"Hyaluronan Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
| Descriptor ID |
D000076002
|
| MeSH Number(s) |
D08.811.913.400.450.480.500
|
| Concept/Terms |
Hyaluronan Synthases- Hyaluronan Synthases
- Synthases, Hyaluronan
- Hyaluronan Synthase
- Synthase, Hyaluronan
- Hyaluronic Acid Synthetase
- Synthetase, Hyaluronic Acid
- Hyaluronate Synthetase
- Synthetase, Hyaluronate
- Hyaluronan Synthetase
- Synthetase, Hyaluronan
- Hyaluronate Synthase
- Synthase, Hyaluronate
Hyaluronan Synthase 3- Hyaluronan Synthase 3
- 3, Hyaluronan Synthase
- Synthase 3, Hyaluronan
- HAS3 Protein
- Protein, HAS3
|
Below are MeSH descriptors whose meaning is more general than "Hyaluronan Synthases".
Below are MeSH descriptors whose meaning is more specific than "Hyaluronan Synthases".
This graph shows the total number of publications written about "Hyaluronan Synthases" by people in this website by year, and whether "Hyaluronan Synthases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hyaluronan Synthases" by people in Profiles.
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Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis. Br J Pharmacol. 2017 Oct; 174(19):3284-3301.
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Hyaluronan synthase 3 variant and anthracycline-related cardiomyopathy: a report from the children's oncology group. J Clin Oncol. 2014 Mar 01; 32(7):647-53.
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Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves. Pathol Res Pract. 2012 Nov 15; 208(11):642-50.
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Activation of ?-catenin signaling in androgen receptor-negative prostate cancer cells. Clin Cancer Res. 2012 Feb 01; 18(3):726-36.