"Cathepsin L" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously-expressed cysteine protease that plays an enzymatic role in POST-TRANSLATIONAL PROTEIN PROCESSING of proteins within SECRETORY GRANULES.
| Descriptor ID |
D056668
|
| MeSH Number(s) |
D08.811.277.656.224.407 D08.811.277.656.262.500.157 D08.811.277.656.300.200.157
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathepsin L".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin L".
This graph shows the total number of publications written about "Cathepsin L" by people in this website by year, and whether "Cathepsin L" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsin L" by people in Profiles.
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Protecting glomerulus: role of angiotensin-II type 2 receptor. Clin Sci (Lond). 2022 10 28; 136(20):1467-1470.
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Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nat Med. 2021 03; 27(3):546-559.
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Cancer-bone microenvironmental interactions promotes STAT3 signaling. Mol Carcinog. 2019 08; 58(8):1349-1361.
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CCAAT-displacement protein/cut homeobox transcription factor (CUX1) represses estrogen receptor-alpha (ER-a) in triple-negative breast cancer cells and can be antagonized by muscadine grape skin extract (MSKE). PLoS One. 2019; 14(4):e0214844.
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Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments. Bioorg Med Chem Lett. 2019 01 01; 29(1):36-39.
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Association of Epithelial Mesenchymal Transition with prostate and breast health disparities. PLoS One. 2018; 13(9):e0203855.
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Small-molecule inhibitors of cathepsin L incorporating functionalized ring-fused molecular frameworks. Bioorg Med Chem Lett. 2013 May 01; 23(9):2801-7.
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Protective role of cathepsin L in mouse skin carcinogenesis. Mol Carcinog. 2012 Apr; 51(4):352-61.
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Role of urinary cathepsin B and L in the detection of bladder urothelial cell carcinoma. J Urol. 2008 Feb; 179(2):478-84; discussion 484.
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Lysosomes and trivalent arsenic treatment in acute promyelocytic leukemia. J Natl Cancer Inst. 2007 Jan 03; 99(1):41-52.