Nuclear Receptor Subfamily 1, Group F, Member 3
"Nuclear Receptor Subfamily 1, Group F, Member 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An orphan nuclear receptor found in the THYMUS where it plays a role in regulating the development and maturation of thymocytes. An isoform of this protein, referred to as RORgammaT, is produced by an alternatively transcribed mRNA.
| Descriptor ID |
D057132
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| MeSH Number(s) |
D12.776.260.643.182 D12.776.826.209.182
|
| Concept/Terms |
Nuclear Receptor Subfamily 1, Group F, Member 3- Nuclear Receptor Subfamily 1, Group F, Member 3
- Nuclear Receptor RZR-gamma
- Nuclear Receptor RZR gamma
- Receptor RZR-gamma, Nuclear
- ROR-gamma
- Orphan Nuclear Receptor ROR-gamma
- Orphan Nuclear Receptor ROR gamma
- RAR-related Orphan Receptor C
- RAR related Orphan Receptor C
- ROR-C Receptors
- ROR C Receptors
- Nuclear Receptor NR1F3
- Receptor NR1F3, Nuclear
- Orphan Nuclear Receptor NR1F3
|
Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group F, Member 3".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group F, Member 3".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group F, Member 3" by people in this website by year, and whether "Nuclear Receptor Subfamily 1, Group F, Member 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group F, Member 3" by people in Profiles.
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Transcription factor TCF1 binds to ROR?t and orchestrates a regulatory network that determines homeostatic Th17 cell state. Immunity. 2024 11 12; 57(11):2565-2582.e6.
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Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of ROR?t. Elife. 2024 May 09; 13.
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Differential Upregulation of Th1/Th17-Associated Proteins and PD-L1 in Granulomatous Mycosis Fungoides. Cells. 2024 02 27; 13(5).
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Gut Inflammation in Axial Spondyloarthritis Patients is Characterized by a Marked Type 17 Skewed Mucosal Innate-like T Cell Signature. Arthritis Rheumatol. 2023 11; 75(11):1969-1982.
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ROR?t inhibition ameliorates IL-23 driven experimental psoriatic arthritis by predominantly modulating ?d-T cells. Rheumatology (Oxford). 2023 09 01; 62(9):3169-3178.
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Aryl Hydrocarbon Receptor Activation Ameliorates Acute Respiratory Distress Syndrome through Regulation of Th17 and Th22 Cells in the Lungs. mBio. 2023 04 25; 14(2):e0313722.
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Mining the microbiota to identify gut commensals modulating neuroinflammation in a mouse model of multiple sclerosis. Microbiome. 2022 10 17; 10(1):174.
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Liver X receptor regulates Th17 and ROR?t+ Treg cells by distinct mechanisms. Mucosal Immunol. 2021 03; 14(2):411-419.
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Close homolog of L1-deficient ameliorates inflammatory bowel disease by regulating the balance of Th17/Treg. Gene. 2020 Oct 05; 757:144931.
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Directed differentiation of regulatory T cells from naive T cells and prevention of their inflammation-mediated instability using small molecules. Clin Exp Immunol. 2020 08; 201(2):205-221.