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HUNG, MIEN-CHIE
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Academic Article Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells.
Academic Article A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma.
Academic Article beta-catenin nuclear localization is associated with grade in ovarian serous carcinoma.
Academic Article Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.
Academic Article External control of Her2 expression and cancer cell growth by targeting a Ras-linked coactivator.
Academic Article Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival.
Academic Article Selective activation of ceruloplasmin promoter in ovarian tumors: potential use for gene therapy.
Academic Article Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer.
Academic Article Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival.
Academic Article Interferon-inducible protein IFIXalpha inhibits cell invasion by upregulating the metastasis suppressor maspin.
Academic Article Expanding the arsenal: metformin for the treatment of triple-negative breast cancer?
Academic Article SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization.
Academic Article 14-3-3zeta overexpression defines high risk for breast cancer recurrence and promotes cancer cell survival.
Academic Article Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation.
Academic Article Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.
Concept Precursor Cell Lymphoblastic Leukemia-Lymphoma
Concept Jurkat Cells
Concept Cell Movement
Concept Leukemia, T-Cell
Concept Hematopoietic Stem Cells
Concept Cell Death
Concept Active Transport, Cell Nucleus
Concept Carcinoma, Non-Small-Cell Lung
Concept NK Cell Lectin-Like Receptor Subfamily K
Concept Epithelial Cells
Concept Cell Lineage
Concept Neoplastic Stem Cells
Concept Hematopoietic Stem Cell Transplantation
Concept HeLa Cells
Concept KB Cells
Concept Cell Nucleus
Concept Cell Division
Concept COS Cells
Concept Resting Phase, Cell Cycle
Concept NIH 3T3 Cells
Concept Dendritic Cells
Concept Cell Cycle Proteins
Concept Cell Cycle
Concept Cell Membrane
Concept HL-60 Cells
Concept Cell Culture Techniques
Concept Cell Transdifferentiation
Concept Stem Cell Factor
Concept K562 Cells
Concept Cell Transformation, Neoplastic
Concept Receptors, Cell Surface
Concept Cell Survival
Concept Cell Communication
Concept Cell Adhesion
Concept Cell Adhesion Molecules
Concept Endothelial Cells
Concept Cell Aggregation
Concept CHO Cells
Concept Carcinoma, Squamous Cell
Concept Cell Adhesion Molecules, Neuronal
Concept Induced Pluripotent Stem Cells
Concept Proliferating Cell Nuclear Antigen
Concept Cell Size
Concept Cell Migration Assays
Concept Embryonic Stem Cells
Concept Cell Membrane Permeability
Concept Cell Growth Processes
Concept Cell Line
Concept Cell Compartmentation
Concept 3T3 Cells
Concept Tumor Stem Cell Assay
Concept Tumor Cells, Cultured
Concept Cell Differentiation
Concept Cell Line, Transformed
Concept Hep G2 Cells
Concept Cells
Concept Pluripotent Stem Cells
Concept Swiss 3T3 Cells
Concept U937 Cells
Concept HCT116 Cells
Concept Killer Cells, Natural
Concept Cell Line, Tumor
Concept Cell Fractionation
Concept Cell Polarity
Concept HT29 Cells
Concept Cells, Cultured
Concept Stem Cells
Concept Cell Hypoxia
Concept Cell Proliferation
Academic Article IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway.
Academic Article ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation.
Academic Article Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer.
Academic Article Different redox states in malignant and nonmalignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol.
Academic Article RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus.
Academic Article Recombinant human erythropoietin antagonizes trastuzumab treatment of breast cancer cells via Jak2-mediated Src activation and PTEN inactivation.
Academic Article Crosstalk between Arg?1175 methylation and Tyr?1173 phosphorylation negatively modulates EGFR-mediated ERK activation.
Academic Article Nuclear translocation of epidermal growth factor receptor by Akt-dependent phosphorylation enhances breast cancer-resistant protein expression in gefitinib-resistant cells.
Academic Article Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes.
Academic Article Elevated BCRP/ABCG2 expression confers acquired resistance to gefitinib in wild-type EGFR-expressing cells.
Academic Article EGFR-SGLT1 interaction does not respond to EGFR modulators, but inhibition of SGLT1 sensitizes prostate cancer cells to EGFR tyrosine kinase inhibitors.
Academic Article APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.
Academic Article TRIM24 links a non-canonical histone signature to breast cancer.
Academic Article A tumorigenic factor interactome connected through tumor suppressor microRNA-198 in human pancreatic cancer.
Academic Article Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis.
Academic Article The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis.
Academic Article Sustained activation of SMAD3/SMAD4 by FOXM1 promotes TGF-?-dependent cancer metastasis.
Academic Article miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion.
Academic Article Molecular mechanisms in Barrett's metaplasia and its progression.
Academic Article Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.
Academic Article Hippo coactivator YAP1 upregulates SOX9 and endows esophageal cancer cells with stem-like properties.
Academic Article Definition of PKC-a, CDK6, and MET as therapeutic targets in triple-negative breast cancer.
Academic Article ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1.
Academic Article Xenoestrogen-induced regulation of EZH2 and histone methylation via estrogen receptor signaling to PI3K/AKT.
Academic Article Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer.
Academic Article lncRNA directs cooperative epigenetic regulation downstream of chemokine signals.
Academic Article 14-3-3? turns TGF-?'s function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2.
Academic Article Inhibition of intratracheal lung cancer development by systemic delivery of E1A.
Academic Article Adenovirus 5 E1A-mediated tumor suppression associated with E1A-mediated apoptosis in vivo.
Academic Article High tumoral maspin expression is associated with improved survival of patients with oral squamous cell carcinoma.
Academic Article Systemic tumor suppression by the proapoptotic gene bik.
Academic Article Dysregulation of cellular signaling by HER2/neu in breast cancer.
Academic Article Determinants of rapamycin sensitivity in breast cancer cells.
Academic Article A delayed chemically induced tumorigenesis in Brca2 mutant mice.
Academic Article IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a.
Academic Article Phosphorylation/cytoplasmic localization of p21Cip1/WAF1 is associated with HER2/neu overexpression and provides a novel combination predictor for poor prognosis in breast cancer patients.
Academic Article Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition.
Academic Article Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells.
Academic Article Wnt, hedgehog and snail: sister pathways that control by GSK-3beta and beta-Trcp in the regulation of metastasis.
Academic Article Suppression of pancreatic tumor progression by systemic delivery of a pancreatic-cancer-specific promoter driven Bik mutant.
Academic Article EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization.
Academic Article Cytoplasmic/nuclear shuttling and tumor progression.
Academic Article AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model.
Academic Article The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells.
Academic Article MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation.
Academic Article Molecular signatures of metaplastic carcinoma of the breast by large-scale transcriptional profiling: identification of genes potentially related to epithelial-mesenchymal transition.
Academic Article Kr?ppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion.
Academic Article Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression.
Academic Article GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers.
Academic Article IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.
Academic Article Targeting YB-1 in HER-2 overexpressing breast cancer cells induces apoptosis via the mTOR/STAT3 pathway and suppresses tumor growth in mice.
Academic Article A new fork for clinical application: targeting forkhead transcription factors in cancer.
Academic Article Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.
Academic Article Phosphorylation of ARD1 by IKKbeta contributes to its destabilization and degradation.
Academic Article Antitumor agents 270. Novel substituted 6-phenyl-4H-furo[3,2-c]pyran-4-one derivatives as potent and highly selective anti-breast cancer agents.
Academic Article COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport.
Academic Article Vimentin is a novel AKT1 target mediating motility and invasion.
Academic Article Rapid detection of two-protein interaction with a single fluorophore by using a microfluidic device.
Academic Article The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus.
Academic Article Controlled extracellular matrix degradation in breast cancer tumors improves therapy by trastuzumab.
Academic Article BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment.
Academic Article Identification of a GaG??, AKT and PKCa signalome associated with invasive growth in two genetic models of human breast cancer cell epithelial-to-mesenchymal transition.
Academic Article In vivo targeting of ADAM9 gene expression using lentivirus-delivered shRNA suppresses prostate cancer growth by regulating REG4 dependent cell cycle progression.
Academic Article Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells.
Academic Article Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.
Academic Article RASAL2: wrestling in the combat of Ras activation.
Academic Article miR326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression.
Academic Article Sensitization of HER-2/neu-overexpressing non-small cell lung cancer cells to chemotherapeutic drugs by tyrosine kinase inhibitor emodin.
Academic Article Overexpression of c-erbB-2/neu in breast cancer cells confers increased resistance to Taxol via mdr-1-independent mechanisms.
Academic Article Overexpression of both p185c-erbB2 and p170mdr-1 renders breast cancer cells highly resistant to taxol.
Academic Article Tyrosine kinase inhibitors, emodin and its derivative repress HER-2/neu-induced cellular transformation and metastasis-associated properties.
Academic Article Ceramide does not act as a general second messenger for ultraviolet-induced apoptosis.
Academic Article Expression profile of tyrosine kinases in breast cancer.
Academic Article Role for the double-stranded RNA activated protein kinase PKR in E2F-1-induced apoptosis.
Academic Article Regulation of the activity of p38 mitogen-activated protein kinase by Akt in cancer and adenoviral protein E1A-mediated sensitization to apoptosis.
Academic Article Adenovirus type 5 E1A sensitizes hepatocellular carcinoma cells to gemcitabine.
Academic Article Crossregulation of NF-kappaB by the APC/GSK-3beta/beta-catenin pathway.
Academic Article Upregulation of IKKalpha/IKKbeta by integrin-linked kinase is required for HER2/neu-induced NF-kappaB antiapoptotic pathway.
Academic Article The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells.
Academic Article A new role of protein phosphatase 2a in adenoviral E1A protein-mediated sensitization to anticancer drug-induced apoptosis in human breast cancer cells.
Academic Article Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis.
Academic Article Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity.
Academic Article Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth.
Academic Article Signaling intricacies take center stage in cancer cells.
Academic Article E1A sensitizes cancer cells to TRAIL-induced apoptosis through enhancement of caspase activation.
Academic Article When all colonies are blue.
Academic Article Co-regulation of B-Myb expression by E2F1 and EGF receptor.
Academic Article Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.
Academic Article Endostatin-cytosine deaminase fusion protein suppresses tumor growth by targeting neovascular endothelial cells.
Academic Article An attenuated Salmonella oral DNA vaccine prevents the growth of hepatocellular carcinoma and colon cancer that express alpha-fetoprotein.
Academic Article Mutant Bik expression mediated by the enhanced minimal topoisomerase IIalpha promoter selectively suppressed breast tumors in an animal model.
Academic Article Tyrosine phosphorylation controls PCNA function through protein stability.
Academic Article Mechanisms of synthetic serine protease inhibitor (FUT-175)-mediated cell death.
Academic Article Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB.
Academic Article ErbB-2 induces the cyclin D1 gene in prostate epithelial cells in vitro and in vivo.
Academic Article Novel approaches for chemosensitization of breast cancer cells: the E1A story.
Academic Article Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
Academic Article Further evidence for expression and function of the VEGF-C/VEGFR-3 axis in cancer cells.
Academic Article The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription.
Academic Article EPOX inhibits angiogenesis by degradation of Mcl-1 through ERK inactivation.
Academic Article A novel hTERT promoter-driven E1A therapeutic for ovarian cancer.
Academic Article KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta.
Academic Article Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer.
Academic Article Activation of murine double minute 2 by Akt in mammary epithelium delays mammary involution and accelerates mammary tumorigenesis.
Academic Article CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells.
Academic Article Myocyte enhancer factor-2 interacting transcriptional repressor (MITR) is a switch that promotes osteogenesis and inhibits adipogenesis of mesenchymal stem cells by inactivating peroxisome proliferator-activated receptor gamma-2.
Academic Article Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy.
Academic Article Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase.
Academic Article Hepatitis B virus X protein induces IKKa nuclear translocation via Akt-dependent phosphorylation to promote the motility of hepatocarcinoma cells.
Academic Article The roles of EZH2 in cell lineage commitment.
Academic Article Mesenchymal stem cells promote formation of colorectal tumors in mice.
Academic Article CHM-1 induces apoptosis via p38-mediated upregulation of DR5 expression in human ovarian cancer SKOV3 cells.
Academic Article FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization.
Academic Article RAC1 activation mediates Twist1-induced cancer cell migration.
Academic Article Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family.
Academic Article The effects of Photofrin-mediated photodynamic therapy on the modulation of EGFR in esophageal squamous cell carcinoma cells.
Academic Article Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776.
Academic Article Targeting the IKK?/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer.
Academic Article Colon cancer stem cells resist antiangiogenesis therapy-induced apoptosis.
Academic Article Lapatinib-mediated cyclooxygenase-2 expression via epidermal growth factor receptor/HuR interaction enhances the aggressiveness of triple-negative breast cancer cells.
Academic Article Pharmacological inactivation of Skp2 SCF ubiquitin ligase restricts cancer stem cell traits and cancer progression.
Academic Article Inhibition of type I insulin-like growth factor receptor signaling attenuates the development of breast cancer brain metastasis.
Academic Article Deubiquitylation and stabilization of PTEN by USP13.
Academic Article Epigenetic regulation of the miR142-3p/interleukin-6 circuit in glioblastoma.
Academic Article Block-Cell-Printing for live single-cell printing.
Academic Article MicroRNA-205 signaling regulates mammary stem cell fate and tumorigenesis.
Academic Article Human pro-tumor necrosis factor is a homotrimer.
Academic Article Suppression of tumorigenicity of breast cancer cells by an epithelial cell adhesion molecule (C-CAM1): the adhesion and growth suppression are mediated by different domains.
Academic Article Mapping of adenovirus 5 E1A domains responsible for suppression of neu-mediated transformation via transcriptional repression of neu.
Academic Article Reduced growth rate and transformation phenotype of the prostate cancer cells by an interferon-inducible protein, p202.
Academic Article Adenovirus-mediated N5 gene transfer inhibits tumor cell proliferation by induction of apoptosis.
Academic Article E1A is an oncogene and may immortalize normal cells, especially in combination with other oncoproteins.
Academic Article The adenoviral E1A induces p21WAF1/CIP1 expression in cancer cells.
Academic Article Prostate-specific antitumor activity by probasin promoter-directed p202 expression.
Academic Article Delivery of DNA to tumor cells using cationic liposomes.
Academic Article Enhanced paclitaxel cytotoxicity and prolonged animal survival rate by a nonviral-mediated systemic delivery of E1A gene in orthotopic xenograft human breast cancer.
Academic Article PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.
Academic Article Adenoviral E1A targets Mdm4 to stabilize tumor suppressor p53.
Academic Article Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.
Academic Article Inefficient proteasomal-degradation pathway stabilizes AP-2alpha and activates HER-2/neu gene in breast cancer.
Academic Article Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model.
Academic Article Akt-mediated phosphorylation of EZH2 suppresses methylation of lysine 27 in histone H3.
Academic Article Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis.
Academic Article Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells.
Academic Article Role of IkappaB kinase in tumorigenesis.
Academic Article Antitumor activity of an Ets protein, PEA3, in breast cancer cell lines MDA-MB-361DYT2 and BT474M1.
Academic Article A novel CRM1-dependent nuclear export signal in adenoviral E1A protein regulated by phosphorylation.
Academic Article Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization.
Academic Article Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.
Academic Article Targeted expression of BikDD eradicates pancreatic tumors in noninvasive imaging models.
Academic Article Antitumor agents. 258. Syntheses and evaluation of dietary antioxidant--taxoid conjugates as novel cytotoxic agents.
Academic Article A new mutational AKTivation in the PI3K pathway.
Academic Article Rapamycin regulates the phosphorylation of rictor.
Academic Article An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer.
Academic Article Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer.
Academic Article Peptidyl-prolyl cis/trans isomerase Pin1 is critical for the regulation of PKB/Akt stability and activation phosphorylation.
Academic Article 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition.
Academic Article Antitumor agents. 272. Structure-activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues.
Academic Article Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.
Academic Article Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies.
Academic Article Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2.
Academic Article Downregulation of microRNA miR-520h by E1A contributes to anticancer activity.
Academic Article Regulation of tumor angiogenesis by EZH2.
Academic Article Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer.
Academic Article Activation of p21(CIP1/WAF1) in mammary epithelium accelerates mammary tumorigenesis and promotes lung metastasis.
Academic Article EZH2 promotes expansion of breast tumor initiating cells through activation of RAF1-?-catenin signaling.
Academic Article EZH2 regulates neuronal differentiation of mesenchymal stem cells through PIP5K1C-dependent calcium signaling.
Academic Article CARMA3 is crucial for EGFR-Induced activation of NF-?B and tumor progression.
Academic Article Protein localization in disease and therapy.
Academic Article IKKa activation of NOTCH links tumorigenesis via FOXA2 suppression.
Academic Article Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR.
Academic Article The crosstalk of mTOR/S6K1 and Hedgehog pathways.
Academic Article Targeted expression of BikDD eliminates breast cancer with virtually no toxicity in noninvasive imaging models.
Academic Article Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling.
Academic Article Targeted expression of miR-34a using the T-VISA system suppresses breast cancer cell growth and invasion.
Academic Article Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27.
Academic Article Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking.
Academic Article Targeting the EGFR/PCNA signaling suppresses tumor growth of triple-negative breast cancer cells with cell-penetrating PCNA peptides.
Academic Article EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.
Academic Article Expression of metastasis suppressor BRMS1 in breast cancer cells results in a marked delay in cellular adhesion to matrix.
Academic Article Recombinant PML adenovirus suppresses growth and tumorigenicity of human breast cancer cells by inducing G1 cell cycle arrest and apoptosis.
Academic Article Characterization of BRCA2: temperature sensitivity of detection and cell-cycle regulated expression.
Academic Article The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells.
Academic Article HER-2/neu promotes androgen-independent survival and growth of prostate cancer cells through the Akt pathway.
Academic Article Transcriptional upregulation and activation of p55Cdc via p34(cdc2) in Taxol-induced apoptosis.
Academic Article p27 Kip1 inhibits HER2/neu-mediated cell growth and tumorigenesis.
Academic Article Localizing the EGF receptor.
Academic Article Inhibition of cancer cell growth by BRCA2.
Academic Article Enhancement of Bik antitumor effect by Bik mutants.
Academic Article Loss of aurora A/STK15/BTAK overexpression correlates with transition of in situ to invasive ductal carcinoma of the breast.
Academic Article P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells.
Academic Article Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2.
Academic Article Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway.
Academic Article Targeting ECM-integrin interaction with liposome-encapsulated small interfering RNAs inhibits the growth of human prostate cancer in a bone xenograft imaging model.
Academic Article Characterization of a novel tripartite nuclear localization sequence in the EGFR family.
Academic Article All roads lead to mTOR: integrating inflammation and tumor angiogenesis.
Academic Article Survival of cancer cells is maintained by EGFR independent of its kinase activity.
Academic Article Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.
Academic Article Galectin-3 mediates nuclear beta-catenin accumulation and Wnt signaling in human colon cancer cells by regulation of glycogen synthase kinase-3beta activity.
Academic Article p53 acetylation is crucial for its transcription-independent proapoptotic functions.
Academic Article ErbB2-mediated Src and signal transducer and activator of transcription 3 activation leads to transcriptional up-regulation of p21Cip1 and chemoresistance in breast cancer cells.
Academic Article Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors.
Academic Article ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.
Academic Article Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis.
Academic Article Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer.
Academic Article Antitumor Agents. 282. 2'-(R)-O-acetylglaucarubinone, a quassinoid from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent.
Academic Article Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells.
Academic Article Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors.
Academic Article Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.
Academic Article Cancer-targeted BikDD gene therapy elicits protective antitumor immunity against lung cancer.
Academic Article p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs.
Academic Article Deciphering the role of forkhead transcription factors in cancer therapy.
Academic Article The role of EZH2 in tumour progression.
Academic Article Epithelial-mesenchymal transition induced by TNF-a requires NF-?B-mediated transcriptional upregulation of Twist1.
Academic Article KrasG12D-induced IKK2/?/NF-?B activation by IL-1a and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.
Academic Article Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2.
Academic Article LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker.
Academic Article Beyond NF-?B activation: nuclear functions of I?B kinase a.
Academic Article TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase.
Academic Article KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling.
Academic Article EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4.
Academic Article Liposome-mediated in vivo E1A gene transfer suppressed dissemination of ovarian cancer cells that overexpress HER-2/neu.
Academic Article Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells.
Academic Article A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells.
Academic Article Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1.
Academic Article TNFalpha induces HIF-1alpha expression through activation of IKKbeta.
Academic Article Nuclear trafficking of the epidermal growth factor receptor family membrane proteins.
Academic Article The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Academic Article The Expression Patterns of ER, PR, HER2, CK5/6, EGFR, Ki-67 and AR by Immunohistochemical Analysis in Breast Cancer Cell Lines.
Academic Article Mechanisms of deregulated her2/neu expression in breast-cancer cell-lines.
Academic Article Her2 Neu overexpression counteracts the growth effects of C-myc in breast-cancer cells.
Academic Article Effects of estrogen receptor expression on growth and transformation of cells overexpressing neu.
Academic Article Growth suppression of low HER-2/neu-expressing breast cancer cell line MDA-MB-435 by tyrosine kinase inhibitor emodin.
Academic Article Suppressed autophosphorylation and tyrosine kinase-activity in revertant cell-lines expressing rat Neu oncogene.
Academic Article EZH2: a pivotal regulator in controlling cell differentiation.
Academic Article The anti-tumor activity of E1A and its implications in cancer therapy.
Academic Article IKKa restoration via EZH2 suppression induces nasopharyngeal carcinoma differentiation.
Academic Article Targeted BikDD expression kills androgen-dependent and castration-resistant prostate cancer cells.
Academic Article ADAM9 promotes lung cancer metastases to brain by a plasminogen activator-based pathway.
Academic Article MDM2-mediated degradation of SIRT6 phosphorylated by AKT1 promotes tumorigenesis and trastuzumab resistance in breast cancer.
Academic Article S6K1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer.
Academic Article E1A-mediated inhibition of HSPA5 suppresses cell migration and invasion in triple-negative breast cancer.
Academic Article De-acetylation and degradation of HSPA5 is critical for E1A metastasis suppression in breast cancer cells.
Academic Article Biochemical fractionation of membrane receptors in the nucleus.
Academic Article HER family kinase domain mutations promote tumor progression and can predict response to treatment in human breast cancer.
Academic Article Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response.
Academic Article Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells.
Academic Article The Hippo Coactivator YAP1 Mediates EGFR Overexpression and Confers Chemoresistance in Esophageal Cancer.
Academic Article Novel therapeutic strategy targeting the Hedgehog signalling and mTOR pathways in biliary tract cancer.
Academic Article Modeling familial cancer with induced pluripotent stem cells.
Academic Article Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis.
Academic Article The ZNF304-integrin axis protects against anoikis in cancer.
Academic Article Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases.
Academic Article Deep and high-resolution three-dimensional tracking of single particles using nonlinear and multiplexed illumination.
Academic Article Targeted expression of BikDD combined with metronomic doxorubicin induces synergistic antitumor effect through Bax activation in hepatocellular carcinoma.
Academic Article miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin.
Academic Article Interplay between arginine methylation and ubiquitylation regulates KLF4-mediated genome stability and carcinogenesis.
Academic Article The effect of ephrin-A1 on resistance to Photofrin-mediated photodynamic therapy in esophageal squamous cell carcinoma cells.
Academic Article Erythropoietin Stimulates Tumor Growth via EphB4.
Academic Article FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer.
Academic Article PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response.
Academic Article Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype.
Academic Article JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis.
Academic Article AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation.
Academic Article A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.
Academic Article Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity.
Academic Article A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis.
Academic Article TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1.
Academic Article The LINK-A lncRNA interacts with PtdIns(3,4,5)P3 to?hyperactivate AKT?and confer resistance to AKT?inhibitors.
Academic Article Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.
Academic Article HER2/neu overexpression counteracts the growth effects of c-myc in breast cancer cells
Academic Article Activation of keap1/nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells
Academic Article Erratum
Academic Article Erratum
Academic Article P27kip1 down-regulation is associated with trastuzumab resistance in breast cancer cells (Cancer Research (June 1, 2004) 64 (3981-3986))
Academic Article Deubiquitylation and stabilization of PTEN by USP13
Academic Article Powering Tumor Metastasis with Recycled Fuel
Academic Article Deubiquitination and Stabilization of PD-L1 by CSN5
Academic Article Erratum
Academic Article Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response
Academic Article High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma
Academic Article The VEGF-C/Flt-4 Axis Promotes Invasion and Metastasis of Cancer Cells (DOI
Academic Article Role of cancer stem cells in brain tumors
Academic Article MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells
Academic Article ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5
Academic Article The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer
Academic Article FOXC1 Activates Smoothened-Independent Hedgehog Signaling in Basal-like Breast Cancer
Academic Article Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells
Academic Article Erythropoietin Stimulates Tumor Growth via EphB4
Academic Article The expression patterns of ER, PR, HER2, CK5/6, EGFR, KI-67 and AR by immunohistochemical analysis in breast cancer cell lines
Academic Article Nuclear AURKA acquires kinase-independent transactivating function to enhance breast cancer stem cell phenotype
Academic Article EGFR signaling enhances aerobic glycolysis in triple-negative breast cancer cells to promote tumor growth and immune escape
Academic Article Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity
Academic Article Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells
Academic Article Growth inhibition of breast cancer cells by celecoxib
Academic Article S6k1 promotes invasiveness of breast cancer cells in a model of metastasis of triple-negative breast cancer
Academic Article The VEGF-C/Flt-4 Axis Promotes Invasion and Metastasis of Cancer Cells (DOI
Academic Article Suppressed autophosphorylation and tyrosine kinase activity in revertant cell lines expressing rat neu oncogene
Academic Article Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo
Academic Article Mechanisms of deregulated HER2/neu expression in breast cancer cell lines
Academic Article A novel alteration in the epidermal growth factor receptor gene is frequently detected in human non-small cell lung cancer
Academic Article A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis
Academic Article IκB Kinase Promotes Tumorigenesis through Inhibition of Forkhead FOXO3a (PII
Academic Article Structural and Functional Impacts of ER Coactivator Sequential Recruitment.
Academic Article JAK2-binding long noncoding RNA promotes breast cancer brain metastasis.
Academic Article TIE2 Associates with Caveolae and Regulates Caveolin-1 To Promote Their Nuclear Translocation.
Academic Article Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1.
Academic Article ZRANB1 Is an EZH2 Deubiquitinase and a Potential Therapeutic Target in Breast Cancer.
Academic Article Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer.
Academic Article MEASUREMENT of Protein 53 Diffusion Coefficient in Live HeLa Cells Using Raster Image Correlation Spectroscopy (RICS).
Academic Article Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer.
Academic Article The LINK-A lncRNA activates normoxic HIF1a signalling in triple-negative breast cancer.
Academic Article EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape.
Academic Article Carglumic acid promotes apoptosis and suppresses cancer cell proliferation in vitro and in vivo.
Academic Article Selective expression of constitutively active pro-apoptotic protein BikDD gene in primary mammary tumors inhibits tumor growth and reduces tumor initiating cells.
Academic Article Sciellin mediates mesenchymal-to-epithelial transition in colorectal cancer hepatic metastasis.
Academic Article Severe Hepatitis Promotes Hepatocellular Carcinoma Recurrence via NF-?B Pathway-Mediated Epithelial-Mesenchymal Transition after Resection.
Academic Article Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors.
Academic Article Analysis of Individual Signaling Complexes by mMAPS, a Flow-Proteometric System.
Academic Article Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells.
Academic Article Upregulation of lactate dehydrogenase a by 14-3-3? leads to increased glycolysis critical for breast cancer initiation and progression.
Academic Article Dicer Elicits Paclitaxel Chemosensitization and Suppresses Cancer Stemness in Breast Cancer by Repressing AXL.
Academic Article A Positive TGF-?/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer.
Academic Article Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis.
Academic Article GSK3? inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers.
Academic Article Enhancer of Zeste Homolog 2 and Histone Deacetylase 9c Regulate Age-Dependent Mesenchymal Stem Cell Differentiation into Osteoblasts and Adipocytes.
Academic Article Aurora A kinase activates YAP signaling in triple-negative breast cancer.
Academic Article Linking genomic reorganization to tumor initiation via the giant cell cycle.
Academic Article Deubiquitination and Stabilization of PD-L1 by CSN5.
Academic Article Lymphotoxin-? Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer.
Academic Article Powering Tumor Metastasis with Recycled Fuel.
Academic Article ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.
Academic Article Segmentation of 3D Trajectories Acquired by TSUNAMI Microscope: An Application to EGFR Trafficking.
Academic Article A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1a activation, tumorigenesis and?metastasis.
Academic Article JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression.
Academic Article MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Ca-based triple-negative breast cancer cells.
Academic Article Argininosuccinate synthetase 1 (ASS1) is a common metabolic marker of chemosensitivity for targeted arginine- and glutamine-starvation therapy.
Academic Article Erratum: Suspension survival mediated by PP2A-STAT3-Col XVII determines tumour initiation and metastasis in cancer stem cells.
Academic Article Metastasis regulation by PPARD expression in cancer cells.
Academic Article POMC maintains tumor-initiating properties of tumor tissue-derived long-term-cultured breast cancer stem cells.
Academic Article Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8+ T Cells and Histone Acetyltransferases.
Academic Article The role of PRMT1 in EGFR methylation and signaling in MDA-MB-468 triple-negative breast cancer cells.
Academic Article Erratum to: E1A-Mediated Inhibition of HSPA5 Suppresses Cell Migration and Invasion in Triple-Negative Breast Cancer.
Academic Article A UBE2O-AMPKa2 Axis that Promotes Tumor Initiation and Progression Offers Opportunities for Therapy.
Academic Article PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression.
Academic Article EZH2 contributes to the response to PARP inhibitors through its PARP-mediated poly-ADP ribosylation in breast cancer.
Academic Article Stress hormones promote EGFR inhibitor resistance in NSCLC: Implications for combinations with ?-blockers.
Academic Article Nanoparticle Delivery of miR-34a Eradicates Long-term-cultured Breast Cancer Stem Cells via Targeting C22ORF28 Directly.
Academic Article Actin cytoskeleton remodeling drives epithelial-mesenchymal transition for hepatoma invasion and metastasis in mice.
Academic Article The role of T-cell immunoglobulin mucin-3 and its ligand galectin-9 in antitumor immunity and cancer immunotherapy.
Academic Article HIF-1a promotes autophagic proteolysis of Dicer and enhances tumor metastasis.
Academic Article Establishment of a human embryonic stem cell line with homozygous TP53 R248W mutant by TALEN mediated gene editing.
Academic Article Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function.
Academic Article A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing.
Academic Article YY1 and HDAC9c transcriptionally regulate p38-mediated mesenchymal stem cell differentiation into osteoblasts.
Academic Article Mutant LKB1 Confers Enhanced Radiosensitization in Combination with Trametinib in KRAS-Mutant Non-Small Cell Lung Cancer.
Academic Article Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1.
Academic Article BAP1 links metabolic regulation of ferroptosis to tumour suppression.
Academic Article A flow-proteometric platform for analyzing protein concentration (FAP): Proof of concept for quantification of PD-L1 protein in cells and tissues.
Academic Article Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth.
Academic Article Expression of Long Noncoding RNA YIYA Promotes Glycolysis in Breast Cancer.
Academic Article Generation of an induced pluripotent stem cell line from an individual with a heterozygous RECQL4 mutation.
Academic Article STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.
Academic Article Inhibition of ATR downregulates PD-L1 and sensitizes tumor cells to T cell-mediated killing.
Academic Article The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells.
Academic Article Long noncoding RNA MALAT1 suppresses breast cancer metastasis.
Academic Article Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma.
Academic Article Palmitoylation stabilizes PD-L1 to promote breast tumor growth.
Academic Article PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression.
Academic Article PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.
Academic Article EGFR and c-MET Cooperate to Enhance Resistance to PARP Inhibitors in Hepatocellular Carcinoma.
Academic Article MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.
Academic Article LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.
Academic Article Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFa-induced apoptosis.
Academic Article Posttranslational Modifications of PD-L1 and Their Applications in Cancer Therapy.
Academic Article Targeting PKCd as a Therapeutic Strategy against Heterogeneous Mechanisms of EGFR Inhibitor Resistance in EGFR-Mutant Lung Cancer.
Academic Article Assessing metastatic potential of breast cancer cells based on EGFR dynamics.
Academic Article Functional roles of the human ribonuclease A superfamily in RNA metabolism and membrane receptor biology.
Academic Article Disruption of tumour-associated macrophage trafficking by the osteopontin-induced colony-stimulating factor-1 signalling sensitises hepatocellular carcinoma to anti-PD-L1 blockade.
Academic Article The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis.
Academic Article Synergism of PARP inhibitor fluzoparib (HS10160) and MET inhibitor HS10241 in breast and ovarian cancer cells.
Academic Article H2O2 induces nuclear transport of the receptor tyrosine kinase c-MET in breast cancer cells via a membrane-bound retrograde trafficking mechanism.
Concept Human Embryonic Stem Cells
Concept A549 Cells
Concept Myeloid-Derived Suppressor Cells
Concept B-Cell CLL-Lymphoma 10 Protein
Concept THP-1 Cells
Concept Pre-B-Cell Leukemia Transcription Factor 1
Concept HEK293 Cells
Concept Cell-Penetrating Peptides
Concept Pancreatic Stellate Cells
Concept Cell Cycle Checkpoints
Concept G1 Phase Cell Cycle Checkpoints
Concept S Phase Cell Cycle Checkpoints
Concept Asymmetric Cell Division
Concept Cell Engineering
Concept V-Set Domain-Containing T-Cell Activation Inhibitor 1
Concept Programmed Cell Death 1 Receptor
Concept Primary Cell Culture
Concept Human Umbilical Vein Endothelial Cells
Concept MCF-7 Cells
Concept Myeloid Cell Leukemia Sequence 1 Protein
Academic Article Activation of Aurora A kinase increases YAP stability via blockage of autophagy.
Academic Article Oncogenic lncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression.
Academic Article IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion.
Academic Article Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.
Academic Article BIK ubiquitination by the E3 ligase Cul5-ASB11 determines cell fate during cellular stress.
Academic Article A chirality-dependent action of vitamin C in suppressing Kirsten rat sarcoma mutant tumor growth by the oxidative combination: Rationale for cancer therapeutics.
Academic Article Tankyrase disrupts metabolic homeostasis and promotes tumorigenesis by inhibiting LKB1-AMPK signalling.
Academic Article Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells.
Academic Article Mechanisms Controlling PD-L1 Expression in Cancer.
Academic Article ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis.
Academic Article Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death.
Academic Article Musashi-1 promotes stress-induced tumor progression through recruitment of AGO2.
Academic Article PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo.
Academic Article ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis.
Academic Article Targeting Glycosylated PD-1 Induces Potent Antitumor Immunity.
Academic Article SLFN11 inhibits hepatocellular carcinoma tumorigenesis and metastasis by targeting RPS4X via mTOR pathway.
Academic Article The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis.
Academic Article Hepatoma cell-intrinsic TLR9 activation induces immune escape through PD-L1 upregulation in hepatocellular carcinoma.
Academic Article Author Correction: A hypoxia-responsive TRAF6-ATM-H2AX signalling axis promotes HIF1a activation, tumorigenesis and metastasis.
Academic Article Nuclear receptor tyrosine kinase transport and functions in cancer.
Academic Article Cancer Cell Metabolism Bolsters Immunotherapy Resistance by Promoting an Immunosuppressive Tumor Microenvironment.
Academic Article Pharmacologic Suppression of B7-H4 Glycosylation Restores Antitumor Immunity in Immune-Cold Breast Cancers.
Academic Article PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
Academic Article Ribonuclease 7-driven activation of ROS1 is a potential therapeutic target in hepatocellular carcinoma.
Academic Article Author Correction: PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis.
Academic Article Targeting positive feedback between BASP1 and EGFR as a therapeutic strategy for lung cancer progression.
Academic Article High RPS3A expression correlates with low tumor immune cell infiltration and unfavorable prognosis in hepatocellular carcinoma patients.
Academic Article The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin.
Academic Article Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation.
Academic Article Cigarette smoke-induced LKB1/AMPK pathway deficiency reduces EGFR TKI sensitivity in NSCLC.
Academic Article RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse.
Academic Article PRMT1 enhances oncogenic arginine methylation of NONO in colorectal cancer.
Academic Article Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy.
Academic Article Nuclear translocation of the receptor tyrosine kinase c-MET reduces the treatment efficacies of olaparib and gemcitabine in pancreatic ductal adenocarcinoma cells.
Academic Article TYRO3 induces anti-PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis.
Academic Article Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.
Academic Article Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation.
Academic Article The N-linked glycosylations of TIGIT Asn32 and Asn101 facilitate PVR/TIGIT interaction.
Academic Article Scutellaria barbata D. Don Inhibits the Main Proteases (Mpro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection.
Academic Article Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer.
Academic Article Imatinib (STI571) Inhibits the Expression of Angiotensin-Converting Enzyme 2 and Cell Entry of the SARS-CoV-2-Derived Pseudotyped Viral Particles.
Academic Article Multi-organ metastasis as destination for breast cancer cells guided by biomechanical architecture.
Academic Article AMBRA1 Promotes TGF? Signaling via Nonproteolytic Polyubiquitylation of Smad4.
Academic Article Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA.
Academic Article Functional significance of gain-of-function H19 lncRNA in skeletal muscle differentiation and anti-obesity effects.
Academic Article Molecular mechanisms and functions of pyroptosis in inflammation and antitumor immunity.
Academic Article Suppression of breast cancer cells resistant to a pure anti-estrogen with CAR-transduced natural killer cells.
Academic Article Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance.
Academic Article Mechanisms regulating PD-L1 expression in cancers and associated opportunities for novel small-molecule therapeutics.
Academic Article Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer.
Academic Article Development and characterization of anti-galectin-9 antibodies that protect T cells from galectin-9-induced cell death.
Academic Article Endothelial p130cas confers resistance to anti-angiogenesis therapy.
Academic Article PARG inhibition limits HCC progression and potentiates the efficacy of immune checkpoint therapy.
Academic Article Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies.
Academic Article Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function.
Academic Article MRNIP condensates promote DNA double-strand break sensing and end resection.
Academic Article Prospects of the potential strategies to improve the efficacy of anti-PD-1/PD-L1 therapy.
Academic Article ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer.
Academic Article PD-L1 deficiency sensitizes tumor cells to DNA-PK inhibition and enhances cGAS-STING activation.
Academic Article Endothelial p130cas confers resistance to anti-angiogenesis therapy.
Academic Article Peimine inhibits variants of SARS-CoV-2 cell entry via blocking the interaction between viral spike protein and ACE2.
Academic Article Combination treatment of arsenic trioxide and osimertinib in recurrent and metastatic head and neck squamous cell carcinoma.
Academic Article Disulfiram blocked cell entry of SARS-CoV-2 via inhibiting the interaction of spike protein and ACE2.
Academic Article GTPBP4 promotes hepatocellular carcinoma progression and metastasis via the PKM2 dependent glucose metabolism.
Academic Article DNA damage-induced paraspeckle formation enhances DNA repair and tumor radioresistance by recruiting ribosomal protein P0.
Academic Article Sphingosine kinase 1 promotes tumor immune evasion by regulating the MTA3-PD-L1 axis.
Academic Article Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion.
Academic Article Galectin-9 blockade synergizes with ATM inhibition to induce potent anti-tumor immunity.
Academic Article Disruption of SLFN11 Deficiency-Induced CCL2 Signaling and Macrophage M2 Polarization Potentiates Anti-PD-1 Therapy Efficacy in Hepatocellular Carcinoma.
Academic Article Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation.
Academic Article IRG1/Itaconate induces metabolic reprogramming to suppress ER-positive breast cancer cell growth.
Academic Article Highly Mimetic Ex Vivo Lung-Cancer Spheroid-Based Physiological Model for Clinical Precision Therapeutics.
Academic Article Detection of Gasdermin C-Mediated Cancer Cell Pyroptosis.
Academic Article RGS2-mediated translational control mediates cancer cell dormancy and tumor relapse.
Academic Article Nuclear export signal mutation of epidermal growth factor receptor enhances malignant phenotypes of cancer cells.
Academic Article Diarylheptanoid 35d overcomes EGFR TKI resistance by inducing hsp70-mediated lysosomal degradation of EGFR in EGFR-mutant lung adenocarcinoma.
Academic Article Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal.
Academic Article Endothelial p130cas confers resistance to anti-angiogenesis therapy.
Academic Article Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation.
Academic Article Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation.
Academic Article A disintegrin and metalloproteinase domain 9 facilitates SARS-CoV-2 entry into cells with low ACE2 expression.
Academic Article PD-L1 and CD58 co-regulated by CMTM6 play yin and yang to shape anti-tumor immunity.
Academic Article PD-1 blockade in combination with dasatinib potentiates induction of anti-acute lymphocytic leukemia immunity.
Academic Article Gasdermin C sensitizes tumor cells to PARP inhibitor therapy in cancer models.
Academic Article Coffee as a dietary strategy to prevent SARS-CoV-2 infection.
Academic Article Epigenetic regulation of asymmetric cell division by the LIBR-BRD4 axis.
Academic Article MRCK as a Potential Target for Claudin-Low Subtype of Breast Cancer.
Academic Article Genetic insights into carbohydrate sulfotransferase 8 and its impact on the immunotherapy efficacy of cancer.
Academic Article Inhibition of ADAM9 promotes the selective degradation of KRAS and sensitizes pancreatic cancers to chemotherapy.
Academic Article DDX3 regulates cancer immune surveillance via 3' UTR-mediated cell-surface expression of PD-L1.
Academic Article Unlocking c-MET: A comprehensive journey into targeted therapies for breast cancer.
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