Nuclear Receptor Subfamily 1, Group F, Member 1
"Nuclear Receptor Subfamily 1, Group F, Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.
| Descriptor ID |
D057094
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| MeSH Number(s) |
D12.776.189.437 D12.776.260.643.100 D12.776.826.209.100
|
| Concept/Terms |
Nuclear Receptor Subfamily 1, Group F, Member 1- Nuclear Receptor Subfamily 1, Group F, Member 1
- Retinoid-Related Orphan Receptor-alpha
- Retinoid Related Orphan Receptor alpha
- RAR-Related Orphan Receptor A
- RAR Related Orphan Receptor A
- Nuclear Receptor NR1F1
- NR1F1, Nuclear Receptor
- Receptor NR1F1, Nuclear
- Nuclear Receptor ROR-alpha
- Nuclear Receptor ROR alpha
Retinoid-Related Orphan Receptor-alpha4- Retinoid-Related Orphan Receptor-alpha4
- Retinoid Related Orphan Receptor alpha4
- Nuclear Receptor RZR-alpha
- Nuclear Receptor RZR alpha
- RZR-alpha, Nuclear Receptor
|
Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group F, Member 1".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group F, Member 1".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group F, Member 1" by people in this website by year, and whether "Nuclear Receptor Subfamily 1, Group F, Member 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2015 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group F, Member 1" by people in Profiles.
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Restoration of the molecular clock is tumor suppressive in neuroblastoma. Nat Commun. 2021 06 28; 12(1):4006.
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Cardiolipin Synthesis in Skeletal Muscle Is Rhythmic and Modifiable by Age and Diet. Oxid Med Cell Longev. 2020; 2020:5304768.
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Nobiletin fortifies mitochondrial respiration in skeletal muscle to promote healthy aging against metabolic challenge. Nat Commun. 2019 08 28; 10(1):3923.
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Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease. PLoS One. 2019; 14(7):e0218111.
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Genome-wide association study identifies genes associated with neuropathy in patients with head and neck cancer. Sci Rep. 2018 06 08; 8(1):8789.
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Genetic variants in RORA and DNMT1 associated with cutaneous melanoma survival. Int J Cancer. 2018 06 01; 142(11):2303-2312.
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The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORa/?. Genes Dev. 2017 06 15; 31(12):1202-1211.
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The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome. Cell Metab. 2016 Apr 12; 23(4):610-21.
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Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading. Mol Cell. 2015 Dec 03; 60(5):769-783.
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GENE REGULATION. Discrete functions of nuclear receptor Rev-erba couple metabolism to the clock. Science. 2015 Jun 26; 348(6242):1488-92.