Lymphoid neoplasms associated with concurrent t(14;18) and 8q24/c-MYC translocation generally have a poor prognosis.
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Academic Article
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c-FLIP confers resistance to FAS-mediated apoptosis in anaplastic large-cell lymphoma.
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Academic Article
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Acute myeloid leukemia associated with variant t(8;21) detected by conventional cytogenetic and molecular studies: a report of four cases and review of the literature.
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Academic Article
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Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
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Academic Article
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Prognostic significance of Bcl-6 protein expression in DLBCL treated with CHOP or R-CHOP: a prospective correlative study.
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Academic Article
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Expression of Bcl-2 in gastrointestinal stromal tumors: correlation with progression-free survival in 81 patients treated with imatinib mesylate.
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Academic Article
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Intrinsic apoptotic pathway in anaplastic large cell lymphoma.
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Academic Article
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Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
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Academic Article
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MALT1 gene rearrangements and NF-kappaB activation involving p65 and p50 are absent or rare in primary MALT lymphomas of the breast.
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Academic Article
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The HSP90 inhibitor 17-AAG synergizes with doxorubicin and U0126 in anaplastic large cell lymphoma irrespective of ALK expression.
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Academic Article
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c-Jun expression and activation are restricted to CD30+ lymphoproliferative disorders.
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Academic Article
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Metastasis-associated protein 1 transgenic mice: a new model of spontaneous B-cell lymphomas.
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Academic Article
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Therapy-related acute myeloid leukemia with t(8;21) (q22;q22) shares many features with de novo acute myeloid leukemia with t(8;21)(q22;q22) but does not have a favorable outcome.
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Academic Article
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Chronic lymphocytic leukemia With t(2;14)(p16;q32) involves the BCL11A and IgH genes and is associated with atypical morphologic features and unmutated IgVH genes.
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Academic Article
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Angioimmunoblastic T-cell lymphoma in bone marrow: a morphologic and immunophenotypic study.
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Academic Article
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Trisomy 11 in myelodysplastic syndromes defines a unique group of disease with aggressive clinicopathologic features.
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Academic Article
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Immunohistochemical profile and fluorescence in situ hybridization analysis of diffuse large B-cell lymphoma in northern China.
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Academic Article
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Differential expression of CKS-1B in typical and blastoid variants of mantle cell lymphoma.
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Academic Article
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FLT3 and NPM1 mutations in myelodysplastic syndromes: Frequency and potential value for predicting progression to acute myeloid leukemia.
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Academic Article
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Chromosome 20q deletion: a recurrent cytogenetic abnormality in patients with chronic myelogenous leukemia in remission.
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Academic Article
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Activation of the p53 pathway by the MDM2 inhibitor nutlin-3a overcomes BCL2 overexpression in a preclinical model of diffuse large B-cell lymphoma associated with t(14;18)(q32;q21).
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Academic Article
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Trisomy 11 as an isolated abnormality in acute myeloid leukemia is associated with unfavorable prognosis but not with an NPM1 or KIT mutation.
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Academic Article
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CD117 expression is a sensitive but nonspecific predictor of FLT3 mutation in T acute lymphoblastic leukemia and T/myeloid acute leukemia.
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Academic Article
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Genotypic analysis of diffuse, mixed cell lymphomas. Comparison with morphologic and immunophenotypic findings.
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Academic Article
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Follicular center cell lymphoma with the t(14;18) translocation in which the rearranged BCL-2 gene is silent.
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Academic Article
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bcl-2 expression in Hodgkin's disease. Correlation with the t(14;18) translocation and Epstein-Barr virus.
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Academic Article
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Cystic dysplasia of the testis.
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Academic Article
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Subcutaneous panniculitic T-cell lymphoma is a tumor of cytotoxic T lymphocytes.
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Academic Article
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Hodgkin's disease in Costa Rica: a report of 40 cases analyzed for Epstein-Barr virus.
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Academic Article
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Expression of the cell-cycle-related proteins E2F-1, p53, mdm-2, p21waf-1, and Ki-67 in multiple myeloma: correlation with cyclin-D1 immunoreactivity.
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Academic Article
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Cyclin D1 overexpression in Spitz nevi: an immunohistochemical study.
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Academic Article
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Follicle center lymphoma and Warthin tumor involving the same anatomic site. Report of two cases and review of the literature.
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Academic Article
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Natural killer-cell lymphoma involving the gynecologic tract.
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Academic Article
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Pleural posttransplantation lymphoproliferative disorder following liver transplantation.
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Academic Article
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Primary follicular large cell lymphoma of the testis in a child.
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Academic Article
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DNA topoisomerase IIalpha in multiple myeloma: a marker of cell proliferation and not drug resistance.
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Academic Article
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Ovarian non-Hodgkin's lymphoma: a clinicopathologic study of eight primary cases.
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Academic Article
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Marginal-zone B-cell lymphoma of extranodal mucosa-associated lymphoid tissue type: molecular genetics provides new insights into pathogenesis.
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Academic Article
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BAX expression in Hodgkin and Reed-Sternberg cells of Hodgkin's disease: correlation with clinical outcome.
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Academic Article
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Real-Time t(14;18)(q32;q21) PCR assay combined with high-resolution capillary electrophoresis: a novel and rapid approach that allows accurate quantitation and size determination of bcl-2/JH fusion sequences.
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Academic Article
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Overexpression of Mcl-1 in anaplastic large cell lymphoma cell lines and tumors.
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Academic Article
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Establishment and characterization of a new mantle cell lymphoma cell line, Mino.
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Academic Article
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BCL-2 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin disease predicts a poorer prognosis in patients treated with ABVD or equivalent regimens.
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Academic Article
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Expression of STAT3 and its phosphorylated forms in mantle cell lymphoma cell lines and tumours.
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Academic Article
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Expression of Mcl-1 in mantle cell lymphoma is associated with high-grade morphology, a high proliferative state, and p53 overexpression.
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Academic Article
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Caspase-3 activation in systemic anaplastic large-cell lymphoma.
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Academic Article
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Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.
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Academic Article
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Isothermal multiple displacement amplification: a highly reliable approach for generating unlimited high molecular weight genomic DNA from clinical specimens.
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Academic Article
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Acute myeloid leukemia with t(6;9)(p23;q34) is associated with dysplasia and a high frequency of flt3 gene mutations.
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Academic Article
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Expression of bcl-3 in chronic lymphocytic leukemia correlates with trisomy 12 and abnormalities of chromosome 19.
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Academic Article
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Biological validation of differentially expressed genes in chronic lymphocytic leukemia identified by applying multiple statistical methods to oligonucleotide microarrays.
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Academic Article
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TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state.
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Academic Article
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Nuclear BCL-10 expression is common in lymphoplasmacytic lymphoma/Waldenstr?m macroglobulinemia and does not correlate with p65 NF-kappaB activation.
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Academic Article
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TaqMan reverse transcriptase-polymerase chain reaction coupled with capillary electrophoresis for quantification and identification of bcr-abl transcript type.
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Academic Article
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Expression of Smac/DIABLO in B-cell non-Hodgkin and Hodgkin lymphomas.
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Academic Article
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NPM-ALK oncogenic kinase promotes cell-cycle progression through activation of JNK/cJun signaling in anaplastic large-cell lymphoma.
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Academic Article
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MALT lymphoma involving the kidney: a report of 10 cases and review of the literature.
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Academic Article
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Splenic marginal zone lymphomas are characterized by loss of interstitial regions of chromosome 7q, 7q31.32 and 7q36.2 that include the protection of telomere 1 (POT1) and sonic hedgehog (SHH) genes.
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Academic Article
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Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma.
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Academic Article
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Cytoplasmic localization of nucleophosmin in bone marrow blasts of acute myeloid leukemia patients is not completely concordant with NPM1 mutation and is not predictive of prognosis.
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Academic Article
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Rapid and reliable confirmation of acute promyelocytic leukemia by immunofluorescence staining with an antipromyelocytic leukemia antibody: the M. D. Anderson Cancer Center experience of 349 patients.
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Academic Article
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HDM4 is overexpressed in mantle cell lymphoma and its inhibition induces p21 expression and apoptosis.
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Academic Article
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LDOC1 mRNA is differentially expressed in chronic lymphocytic leukemia and predicts overall survival in untreated patients.
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Academic Article
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Glioma-associated oncogene homologue 3, a hedgehog transcription factor, is highly expressed in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.
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Academic Article
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Detection of nucleophosmin 1 mutations by quantitative real-time polymerase chain reaction versus capillary electrophoresis: a comparative study.
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Academic Article
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B-cell lymphomas with MYC/8q24 rearrangements and IGH@BCL2/t(14;18)(q32;q21): an aggressive disease with heterogeneous histology, germinal center B-cell immunophenotype and poor outcome.
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Academic Article
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Array comparative genomic hybridization analysis identifies recurrent gain of chromosome 2p25.3 involving the ACP1 and MYCN genes in chronic lymphocytic leukemia.
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Academic Article
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Somatic deletions of the polyA tract in the 3' untranslated region of epidermal growth factor receptor are common in microsatellite instability-high endometrial and colorectal carcinomas.
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Academic Article
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Molecular characterization of de novo Philadelphia chromosome-positive acute myeloid leukemia.
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Academic Article
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Rapid detection and quantitation of BRAF mutations in hairy cell leukemia using a sensitive pyrosequencing assay.
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Academic Article
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Detection of ABCC1 expression in classical Hodgkin lymphoma is associated with increased risk of treatment failure using standard chemotherapy protocols.
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Academic Article
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Over-expression of CYP2E1 mRNA and protein: implications of xenobiotic induced damage in patients with de novo acute myeloid leukemia with inv(16)(p13.1q22); CBF?-MYH11.
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Academic Article
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Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma.
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Academic Article
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Phenotypic evolution in a case of peripheral T-cell lymphoma suggests the presence of tumor heterogeneity.
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Academic Article
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Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.
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Academic Article
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Chromosomal translocation t(14;19) as indicated by bcl-3 rearrangement is a rare phenomenon in non-Hodgkin's lymphoma and chronic lymphocytic leukemia: a molecular genetic analysis of 176 cases.
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Academic Article
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P53 expression in Reed-Sternberg cells does not correlate with gene mutations in Hodgkin's disease.
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Academic Article
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Hodgkin's disease of the esophagus.
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Academic Article
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Detection of Epstein-Barr virus in the L & H cells of nodular lymphocyte predominance Hodgkin's disease: report of a case documented by immunohistochemical, in situ hybridization, and polymerase chain reaction methods.
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Academic Article
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Oncocytic adrenocortical neoplasms: a report of seven cases and review of the literature.
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Academic Article
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Primary anaplastic large cell lymphoma of the small intestine.
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Academic Article
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Acute lymphoblastic leukemia in elderly patients the Philadelphia chromosome may not be a significant adverse prognostic factor.
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Academic Article
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Rapid detection of IgH/BCL2 rearrangement in follicular lymphoma by interphase fluorescence in situ hybridization with bacterial artificial chromosome probes.
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Academic Article
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Apoptotic rate in peripheral T-cell lymphomas. A study using a tissue microarray with validation on full tissue sections.
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Academic Article
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Expression of p27(Kip1) and c-Jun activation binding protein 1 are inversely correlated in systemic anaplastic large cell lymphoma.
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Academic Article
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Characterization of 4 mantle cell lymphoma cell lines.
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Academic Article
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BCL-3 overexpression in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma.
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Academic Article
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Chromosomal translocations involved in non-Hodgkin lymphomas.
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Academic Article
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c-kit is not expressed in Hodgkin disease and anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma.
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Academic Article
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TaqMan RT-PCR assay coupled with capillary electrophoresis for quantification and identification of bcr-abl transcript type.
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Academic Article
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Expression of CD2 in acute promyelocytic leukemia correlates with short form of PML-RARalpha transcripts and poorer prognosis.
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Academic Article
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Methylation of SHP1 gene and loss of SHP1 protein expression are frequent in systemic anaplastic large cell lymphoma.
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Academic Article
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MCL-1 expression in B-cell non-Hodgkin's lymphomas.
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Academic Article
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Inhibition of Akt increases p27Kip1 levels and induces cell cycle arrest in anaplastic large cell lymphoma.
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Academic Article
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Suppressor of cytokine signaling 3 expression in anaplastic large cell lymphoma.
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Academic Article
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Quantitative PCR detection of t(14;18) bcl-2/JH fusion sequences in follicular lymphoma patients: comparison of peripheral blood and bone marrow aspirate samples.
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Academic Article
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Morphologic, cytogenetic, and molecular abnormalities in therapy-related acute promyelocytic leukemia.
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Academic Article
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Differential expression of cyclin D3 in ALK+ and ALK- anaplastic large cell lymphoma.
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Academic Article
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Inhibition of the phosphatidylinositol-3 kinase/Akt promotes G1 cell cycle arrest and apoptosis in Hodgkin lymphoma.
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Academic Article
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Impact of LMP-1 expression on clinical outcome in age-defined subgroups of patients with classical Hodgkin lymphoma.
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Academic Article
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High frequency of NPM1 gene mutations in acute myeloid leukemia with prominent nuclear invaginations ("cuplike" nuclei).
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Academic Article
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Expression of inhibitor of apoptosis proteins in B-cell non-Hodgkin and Hodgkin lymphomas.
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Academic Article
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Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22).
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Academic Article
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Nucleophosmin gene mutations in acute myeloid leukemia.
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Academic Article
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Differential expression of the human MIXL1 gene product in non-Hodgkin and Hodgkin lymphomas.
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Academic Article
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High-grade B-cell lymphoma/leukemia associated with t(14;18) and 8q24/MYC rearrangement: a neoplasm of germinal center immunophenotype with poor prognosis.
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Academic Article
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The helix-loop-helix protein Id2 is expressed differentially and induced by myc in T-cell lymphomas.
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Academic Article
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Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma.
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Academic Article
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Application of COLD-PCR for improved detection of KRAS mutations in clinical samples.
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Academic Article
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Side population of a murine mantle cell lymphoma model contains tumour-initiating cells responsible for lymphoma maintenance and dissemination.
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Academic Article
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Cuplike nuclei (prominent nuclear invaginations) in acute myeloid leukemia are highly associated with FLT3 internal tandem duplication and NPM1 mutation.
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Academic Article
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The therapeutic potential of p53 reactivation by nutlin-3a in ALK+ anaplastic large cell lymphoma with wild-type or mutated p53.
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Academic Article
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Acute promyelocytic leukemia at time of relapse commonly demonstrates cytogenetic evidence of clonal evolution and variability in blast immunophenotypic features.
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Academic Article
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Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-?B-inducing kinase while activating both canonical and alternative nuclear factor-?B pathways.
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Academic Article
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mTOR signaling is activated by FLT3 kinase and promotes survival of FLT3-mutated acute myeloid leukemia cells.
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Academic Article
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Clinical experience with the heat shock protein-90 inhibitor, tanespimycin, in patients with relapsed lymphoma.
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Academic Article
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Immunohistochemical and molecular cytogenetic evaluation of potential targets for tyrosine kinase inhibitors in Langerhans cell histiocytosis.
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Academic Article
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Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an International DLBCL rituximab-CHOP Consortium Program Study.
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Academic Article
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MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program.
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Academic Article
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The clinical importance of moderate/severe bone marrow fibrosis in patients with therapy-related myelodysplastic syndromes.
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Academic Article
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CD30 expression in acute lymphoblastic leukemia as assessed by flow cytometry analysis.
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Academic Article
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MYC/BCL2 double-hit high-grade B-cell lymphoma.
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Academic Article
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MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program.
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Academic Article
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Double hit lymphoma: the MD Anderson Cancer Center clinical experience.
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Academic Article
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Transferrin receptor expression by non-Hodgkin's lymphomas. Correlation with morphologic grade and survival.
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Academic Article
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Splenic marginal zone cell lymphoma. An immunophenotypic and molecular study of five cases.
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Academic Article
|
Gastric lymphoepithelioma-like carcinoma and jejunal B-cell MALT lymphoma with large cell transformation. Demonstration of EBV with identical LMP gene deletions in the carcinoma and large cell lymphoma.
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Academic Article
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Cyclin D1 immunohistochemical staining is useful in distinguishing mantle cell lymphoma from other low-grade B-cell neoplasms in bone marrow.
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Academic Article
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Immunohistochemical detection of E2F-1 in non-Hodgkin's lymphomas: a survey of 124 cases.
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Academic Article
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Dissolution of the lymphoid follicle is a feature of the HHV8+ variant of plasma cell Castleman's disease.
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Academic Article
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BCL-2 is consistently expressed in hyperplastic marginal zones of the spleen, abdominal lymph nodes, and ileal lymphoid tissue.
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Academic Article
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Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma.
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Academic Article
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Immunohistochemical detection of BCL-3 in lymphoid neoplasms: a survey of 353 cases.
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Academic Article
|
p53 gene mutations are uncommon but p53 is commonly expressed in anaplastic large-cell lymphoma.
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Academic Article
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Activation of mammalian target of rapamycin signaling promotes cell cycle progression and protects cells from apoptosis in mantle cell lymphoma.
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Academic Article
|
Inhibition of p53-murine double minute 2 interaction by nutlin-3A stabilizes p53 and induces cell cycle arrest and apoptosis in Hodgkin lymphoma.
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Academic Article
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Comparative analysis of genes regulated in acute myelomonocytic leukemia with and without inv(16)(p13q22) using microarray techniques, real-time PCR, immunohistochemistry, and flow cytometry immunophenotyping.
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Academic Article
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Aberrant EVI1 expression in acute myeloid leukemias associated with the t(3;8)(q26;q24).
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Academic Article
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Expression of helix-loop-helix proteins in classical hodgkin lymphoma: a possible explanation for a characteristic immunophenotype.
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Academic Article
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Sonic hedgehog signaling proteins and ATP-binding cassette G2 are aberrantly expressed in diffuse large B-cell lymphoma.
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Academic Article
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Chronic lymphocytic leukemia with t(14;19)(q32;q13) is characterized by atypical morphologic and immunophenotypic features and distinctive genetic features.
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Academic Article
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A two-gene signature, SKI and SLAMF1, predicts time-to-treatment in previously untreated patients with chronic lymphocytic leukemia.
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Academic Article
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Molecular and clinicopathologic characterization of AML with isolated trisomy 4.
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Academic Article
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Detection of high-frequency and novel DNMT3A mutations in acute myeloid leukemia by high-resolution melting curve analysis.
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Academic Article
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Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma.
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Academic Article
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CXC chemokine receptor 4 expression, CXC chemokine receptor 4 activation, and wild-type nucleophosmin are independently associated with unfavorable prognosis in patients with acute myeloid leukemia.
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Academic Article
|
Determination of lineage and clonality in diffuse lymphomas using the polymerase chain reaction technique.
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Academic Article
|
Primary cutaneous diffuse large B-cell lymphoma: a clinicopathologic study of 15 cases.
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Academic Article
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Epstein-Barr virus-positive B-cell lymphoproliferative disorders arising in immunodeficient patients previously treated with fludarabine for low-grade B-cell neoplasms.
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Academic Article
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Mature B-cell leukemias with more than 55% prolymphocytes: report of 2 cases with Burkitt lymphoma-type chromosomal translocations involving c-myc.
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Academic Article
|
Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia.
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Academic Article
|
Lack of c-kit (CD117) expression in CD30+ lymphomas and lymphomatoid papulosis.
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Academic Article
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Survivin expression predicts poorer prognosis in anaplastic large-cell lymphoma.
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Academic Article
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Acute myeloid leukaemia with FLT3 gene mutations of both internal tandem duplication and point mutation type.
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Academic Article
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The t(14;19)(q32;q13)-positive small B-cell leukaemia: a clinicopathologic and cytogenetic study of seven cases.
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Academic Article
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HDM4 (HDMX) is widely expressed in adult pre-B acute lymphoblastic leukemia and is a potential therapeutic target.
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Academic Article
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8-Aminoadenosine inhibits Akt/mTOR and Erk signaling in mantle cell lymphoma.
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Academic Article
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Immunostaining for rapid diagnosis of acute promyelocytic leukemia with the tetramethylrhodamine-5-isothiocyanate-conjugated anti-promyelocytic leukemia monoclonal antibody PG-M3.
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Academic Article
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Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
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Academic Article
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Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia.
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Academic Article
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Accuracy of serum human epididymis protein 4 in ovarian cancer diagnosis: a systematic review and meta-analysis.
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Academic Article
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Clinical implications of phosphorylated STAT3 expression in De Novo diffuse large B-cell lymphoma.
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Academic Article
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The oncogenic JUNB/CD30 axis contributes to cell cycle deregulation in ALK+ anaplastic large cell lymphoma.
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Academic Article
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Neonatal hypoxic-ischemic encephalopathy reduces c-Fos activation in the rat hippocampus: evidence of a long-lasting effect.
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Academic Article
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Clinical features of de novo acute myeloid leukemia with concurrent DNMT3A, FLT3 and NPM1 mutations.
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Academic Article
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Clinical massively parallel next-generation sequencing analysis of 409 cancer-related genes for mutations and copy number variations in solid tumours.
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Academic Article
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A novel recurrent NPM1-TYK2 gene fusion in cutaneous CD30-positive lymphoproliferative disorders.
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Academic Article
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Epstein-Barr virus-positive plasmacytoma in immunocompetent patients.
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Academic Article
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Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases.
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Academic Article
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Identification of a novel fusion gene, IRF2BP2-RARA, in acute promyelocytic leukemia.
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Academic Article
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Comparison of next-generation sequencing mutation profiling with BRAF and IDH1 mutation-specific immunohistochemistry.
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Academic Article
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The clinical significance of negative flow cytometry immunophenotypic results in a morphologically scored positive bone marrow in patients following treatment for acute myeloid leukemia.
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Academic Article
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Chronic myelomonocytic leukemia with nucleophosmin (NPM1) mutation.
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Academic Article
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MYC cytogenetic status correlates with expression and has prognostic significance in patients with MYC/BCL2 protein double-positive diffuse large B-cell lymphoma.
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Academic Article
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Triple-hit B-cell Lymphoma With MYC, BCL2, and BCL6 Translocations/Rearrangements: Clinicopathologic Features of 11 Cases.
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Academic Article
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Insights from response to tyrosine kinase inhibitor therapy in a rare myeloproliferative neoplasm with CALR mutation and BCR-ABL1.
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Academic Article
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Evaluation of NF-?B subunit expression and signaling pathway activation demonstrates that p52 expression confers better outcome in germinal center B-cell-like diffuse large B-cell lymphoma in association with CD30 and BCL2 functions.
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Academic Article
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Prognostic and biological significance of survivin expression in patients with diffuse large B-cell lymphoma treated with rituximab-CHOP therapy.
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Academic Article
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High-grade B-cell Lymphoma With MYC Rearrangement and Without BCL2 and BCL6 Rearrangements Is Associated With High P53 Expression and a Poor Prognosis.
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Academic Article
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Establishment and characterization of a novel MYC/BCL2 "double-hit" diffuse large B cell lymphoma cell line, RC.
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Academic Article
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Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP.
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Academic Article
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De Novo MYC and BCL2 Double-hit B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) in Pediatric and Young Adult Patients Associated With Poor Prognosis.
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Academic Article
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Cytogenetic landscape and impact in blast phase of chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy.
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Academic Article
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Primary testicular diffuse large B-cell lymphoma displays distinct clinical and biological features for treatment failure in rituximab era: a report from the International PTL Consortium.
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Academic Article
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MYC/BCL6 double-hit lymphoma (DHL): a tumour associated with an aggressive clinical course and poor prognosis.
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Academic Article
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Myeloid neoplasms with isolated isochromosome 17q demonstrate a high frequency of mutations in SETBP1, SRSF2, ASXL1 and NRAS.
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Academic Article
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p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function.
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Academic Article
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Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell lymphoma.
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Academic Article
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Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma.
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Academic Article
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Prognostic impact of history of follicular lymphoma, induction regimen and stem cell transplant in patients with MYC/BCL2 double hit lymphoma.
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Academic Article
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Loss of PRDM1/BLIMP-1 function contributes to poor prognosis of activated B-cell-like diffuse large B-cell lymphoma.
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Academic Article
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BRAF and MAP2K1 mutations in Langerhans cell histiocytosis: a study of 50 cases.
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Academic Article
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Burkitt lymphoma presenting as a mass in the thyroid gland: a clinicopathologic study of 7 cases and review of the literature.
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Academic Article
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CD30 expression and prognostic significance in R-EPOCH-treated patients with diffuse large B-cell lymphoma.
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Academic Article
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Langerhans cell histiocytosis associated with lymphoma: an incidental finding that is not associated with BRAF or MAP2K1 mutations.
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Academic Article
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Well-differentiated systemic mastocytosis showed excellent clinical response to imatinib in the absence of known molecular genetic abnormalities: A case report.
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Academic Article
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Prognostic significance of cytogenetic abnormalities in T-cell prolymphocytic leukemia.
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Academic Article
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Prognostic impact of CD5 expression in diffuse large B-cell lymphoma in patients treated with rituximab-EPOCH.
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Academic Article
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Double-hit follicular lymphoma with MYC and BCL2 translocations: a study of 7 cases with a review of literature.
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Academic Article
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Assessment of CD37 B-cell antigen and cell of origin significantly improves risk prediction in diffuse large B-cell lymphoma.
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Academic Article
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A rare histologic variant of a common lymphoma.
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Academic Article
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Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD.
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Academic Article
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Characteristics and clinical implications of reactive germinal centers in the bone marrow.
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Academic Article
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Myeloproliferative neoplasms with t(8;22)(p11.2;q11.2)/BCR-FGFR1: a meta-analysis of 20 cases shows cytogenetic progression with B-lymphoid blast phase.
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Academic Article
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Outcomes of Patients With Double-Hit Lymphoma Who Achieve First Complete Remission.
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Academic Article
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Mutually exclusive recurrent KRAS and MAP2K1 mutations in Rosai-Dorfman disease.
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Academic Article
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Myeloid neoplasms with concurrent BCR-ABL1 and CBFB rearrangements: A series of 10 cases of a clinically aggressive neoplasm.
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Academic Article
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Additional-structural-chromosomal aberrations are associated with inferior clinical outcome in patients with hyperdiploid multiple myeloma: a single-institution experience.
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Academic Article
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Validation of the 2016 revisions to the WHO classification in lower-risk myelodysplastic syndrome.
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Academic Article
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TCL-1-positive hematogones in a patient with T-cell prolymphocytic leukemia after therapy.
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Academic Article
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Apoptosis signaling and BCL-2 pathways provide opportunities for novel targeted therapeutic strategies in hematologic malignances.
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Academic Article
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CD200 expression in mantle cell lymphoma identifies a unique subgroup of patients with frequent IGHV mutations, absence of SOX11 expression, and an indolent clinical course.
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Academic Article
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Clinical and prognostic significance of e1a2 BCR-ABL1 transcript subtype in chronic myeloid leukemia.
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Academic Article
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Coexistent genetic alterations involving ALK, RET, ROS1 or MET in 15 cases of lung adenocarcinoma.
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Academic Article
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AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma.
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Academic Article
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Comparison of karyotyping, TCL1 fluorescence in situ hybridisation and TCL1 immunohistochemistry in T cell prolymphocytic leukaemia.
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Academic Article
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Chronic myelomonocytic leukemia masquerading as cutaneous indeterminate dendritic cell tumor: Expanding the spectrum of skin lesions in chronic myelomonocytic leukemia.
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Academic Article
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8q24/MYC rearrangement is a recurrent cytogenetic abnormality in blastic plasmacytoid dendritic cell neoplasms.
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Academic Article
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MYC protein expression is an important prognostic factor in acute myeloid leukemia.
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Academic Article
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Strategic Therapeutic Targeting to Overcome Venetoclax Resistance in Aggressive B-cell Lymphomas.
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Academic Article
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Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma.
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Academic Article
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Blastic plasmacytoid dendritic cell neoplasm with unusual morphology, MYC rearrangement and TET2 and DNMT3A mutations.
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Academic Article
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Advances in pathological understanding of high-grade B cell lymphomas.
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Academic Article
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MYC/BCL2/BCL6 triple hit lymphoma: a study of 40 patients with a comparison to MYC/BCL2 and MYC/BCL6 double hit lymphomas.
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Academic Article
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Long-term outcomes and mutation profiling of patients with mantle cell lymphoma (MCL) who discontinued ibrutinib.
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Academic Article
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Genomic aberrations involving 12p/ETV6 are highly prevalent in blastic plasmacytoid dendritic cell neoplasms and might represent early clonal events.
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Academic Article
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Clinical molecular testing for ASXL1 c.1934dupG p.Gly646fs mutation in hematologic neoplasms in the NGS era.
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Academic Article
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Acute myeloid leukemia with t(8;16)(p11.2;p13.3)/KAT6A-CREBBP in adults.
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Academic Article
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t(3;8)(q26.2;q24) Often Leads to MECOM/MYC Rearrangement and Is Commonly Associated with Therapy-Related Myeloid Neoplasms and/or Disease Progression.
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Academic Article
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CD123 expression patterns and selective targeting with a CD123-targeted antibody-drug conjugate (IMGN632) in acute lymphoblastic leukemia.
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Academic Article
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Chronic Myeloid Leukemia: Beyond BCR-ABL1.
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Academic Article
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Relapsed B-acute lymphoblastic leukemia with aberrant myeloperoxidase expression following CAR T-cell therapy: A diagnostic challenge.
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Academic Article
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Myeloproliferative neoplasm with ABL1/ETV6 rearrangement mimics chronic myeloid leukemia and responds to tyrosine kinase inhibitors.
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Academic Article
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Acute myeloid leukemia with t(8;21)(q22;q22.1)/RUNX1-RUNX1T1 and KIT Exon 8 mutation is associated with characteristic mastocytosis and dismal outcomes.
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Concept
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Poly-ADP-Ribose Binding Proteins
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Concept
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Ataxia Telangiectasia Mutated Proteins
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Academic Article
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RAS and TP53 can predict survival in adults with T-cell lymphoblastic leukemia treated with hyper-CVAD.
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Academic Article
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Myeloid neoplasm with eosinophilia and BCR-JAK2/t(9;22)(p24;q11.2) morphologically mimicking chronic myeloid leukemia.
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Academic Article
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Clinical, histopathologic, and immunoarchitectural features of dermatopathic lymphadenopathy: an update.
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Academic Article
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t(11;16)(q23;p13)/KMT2A-CREBBP in hematologic malignancies: presumptive evidence of myelodysplasia or therapy-related neoplasm?
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Academic Article
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T(6;14)(q25;q32) involves BCL11B and is highly associated with mixed-phenotype acute leukemia, T/myeloid.
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Academic Article
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Efficacy of venetoclax in high risk relapsed mantle cell lymphoma (MCL) - outcomes and mutation profile from venetoclax resistant MCL patients.
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Academic Article
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Genotype-phenotype correlation of unusual BCR-ABL1 transcripts in Philadelphia chromosome-positive leukaemia.
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Academic Article
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MYC rearrangement but not extra MYC copies is an independent prognostic factor in patients with mantle cell lymphoma.
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Academic Article
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From the archives of MD Anderson Cancer Center: BCR-ABL1-like B acute lymphoblastic leukemia with IGH/EPOR fusion.
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Academic Article
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Chronic myeloid leukemia with insertion-derived BCR-ABL1 fusion: redefining complex chromosomal abnormalities by correlation of FISH and karyotype predicts prognosis.
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Academic Article
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Langerhans cell sarcoma involving skin and showing epidermotropism: A comprehensive review.
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Academic Article
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Clonal evolution with acquisition of BCR-ABL1 in refractory acute myeloid leukemia post therapy with FLT3-inhibitor.
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Academic Article
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Chronic myeloid leukemia presenting in lymphoblastic crisis, a differential diagnosis with Philadelphia-positive B-lymphoblastic leukemia.
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Academic Article
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LPL deletion is associated with poorer response to ibrutinib-based treatments and overall survival in TP53-deleted chronic lymphocytic leukemia.
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Academic Article
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Anaplastic lymphoma kinase (ALK)-negative anaplastic large cell lymphoma with MYC rearrangement.
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Academic Article
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MYC expression is associated with older age, common morphology, increased MYC copy number, and poorer prognosis in patients with ALK+ anaplastic large cell lymphoma.
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Academic Article
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Acquired MET amplification in non-small cell lung cancer is highly associated with the exposure of EGFR inhibitors and may not affect patients' outcome.
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Academic Article
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MET Amplification (MET/CEP7 Ratio?= 1.8) Is an Independent Poor Prognostic Marker in Patients With Treatment-naive Non-Small-cell Lung Cancer.
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Academic Article
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Disseminated ALK-positive histiocytosis with KIF5B-ALK fusion in an adult.
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Academic Article
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ALK+ large B-cell lymphoma with aberrant expression of CD3.
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Academic Article
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The impact of cell-of-origin, MYC/Bcl-2 dual expression and MYC rearrangement on disease relapse among early stage diffuse large B-cell lymphoma patients treated with combined modality therapy.
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Academic Article
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Myelodysplastic syndrome with t(6;9)(p22;q34.1)/DEK-NUP214 better classified as acute myeloid leukemia? A multicenter study of 107 cases.
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Academic Article
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Flow cytometric immunophenotypic alterations of persistent clonal haematopoiesis in remission bone marrows of patients with NPM1-mutated acute myeloid leukaemia.
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Academic Article
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From the archives of MD Anderson Cancer Center: Concurrent BCR-ABL1 and CRLF2 rearrangements in B-lymphoblast phase of chronic myeloid leukemia.
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Academic Article
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Blastoid high-grade B-cell lymphoma initially presenting in bone marrow: a diagnostic challenge.
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Academic Article
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EBV+ high-grade B cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a multi-institutional study.
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Academic Article
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Non-coding NOTCH1 mutations in chronic lymphocytic leukemia negatively impact prognosis.
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Academic Article
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Cyclin D1 expression in Rosai-Dorfman disease: a near-constant finding that is not invariably associated with mitogen-activated protein kinase/extracellular signal-regulated kinase pathway activation.
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Academic Article
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A rare case of acute megakaryoblastic leukemia with t(11;17)(q23;q21) and KMT2A::MLLT6 fusion.
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Academic Article
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3'CBFB deletion in CBFB-rearranged acute myeloid leukemia retains morphological features associated with inv(16), but patients have higher risk of relapse and may require stem cell transplant.
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Academic Article
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Acute promyelocytic leukemia: Immunophenotype and differential diagnosis by flow cytometry.
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Academic Article
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Clinicopathologic spectrum of myeloid neoplasms with concurrent myeloproliferative neoplasm driver mutations and SRSF2 mutations.
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Academic Article
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Expression pattern and diagnostic utility of BCL11B in mature T- and NK-cell neoplasms.
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Academic Article
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Clinical impact of 5'MYC or 3'MYC gain/loss detected by FISH in patients with aggressive B-cell lymphomas.
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Academic Article
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High-grade B-cell lymphoma (HGBL)-NOS is clinicopathologically and genetically more similar to DLBCL/HGBL-DH than DLBCL.
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Academic Article
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PPP1R7 Is a Novel Translocation Partner of CBFB via t(2;16)(q37;q22) in Acute Myeloid Leukemia.
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Academic Article
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Immunophenotypic and genomic landscape of Richter transformation diffuse large B-cell lymphoma.
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Academic Article
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Plasma cell myeloma with RAS/BRAF mutations is frequently associated with a complex karyotype, advanced stage disease, and poorer prognosis.
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Academic Article
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T-prolymphocytic leukemia: TCL1 or MTCP1 rearrangement is not mandatory to establish diagnosis.
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Academic Article
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Detection of clinically actionable gene fusions by next-generation sequencing-based RNA sequencing of non-small cell lung cancer cytology specimens: A single-center experience with comparison to fluorescence in?situ hybridization.
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Academic Article
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The Clinicopathologic Features and Molecular Signatures of Blastoid High-Grade B Cell Lymphoma, Not Otherwise Specified.
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Academic Article
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Aleukemic Chronic Myeloid Leukemia Without Neutrophilia and Thrombocytosis: A Report From the BCR::ABL1 Pathology Group.
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