"Cefotaxime" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semisynthetic broad-spectrum cephalosporin.
| Descriptor ID |
D002439
|
| MeSH Number(s) |
D02.065.589.099.249.190.190 D02.886.665.074.190.190 D03.633.100.300.249.190.190
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cefotaxime".
Below are MeSH descriptors whose meaning is more specific than "Cefotaxime".
This graph shows the total number of publications written about "Cefotaxime" by people in this website by year, and whether "Cefotaxime" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 |
| 1996 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2023 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Cefotaxime" by people in Profiles.
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Mutagenesis and structural analysis reveal the CTX-M ?-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J Biol Chem. 2023 05; 299(5):104630.
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Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M ?-lactamase. Commun Biol. 2023 01 12; 6(1):35.
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Differential active site requirements for NDM-1 ?-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics. Nat Commun. 2018 10 30; 9(1):4524.
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Synergistic effects of functionally distinct substitutions in ?-lactamase variants shed light on the evolution of bacterial drug resistance. J Biol Chem. 2018 11 16; 293(46):17971-17984.
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Molecular basis for the catalytic specificity of the CTX-M extended-spectrum ?-lactamases. Biochemistry. 2015 Jan 20; 54(2):447-57.
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Prevalence and molecular characterization of extended-spectrum-?-lactamase-producing Enterobacteriaceae in a pediatric patient population. Antimicrob Agents Chemother. 2012 Sep; 56(9):4765-70.
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Inspissated bile syndrome in a neonate treated with cefotaxime: sonographic aid to diagnosis, management, and follow-up. J Ultrasound Med. 2009 Apr; 28(4):541-4.
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Varicella reactivation presenting as shingles and aseptic meningitis in an immunocompetent 11-year-old boy. Clin Pediatr (Phila). 2009 May; 48(4):435-7.
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Unusual soft tissue manifestations of Neisseria meningitidis infections. Clin Pediatr (Phila). 2008 May; 47(4):400-3.
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Impact of the pneumococcal conjugate vaccine on serotype distribution and antimicrobial resistance of invasive Streptococcus pneumoniae isolates in Dallas, TX, children from 1999 through 2005. Pediatr Infect Dis J. 2007 Jun; 26(6):461-7.