"Histone Demethylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyse the removal of methyl groups from LYSINE or ARGININE residues found on HISTONES. Many histone demethylases generally function through an oxidoreductive mechanism.
| Descriptor ID |
D056466
|
| MeSH Number(s) |
D08.811.682.662.582.475
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Histone Demethylases".
Below are MeSH descriptors whose meaning is more specific than "Histone Demethylases".
This graph shows the total number of publications written about "Histone Demethylases" by people in this website by year, and whether "Histone Demethylases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
| 2015 | 3 | 1 | 4 |
| 2016 | 3 | 2 | 5 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 1 | 2 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Histone Demethylases" by people in Profiles.
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Hp1bp3 loss links chromatin reorganization to metabolic vulnerability in glioma. Proc Natl Acad Sci U S A. 2026 Jun 16; 123(24):e2601061123.
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Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 09; 609(7929):1021-1028.
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Mechanisms Regulating Muscle Protein Synthesis in CKD. J Am Soc Nephrol. 2020 11; 31(11):2573-2587.
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Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell. 2019 11 11; 36(5):528-544.e10.
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Molecular Landscape of Non-Muscle Invasive Bladder Cancer. Cancer Cell. 2017 11 13; 32(5):550-551.
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Histone Lysine Demethylase Inhibitors. Cold Spring Harb Perspect Med. 2017 Jan 03; 7(1).
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ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes. Mol Cell. 2016 08 04; 63(3):470-84.
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Genomic analyses identify molecular subtypes of pancreatic cancer. Nature. 2016 Mar 03; 531(7592):47-52.
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An essential role for UTX in resolution and activation of bivalent promoters. Nucleic Acids Res. 2016 05 05; 44(8):3659-74.
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JMJD3 as an epigenetic regulator in development and disease. Int J Biochem Cell Biol. 2015 Oct; 67:148-57.