"Osteonectin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Non-collagenous, calcium-binding glycoprotein of developing bone. It links collagen to mineral in the bone matrix. In the synonym SPARC glycoprotein, the acronym stands for Secreted Protein, Acidic and Rich in Cysteine.
Descriptor ID |
D015676
|
MeSH Number(s) |
D12.776.157.125.715 D12.776.395.600
|
Concept/Terms |
Osteonectin- Osteonectin
- SPARC Glycoprotein
- BM-40
- Basement Membrane Tumor Protein
- BM 40 Protein
|
Below are MeSH descriptors whose meaning is more general than "Osteonectin".
Below are MeSH descriptors whose meaning is more specific than "Osteonectin".
This graph shows the total number of publications written about "Osteonectin" by people in this website by year, and whether "Osteonectin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 1 | 1 |
1996 | 2 | 1 | 3 |
1997 | 2 | 0 | 2 |
2000 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2007 | 2 | 1 | 3 |
2009 | 1 | 0 | 1 |
2010 | 2 | 3 | 5 |
2011 | 0 | 1 | 1 |
2013 | 1 | 1 | 2 |
2014 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2018 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Osteonectin" by people in Profiles.
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The Development and Initial Findings of A Study of a Prospective Adult Research Cohort with Inflammatory Bowel Disease (SPARC IBD). Inflamm Bowel Dis. 2022 02 01; 28(2):192-199.
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SOX8 Affects Tumoral SPARC Expression by Regulating EZH2 to Attenuate Effectiveness of albumin-bound paclitaxel in PDAC. Int J Biol Sci. 2022; 18(3):911-922.
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Summary of expression of SPARC protein in cutaneous vascular neoplasms and mimickers. Ann Diagn Pathol. 2018 Jun; 34:151-154.
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Single-cell mRNA profiling reveals transcriptional heterogeneity among pancreatic circulating tumour cells. BMC Cancer. 2017 05 31; 17(1):390.
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Loss of SPARC dysregulates basal lamina assembly to disrupt larval fat body homeostasis in Drosophila melanogaster. Dev Dyn. 2015 Apr; 244(4):540-52.
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SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome. J Clin Invest. 2014 Apr; 124(4):1512-24.
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Elevated plasma SPARC levels are associated with insulin resistance, dyslipidemia, and inflammation in gestational diabetes mellitus. PLoS One. 2013; 8(12):e81615.
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Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma. Blood. 2013 Jul 11; 122(2):219-26.
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A comparison between osteogenic differentiation of human unrestricted somatic stem cells and mesenchymal stem cells from bone marrow and adipose tissue. Biotechnol Lett. 2011 Jun; 33(6):1257-64.
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Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome. PLoS One. 2010 Nov 30; 5(11):e15074.