Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
"Basic Helix-Loop-Helix Leucine Zipper Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors that contain regions rich in basic residues, LEUCINE ZIPPER domains, and HELIX-LOOP-HELIX MOTIFS.
| Descriptor ID |
D051778
|
| MeSH Number(s) |
D12.776.260.103.500 D12.776.260.108.092 D12.776.930.125.500 D12.776.930.127.092
|
| Concept/Terms |
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Basic Helix Loop Helix Leucine Zipper Transcription Factors
- BHLH-Zip Transcription Factors
- BHLH Zip Transcription Factors
- Transcription Factors, BHLH-Zip
- BHLHLZ Transcription Factors
- Transcription Factors, BHLHLZ
|
Below are MeSH descriptors whose meaning is more general than "Basic Helix-Loop-Helix Leucine Zipper Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Basic Helix-Loop-Helix Leucine Zipper Transcription Factors".
This graph shows the total number of publications written about "Basic Helix-Loop-Helix Leucine Zipper Transcription Factors" by people in this website by year, and whether "Basic Helix-Loop-Helix Leucine Zipper Transcription Factors" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 6 | 1 | 7 |
| 2012 | 3 | 2 | 5 |
| 2013 | 8 | 1 | 9 |
| 2014 | 3 | 3 | 6 |
| 2015 | 3 | 3 | 6 |
| 2016 | 11 | 4 | 15 |
| 2017 | 8 | 3 | 11 |
| 2018 | 10 | 4 | 14 |
| 2019 | 7 | 5 | 12 |
| 2020 | 10 | 1 | 11 |
| 2021 | 7 | 2 | 9 |
| 2022 | 2 | 0 | 2 |
| 2023 | 2 | 10 | 12 |
| 2024 | 8 | 2 | 10 |
| 2025 | 9 | 1 | 10 |
| 2026 | 3 | 0 | 3 |
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Below are the most recent publications written about "Basic Helix-Loop-Helix Leucine Zipper Transcription Factors" by people in Profiles.
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The Non-Canonical ChREBPa Activity Suppresses the Activation of Hepatic Stellate Cells and Liver Fibrosis by Antagonizing TGF-?-E2F1 Axis. Adv Sci (Weinh). 2025 Aug; 12(29):e15032.
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Folliculin Deletion in the Mouse Kidney Results in Cystogenesis of the Loops of Henle via Aberrant TFEB Activation. Am J Pathol. 2025 09; 195(9):1643-1659.
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Glucose-Sensing Carbohydrate Response Element-Binding Protein in the Pathogenesis of Diabetic Retinopathy. Cells. 2025 01 13; 14(2).
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Suppression of hepatic ChREBP?-CYP2C50 axis-driven fatty acid oxidation sensitizes mice to diet-induced MASLD/MASH. Mol Metab. 2024 07; 85:101957.
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TFEB-mediated lysosomal exocytosis alleviates high-fat diet-induced lipotoxicity in the kidney. JCI Insight. 2023 02 22; 8(4).
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HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis. JCI Insight. 2023 01 10; 8(1).
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Maladaptive positive feedback production of ChREBP? underlies glucotoxic ?-cell failure. Nat Commun. 2022 07 30; 13(1):4423.
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Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations. Circ Genom Precis Med. 2021 08; 14(4):e003288.
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Insulin action, type 2 diabetes, and branched-chain amino acids: A two-way street. Mol Metab. 2021 10; 52:101261.
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Adaptive and maladaptive roles for ChREBP in the liver and pancreatic islets. J Biol Chem. 2021 Jan-Jun; 296:100623.