AlkB Homolog 5, RNA Demethylase
"AlkB Homolog 5, RNA Demethylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dioxygenase and alkylation repair homolog that demethylates RNA by oxidative demethylation. It specifically demethylates N(6)-methyladenosine (m6A) RNA, the most common internal modification of MESSENGER RNA in higher eukaryotes. It can also demethylate N(6)-methyladenosine in SINGLE-STRANDED DNA.
| Descriptor ID |
D000071502
|
| MeSH Number(s) |
D08.811.074.062.937 D08.811.682.662.582.207 D08.811.682.690.416.139.968
|
| Concept/Terms |
AlkB Homolog 5, RNA Demethylase- AlkB Homolog 5, RNA Demethylase
- Alpha-Ketoglutarate-Dependent Dioxygenase AlkB Homolog 5
- Alpha Ketoglutarate Dependent Dioxygenase AlkB Homolog 5
- RNA Demethylase ALKBH5
- ALKBH5, RNA Demethylase
- Demethylase ALKBH5, RNA
- Alkylated DNA Repair Protein AlkB Homolog 5
|
Below are MeSH descriptors whose meaning is more general than "AlkB Homolog 5, RNA Demethylase".
Below are MeSH descriptors whose meaning is more specific than "AlkB Homolog 5, RNA Demethylase".
This graph shows the total number of publications written about "AlkB Homolog 5, RNA Demethylase" by people in this website by year, and whether "AlkB Homolog 5, RNA Demethylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "AlkB Homolog 5, RNA Demethylase" by people in Profiles.
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Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. Cell Stem Cell. 2020 07 02; 27(1):81-97.e8.
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m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017 04 10; 31(4):591-606.e6.