"Synaptotagmins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of vesicular transport proteins characterized by an N-terminal transmembrane region and two C-terminal calcium-binding domains.
| Descriptor ID |
D050857
|
| MeSH Number(s) |
D12.776.157.125.825 D12.776.543.990.850
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synaptotagmins".
Below are MeSH descriptors whose meaning is more specific than "Synaptotagmins".
This graph shows the total number of publications written about "Synaptotagmins" by people in this website by year, and whether "Synaptotagmins" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synaptotagmins" by people in Profiles.
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Impad1 and Syt11 work in an epistatic pathway that regulates EMT-mediated vesicular trafficking to drive lung cancer invasion and metastasis. Cell Rep. 2022 09 27; 40(13):111429.
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Synaptotagmin-7 deficiency induces mania-like behavioral abnormalities through attenuating GluN2B activity. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31438-31447.
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Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. Proc Natl Acad Sci U S A. 2020 02 25; 117(8):4392-4399.
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Cisplatin treatment induces attention deficits and impairs synaptic integrity in the prefrontal cortex in mice. Sci Rep. 2018 11 27; 8(1):17400.
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The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission. Cell Rep. 2017 12 26; 21(13):3794-3806.
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Synaptotagmin10-Cre, a driver to disrupt clock genes in the SCN. J Biol Rhythms. 2011 Oct; 26(5):379-89.
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Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. PLoS One. 2010 Sep 02; 5(9).
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Distinct roles for two synaptotagmin isoforms in synchronous and asynchronous transmitter release at zebrafish neuromuscular junction. Proc Natl Acad Sci U S A. 2010 Aug 03; 107(31):13906-11.
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Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol. 2006 Mar; 13(3):209-17.
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Synaptotagmin I, a Ca2+ sensor for neurotransmitter release. Trends Neurosci. 2003 Aug; 26(8):413-22.