Nuclear Receptor Subfamily 1, Group D, Member 1
"Nuclear Receptor Subfamily 1, Group D, Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.
| Descriptor ID |
D056953
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| MeSH Number(s) |
D12.776.189.300 D12.776.260.643.080 D12.776.826.209.080
|
| Concept/Terms |
Nuclear Receptor Subfamily 1, Group D, Member 1- Nuclear Receptor Subfamily 1, Group D, Member 1
- Rev-erb-alpha Nuclear Receptors
- Nuclear Receptors, Rev-erb-alpha
- Rev erb alpha Nuclear Receptors
- V-erbA-Related Protein EAR-1
- V erbA Related Protein EAR 1
- Nuclear Receptor NR1D1
- NR1D1, Nuclear Receptor
- Receptor NR1D1, Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group D, Member 1".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group D, Member 1".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group D, Member 1" by people in this website by year, and whether "Nuclear Receptor Subfamily 1, Group D, Member 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 1 | 2 |
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Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group D, Member 1" by people in Profiles.
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An intrinsically disordered region controlling condensation of a circadian clock component and rhythmic transcription in the liver. Mol Cell. 2023 10 05; 83(19):3457-3469.e7.
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Hepatocyte SREBP signaling mediates clock communication within the liver. J Clin Invest. 2023 04 17; 133(8).
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Inhibition of Rev-erba ameliorates muscular dystrophy. Exp Cell Res. 2021 09 15; 406(2):112766.
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REV-ERB in GABAergic neurons controls diurnal hepatic insulin sensitivity. Nature. 2021 04; 592(7856):763-767.
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The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020 09 11; 369(6509):1388-1394.
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Keeping the autophagy tempo. Autophagy. 2019 10; 15(10):1854-1856.
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Nutrient-sensitive transcription factors TFEB and TFE3 couple autophagy and metabolism to the peripheral clock. EMBO J. 2019 06 17; 38(12).
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The Nuclear Receptor and Clock Repressor Rev-erba Suppresses Myogenesis. Sci Rep. 2019 03 14; 9(1):4585.
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REV-ERBa ameliorates heart failure through transcription repression. JCI Insight. 2017 09 07; 2(17).
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HNF6 and Rev-erba integrate hepatic lipid metabolism by overlapping and distinct transcriptional mechanisms. Genes Dev. 2016 07 15; 30(14):1636-44.