G2 Phase Cell Cycle Checkpoints
"G2 Phase Cell Cycle Checkpoints" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CELL CYCLE regulatory signaling systems that are triggered by DNA DAMAGE or lack of nutrients during G2 PHASE. When triggered they restrain cells transitioning from G2 phase to M PHASE.
| Descriptor ID |
D059565
|
| MeSH Number(s) |
G04.144.109.500 G04.144.500.340.500
|
| Concept/Terms |
G2 Phase Cell Cycle Checkpoints- G2 Phase Cell Cycle Checkpoints
- G2 Phase Checkpoints
- Checkpoint, G2 Phase
- Checkpoints, G2 Phase
- G2 Phase Checkpoint
- G2 Cell Cycle Checkpoints
G2 Restriction Point- G2 Restriction Point
- G2 Restriction Points
- Restriction Point, G2
- Restriction Points, G2
Antephase Checkpoint- Antephase Checkpoint
- Antephase Checkpoints
- Checkpoint, Antephase
- Checkpoints, Antephase
|
Below are MeSH descriptors whose meaning is more general than "G2 Phase Cell Cycle Checkpoints".
Below are MeSH descriptors whose meaning is more specific than "G2 Phase Cell Cycle Checkpoints".
This graph shows the total number of publications written about "G2 Phase Cell Cycle Checkpoints" by people in this website by year, and whether "G2 Phase Cell Cycle Checkpoints" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "G2 Phase Cell Cycle Checkpoints" by people in Profiles.
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ATR inhibition radiosensitizes cells through augmented DNA damage and G2 cell cycle arrest abrogation. JCI Insight. 2024 Oct 08; 9(19).
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Targeting CXCR4 abrogates resistance to trastuzumab by blocking cell cycle progression and synergizes with docetaxel in breast cancer treatment. Breast Cancer Res. 2023 06 06; 25(1):62.
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Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy. Haematologica. 2023 06 01; 108(6):1500-1514.
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Biology of the Radio- and Chemo-Responsiveness in HPV Malignancies. Semin Radiat Oncol. 2021 10; 31(4):274-285.
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Wee1 Kinase Inhibitor AZD1775 Effectively Sensitizes Esophageal Cancer to Radiotherapy. Clin Cancer Res. 2020 07 15; 26(14):3740-3750.
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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy. Cancer Cell. 2019 06 10; 35(6):851-867.e7.
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Increased Chromosome Aberrations in Cells Exposed Simultaneously to Simulated Microgravity and Radiation. Int J Mol Sci. 2018 Dec 22; 20(1).
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Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models. Anticancer Drugs. 2018 10; 29(9):827-838.
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Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery. Nat Commun. 2018 09 28; 9(1):3982.
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ER? Sensitizes NSCLC to Chemotherapy by Regulating DNA Damage Response. Mol Cancer Res. 2018 02; 16(2):233-242.