"Endothelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
| Descriptor ID |
D016232
|
| MeSH Number(s) |
D12.644.276.400 D12.776.467.400 D23.529.400
|
| Concept/Terms |
Endothelins- Endothelins
- Endothelium-Derived Vasoconstrictor Factors
- Vasoconstrictor Factors, Endothelium-Derived
- Endothelin
|
Below are MeSH descriptors whose meaning is more general than "Endothelins".
Below are MeSH descriptors whose meaning is more specific than "Endothelins".
This graph shows the total number of publications written about "Endothelins" by people in this website by year, and whether "Endothelins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endothelins" by people in Profiles.
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Role of endothelin in the effects of isoprenaline on potassium currents and calsequestrin 2 expression in the heart. Clin Exp Pharmacol Physiol. 2010 May; 37(5-6):557-63.
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Diversity of endothelium-derived vasocontracting factors--arachidonic acid metabolites. Acta Pharmacol Sin. 2003 Nov; 24(11):1065-9.
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Does gender influence human cardiovascular and renal responses to water immersion? J Appl Physiol (1985). 2000 Aug; 89(2):621-8.
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Specific repression of the preproendothelin-1 gene in intracranial arteriovenous malformations. J Neurosurg. 1997 Jan; 86(1):101-8.
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Effects of selected vasoconstrictor agonists on isolated omental artery from premenopausal nonpregnant women and from normal and preeclamptic pregnant women. Am J Obstet Gynecol. 1996 Feb; 174(2):687-93.
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Sequence analysis, chromosomal location, and developmental expression of the mouse preproendothelin-1 gene. Genomics. 1996 Jan 15; 31(2):177-84.
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Pre-eclampsia does not alter the response to endothelin-1 in human omental artery. J Cardiovasc Pharmacol. 1995; 26 Suppl 3:S233-5.
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Uterine contractile responses to endothelin-1 and endothelin receptors are elevated during labor. Biol Reprod. 1994 Oct; 51(4):640-5.
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Role of extracellular calcium and calcium channels in the response of human placental venous smooth muscle to endothelin-1. Am J Obstet Gynecol. 1993 Dec; 169(6):1427-30.
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Contractile effect of endothelin in human placental veins: role of endothelium prostaglandins and thromboxane. Am J Obstet Gynecol. 1993 Oct; 169(4):919-24.