G2 Phase Cell Cycle Checkpoints
"G2 Phase Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CELL CYCLE regulatory signaling systems that are triggered by DNA DAMAGE or lack of nutrients during G2 PHASE. When triggered they restrain cells transitioning from G2 phase to M PHASE.
| Descriptor ID |
D059565
|
| MeSH Number(s) |
G04.144.109.500 G04.144.500.340.500
|
| Concept/Terms |
G2 Phase Cell Cycle Checkpoints- G2 Phase Cell Cycle Checkpoints
- G2 Phase Checkpoints
- Checkpoint, G2 Phase
- Checkpoints, G2 Phase
- G2 Phase Checkpoint
- G2 Cell Cycle Checkpoints
G2 Restriction Point- G2 Restriction Point
- G2 Restriction Points
- Restriction Point, G2
- Restriction Points, G2
Antephase Checkpoint- Antephase Checkpoint
- Antephase Checkpoints
- Checkpoint, Antephase
- Checkpoints, Antephase
|
Below are MeSH descriptors whose meaning is more general than "G2 Phase Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "G2 Phase Cell Cycle Checkpoints".
This graph shows the total number of publications written about "G2 Phase Cell Cycle Checkpoints" by people in this website by year, and whether "G2 Phase Cell Cycle Checkpoints" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "G2 Phase Cell Cycle Checkpoints" by people in Profiles.
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Synergistic Effects of Honokiol on Camptothecin-triggered Apoptosis of Drug-resistant Glioblastoma Cells via CDK1-mediated G2/M Arrest and Intrinsic ROS-Mitochondrion-dependent Pathway. Anticancer Res. 2026 Feb; 46(2):633-649.
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Biology of the Radio- and Chemo-Responsiveness in HPV Malignancies. Semin Radiat Oncol. 2021 10; 31(4):274-285.
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Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery. Nat Commun. 2018 09 28; 9(1):3982.
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Mutations of the LIM protein AJUBA mediate sensitivity of head and neck squamous cell carcinoma to treatment with cell-cycle inhibitors. Cancer Lett. 2017 04 28; 392:71-82.
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Amplification of TLK2 Induces Genomic Instability via Impairing the G2-M Checkpoint. Mol Cancer Res. 2016 10; 14(10):920-927.
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Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins. Clin Cancer Res. 2015 Nov 01; 21(21):4831-44.
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Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors a- and ?-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft. Steroids. 2013 Nov; 78(11):1071-86.
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RSK promotes G2/M transition through activating phosphorylation of Cdc25A and Cdc25B. Oncogene. 2014 May 01; 33(18):2385-94.
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PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. J Biol Chem. 2013 Feb 01; 288(5):3174-83.
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Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress. J Biol Chem. 2013 Jan 18; 288(3):1634-42.