G1 Phase Cell Cycle Checkpoints
"G1 Phase Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regulatory signaling systems that control the progression of the CELL CYCLE through the G1 PHASE and allow transition to S PHASE when the cells are ready to undergo DNA REPLICATION. DNA DAMAGE, or the deficiencies in specific cellular components or nutrients may cause the cells to halt before progressing through G1 phase.
| Descriptor ID |
D059585
|
| MeSH Number(s) |
G04.144.109.249 G04.144.500.320.500
|
| Concept/Terms |
G1 Phase Cell Cycle Checkpoints- G1 Phase Cell Cycle Checkpoints
- G1 Phase Checkpoints
- Checkpoint, G1 Phase
- Checkpoints, G1 Phase
- G1 Phase Checkpoint
- G1 Cell Cycle Checkpoints
G1 Phase Restriction Point- G1 Phase Restriction Point
- G1 Restriction Point
- G1 Restriction Points
- Restriction Point, G1
- Restriction Points, G1
|
Below are MeSH descriptors whose meaning is more general than "G1 Phase Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "G1 Phase Cell Cycle Checkpoints".
This graph shows the total number of publications written about "G1 Phase Cell Cycle Checkpoints" by people in this website by year, and whether "G1 Phase Cell Cycle Checkpoints" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 2 | 4 |
| 2014 | 1 | 3 | 4 |
| 2015 | 1 | 2 | 3 |
| 2016 | 2 | 3 | 5 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "G1 Phase Cell Cycle Checkpoints" by people in Profiles.
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Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Life Sci Alliance. 2023 08; 6(8).
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AGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway. BMC Cancer. 2023 Jan 02; 23(1):1.
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Cytotoxicity of Gymnopilus purpureosquamulosus extracts on hematologic malignant cells through activation of the SAPK/JNK signaling pathway. PLoS One. 2021; 16(5):e0252541.
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Dissecting the novel partners of nuclear c-Raf and its role in all-trans retinoic acid (ATRA)-induced myeloblastic leukemia cells differentiation. Exp Cell Res. 2020 09 01; 394(1):111989.
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Chemistry-First Approach for Nomination of Personalized Treatment in Lung Cancer. Cell. 2018 05 03; 173(4):864-878.e29.
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Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies. Cell Cycle. 2018; 17(4):468-478.
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Targeting Aberrant p70S6K Activation for Estrogen Receptor-Negative Breast Cancer Prevention. Cancer Prev Res (Phila). 2017 Nov; 10(11):641-650.
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Downstream targets of GWAS-detected genes for breast, lung, and prostate and colon cancer converge to G1/S transition pathway. Hum Mol Genet. 2017 04 15; 26(8):1465-1471.
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miR-564 acts as a dual inhibitor of PI3K and MAPK signaling networks and inhibits proliferation and invasion in breast cancer. Sci Rep. 2016 09 07; 6:32541.
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MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin. Cancer Res. 2016 06 15; 76(12):3604-17.