Nuclear Receptor Subfamily 6, Group A, Member 1
"Nuclear Receptor Subfamily 6, Group A, Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An orphan nuclear receptor expressed mainly in the GERM CELLS of GONADS. It functions as a transcription factor that binds to a direct repeat of the sequence AGGTCA and may play a role in the regulation of EMBRYOGENESIS and germ cell differentiation.
| Descriptor ID |
D057136
|
| MeSH Number(s) |
D12.776.260.643.572 D12.776.826.209.572
|
| Concept/Terms |
Nuclear Receptor Subfamily 6, Group A, Member 1- Nuclear Receptor Subfamily 6, Group A, Member 1
- Retinoid Receptor-Related Testis-Associated Receptor
- Retinoid Receptor Related Testis Associated Receptor
- Nuclear Receptor NR6A1
- Retinoid Receptor Related Testis Specific Receptor
- Germ Cell Nuclear Factor
- Neuronal Cell Nuclear Factor
|
Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 6, Group A, Member 1".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 6, Group A, Member 1".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 6, Group A, Member 1" by people in this website by year, and whether "Nuclear Receptor Subfamily 6, Group A, Member 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 6, Group A, Member 1" by people in Profiles.
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Candidate genes for premature ovarian failure. Curr Med Chem. 2007; 14(3):353-7.
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Evolutionary trace-based peptides identify a novel asymmetric interaction that mediates oligomerization in nuclear receptors. J Biol Chem. 2005 Sep 09; 280(36):31818-29.
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GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility. EMBO J. 2003 Aug 15; 22(16):4070-81.
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The embryonic function of germ cell nuclear factor is dependent on the DNA binding domain. J Biol Chem. 2002 Dec 27; 277(52):50660-7.
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Physiological function of the orphans GCNF and COUP-TF. Trends Endocrinol Metab. 2001 Aug; 12(6):247-51.
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Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan; 21(2):663-77.