"Cell Line, Transformed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eukaryotic cell line obtained in a quiescent or stationary phase which undergoes conversion to a state of unregulated growth in culture, resembling an in vitro tumor. It occurs spontaneously or through interaction with viruses, oncogenes, radiation, or drugs/chemicals.
| Descriptor ID |
D002461
|
| MeSH Number(s) |
A11.251.210.172
|
| Concept/Terms |
Cell Line, Transformed- Cell Line, Transformed
- Transformed Cell Line
- Cell Lines, Transformed
- Transformed Cell Lines
|
Below are MeSH descriptors whose meaning is more general than "Cell Line, Transformed".
Below are MeSH descriptors whose meaning is more specific than "Cell Line, Transformed".
This graph shows the total number of publications written about "Cell Line, Transformed" by people in this website by year, and whether "Cell Line, Transformed" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 2 | 4 | 6 |
| 2001 | 0 | 4 | 4 |
| 2002 | 0 | 10 | 10 |
| 2003 | 0 | 10 | 10 |
| 2004 | 0 | 3 | 3 |
| 2006 | 1 | 3 | 4 |
| 2007 | 0 | 4 | 4 |
| 2008 | 0 | 5 | 5 |
| 2009 | 0 | 5 | 5 |
| 2010 | 1 | 4 | 5 |
| 2011 | 0 | 8 | 8 |
| 2012 | 0 | 5 | 5 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 4 | 4 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 2 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cell Line, Transformed" by people in Profiles.
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Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice. J Neuroinflammation. 2019 Apr 02; 16(1):69.
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Targeting cannabinoid receptor-2 pathway by phenylacetylamide suppresses the proliferation of human myeloma cells through mitotic dysregulation and cytoskeleton disruption. Mol Carcinog. 2015 Dec; 54(12):1796-806.
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SMAD4 regulates cell motility through transcription of N-cadherin in human pancreatic ductal epithelium. PLoS One. 2014; 9(9):e107948.
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Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa. Mol Ther. 2014 Oct; 22(10):1741-52.
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Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner. Oncotarget. 2014 Mar 15; 5(5):1185-97.
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Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-?B mediates chemoresistance. Blood. 2014 Apr 24; 123(17):2691-702.
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Staurosporine is chemoprotective by inducing G1 arrest in a Chk1- and pRb-dependent manner. Carcinogenesis. 2013 Oct; 34(10):2244-52.
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Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy. Am J Physiol Renal Physiol. 2013 Apr 15; 304(8):F1127-36.
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FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res. 2013 Mar 15; 73(6):1981-92.
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Deciphering the mechanisms of tumorigenesis in human pancreatic ductal epithelial cells. Clin Cancer Res. 2013 02 01; 19(3):549-59.