"Butyrophilins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of mammalian membrane glycoproteins characterized by extracellular IMMUNOGLOBULIN DOMAINS. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The butyrophilin protein (BTN) is expressed by MAMMARY GLAND EPITHELIUM during LACTATION; whereas other members are widely expressed in other tissues, including skeletal muscle, intestine, ERYTHROID CELLS (ERMAP protein); and nerve tissue (MYELIN-OLIGODENDROCYTE GLYCOPROTEIN).
| Descriptor ID |
D000071797
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| MeSH Number(s) |
D12.776.395.550.114 D12.776.543.550.195
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Butyrophilins".
Below are MeSH descriptors whose meaning is more specific than "Butyrophilins".
This graph shows the total number of publications written about "Butyrophilins" by people in this website by year, and whether "Butyrophilins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Butyrophilins" by people in Profiles.
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BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1. J Immunother Cancer. 2024 Mar 14; 12(3).
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Ancestry and frequency of genetic variants in the general population are confounders in the characterization of germline variants linked to cancer. BMC Med Genet. 2020 05 06; 21(1):92.