"Hyaluronan Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated glucuronosyltransferases that catalyze the reaction of UDP-N-acetyl-D-glucosamine and UDP-D-glucuronate to produce HYALURONAN. HYALURONAN SYNTHASE 2 (HAS2) is essential for embryogenesis and its expression by tumor cells is associated with metastasis.
| Descriptor ID |
D000076002
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| MeSH Number(s) |
D08.811.913.400.450.480.500
|
| Concept/Terms |
Hyaluronan Synthases- Hyaluronan Synthases
- Synthases, Hyaluronan
- Hyaluronan Synthase
- Synthase, Hyaluronan
- Hyaluronic Acid Synthetase
- Synthetase, Hyaluronic Acid
- Hyaluronate Synthetase
- Synthetase, Hyaluronate
- Hyaluronan Synthetase
- Synthetase, Hyaluronan
- Hyaluronate Synthase
- Synthase, Hyaluronate
Hyaluronan Synthase 3- Hyaluronan Synthase 3
- 3, Hyaluronan Synthase
- Synthase 3, Hyaluronan
- HAS3 Protein
- Protein, HAS3
|
Below are MeSH descriptors whose meaning is more general than "Hyaluronan Synthases".
Below are MeSH descriptors whose meaning is more specific than "Hyaluronan Synthases".
This graph shows the total number of publications written about "Hyaluronan Synthases" by people in this website by year, and whether "Hyaluronan Synthases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hyaluronan Synthases" by people in Profiles.
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Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. 2021 06 14; 39(6):866-882.e11.
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Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema. Dis Model Mech. 2019 05 15; 12(5).
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Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis. Br J Pharmacol. 2017 Oct; 174(19):3284-3301.
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Hyaluronan synthase 3 variant and anthracycline-related cardiomyopathy: a report from the children's oncology group. J Clin Oncol. 2014 Mar 01; 32(7):647-53.
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Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves. Pathol Res Pract. 2012 Nov 15; 208(11):642-50.
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Activation of ?-catenin signaling in androgen receptor-negative prostate cancer cells. Clin Cancer Res. 2012 Feb 01; 18(3):726-36.
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Estrogen promotes the development of mouse cumulus cells in coordination with oocyte-derived GDF9 and BMP15. Mol Endocrinol. 2010 Dec; 24(12):2303-14.
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T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18604-9.
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Synergistic roles of BMP15 and GDF9 in the development and function of the oocyte-cumulus cell complex in mice: genetic evidence for an oocyte-granulosa cell regulatory loop. Dev Biol. 2004 Dec 01; 276(1):64-73.
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Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF. Hum Reprod. 2004 Dec; 19(12):2869-74.