"Cystatins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homologous group of endogenous CYSTEINE PROTEINASE INHIBITORS. The cystatins inhibit most CYSTEINE ENDOPEPTIDASES such as PAPAIN, and other peptidases which have a sulfhydryl group at the active site.
| Descriptor ID |
D015891
|
| MeSH Number(s) |
D12.776.215
|
| Concept/Terms |
Type 3 Cystatins- Type 3 Cystatins
- Cystatins, Type 3
- Type III Cystatins
- Cystatins, Type III
Type 2 Cystatins- Type 2 Cystatins
- Cystatins, Type 2
- Type II Cystatins
- Cystatins, Type II
Type 1 Cystatins- Type 1 Cystatins
- Cystatins, Type 1
- Type I Cystatins
- Cystatins, Type I
- Stefins
|
Below are MeSH descriptors whose meaning is more general than "Cystatins".
Below are MeSH descriptors whose meaning is more specific than "Cystatins".
This graph shows the total number of publications written about "Cystatins" by people in this website by year, and whether "Cystatins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cystatins" by people in Profiles.
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Schistosoma japonicum cystatin alleviates paraquat poisoning caused acute lung injury in mice through activating regulatory macrophages. Ecotoxicol Environ Saf. 2024 Aug; 281:116615.
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Trichinella spiralis cystatin alleviates polymicrobial sepsis through activating regulatory macrophages. Int Immunopharmacol. 2022 Aug; 109:108907.
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Urine ALCAM, PF4 and VCAM-1 Surpass Conventional Metrics in Identifying Nephritis Disease Activity in Childhood-Onset Systemic Lupus Erythematosus. Front Immunol. 2022; 13:885307.
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Schistosoma japonicum Cystatin Alleviates Sepsis Through Activating Regulatory Macrophages. Front Cell Infect Microbiol. 2021; 11:617461.
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Therapeutic efficacy of Schistosoma japonicum cystatin on sepsis-induced cardiomyopathy in a mouse model. Parasit Vectors. 2020 May 18; 13(1):260.
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Therapeutic effect of Schistosoma japonicum cystatin on bacterial sepsis in mice. Parasit Vectors. 2017 May 08; 10(1):222.
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Primary tumour expression of the cysteine cathepsin inhibitor Stefin A inhibits distant metastasis in breast cancer. J Pathol. 2008 Feb; 214(3):337-46.
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Renal impairment and outcomes in heart failure: systematic review and meta-analysis. J Am Coll Cardiol. 2006 May 16; 47(10):1987-96.
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Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem. 2006 Mar 03; 281(9):6020-9.
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Homology model and molecular dynamics simulation of carp ovum cystatin. Biotechnol Prog. 2005 Jul-Aug; 21(4):1315-20.